Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Yuhei Hasuike"'
Autor:
Masayuki Nakamori, Daisaku Nakatani, Tomoharu Sato, Yuhei Hasuike, Seiko Kon, Toshio Saito, Harumasa Nakamura, Masanori P. Takahashi, Eisuke Hida, Hirofumi Komaki, Tsuyoshi Matsumura, Hiroto Takada, Hideki Mochizuki
Publikováno v:
EClinicalMedicine, Vol 67, Iss , Pp 102390- (2024)
Summary: Background: Myotonic dystrophy type 1 (DM1) is a devastating multisystemic disorder caused by a CTG repeat expansion in the DMPK gene, which subsequently triggers toxic RNA expression and dysregulated splicing. In a preclinical study, we dem
Externí odkaz:
https://doaj.org/article/d6af5d1bdefa4730840dadd1db1d87fc
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Myotonic dystrophy type 1 (DM1) is a dominantly inherited disorder due to a toxic gain of function of RNA transcripts containing expanded CUG repeats (CUGexp). Patients with DM1 present with multisystemic symptoms, such as muscle wasting, cognitive i
Externí odkaz:
https://doaj.org/article/db4f9712f3f549a5890957d567ed8142
Autor:
Yuhei Hasuike, Hana Tanaka, Terence Gall-Duncan, Mustafa Mehkary, Kazuhiko Nakatani, Christopher E. Pearson, Shoji Tsuji, Hideki Mochizuki, Masayuki Nakamori
Publikováno v:
Neurobiology of Disease, Vol 163, Iss , Pp 105604- (2022)
Dentatorubral–pallidoluysian atrophy (DRPLA) is a devastating genetic disease presenting myoclonus, epilepsy, ataxia, and dementia. DRPLA is caused by the expansion of a CAG repeat in the ATN1 gene. Aggregation of the polyglutamine-expanded ATN1 pr
Externí odkaz:
https://doaj.org/article/8160c9e3f4024526b8f022fa65b12ddd
Publikováno v:
International journal of molecular sciences. 23(4)
Myotonic dystrophy (DM) is a dominantly inherited multisystemic disorder affecting various organs, such as skeletal muscle, heart, the nervous system, and the eye. Myotonic dystrophy type 1 (DM1) and type 2 (DM2) are caused by expanded CTG and CCTG r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be37dc4f30a48d972f12f8f64dd6fd2e
https://pubmed.ncbi.nlm.nih.gov/35216455
https://pubmed.ncbi.nlm.nih.gov/35216455
Autor:
Masayuki Nakamori, Hiroshi Shimizu, Kotaro Ogawa, Yuhei Hasuike, Takashi Nakajima, Hidetoshi Sakurai, Toshiyuki Araki, Yukinori Okada, Akiyoshi Kakita, Hideki Mochizuki
Publikováno v:
Brain communications. 4(3)
Myotonic dystrophy type 1 is a multisystem genetic disorder involving the muscle, heart and CNS. It is caused by toxic RNA transcription from expanded CTG repeats in the 3′-untranslated region of DMPK, leading to dysregulated splicing of various ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c5c0987818c5bfb490cd4f640fced8c
https://pubmed.ncbi.nlm.nih.gov/35770133
https://pubmed.ncbi.nlm.nih.gov/35770133
Autor:
Yuhei Hasuike, Hana Tanaka, Terence Gall-Duncan, Mustafa Mehkary, Kazuhiko Nakatani, Christopher E. Pearson, Shoji Tsuji, Hideki Mochizuki, Masayuki Nakamori
Publikováno v:
Neurobiology of Disease, Vol 163, Iss, Pp 105604-(2022)
Dentatorubral–pallidoluysian atrophy (DRPLA) is a devastating genetic disease presenting myoclonus, epilepsy, ataxia, and dementia. DRPLA is caused by the expansion of a CAG repeat in the ATN1 gene. Aggregation of the polyglutamine-expanded ATN1 pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77ccc59a29e7f04a828e782ff42235d9
https://pubmed.ncbi.nlm.nih.gov/34968706
https://pubmed.ncbi.nlm.nih.gov/34968706
Autor:
Masayuki Nakamori, Hiroshi Shimizu, Kotaro Ogawa, Yuhei Hasuike, Takashi Nakajima, Hidetoshi Sakurai, Toshiyuki Araki, Yukinori Okada, Akiyoshi Kakita, Hideki Mochizuki
Publikováno v:
Brain Communications; 2022, Vol. 4 Issue 3, p1-17, 17p
Autor:
Toshio Saito, Yuhei Hasuike, Harutoshi Fujimura, Tomoko Saito, Tsuyoshi Matsumura, Saburo Sakoda
Publikováno v:
Rinsho Shinkeigaku. 58:642-645
We report cerebral embolism in 2 patients with Duchenne muscular dystrophy (DMD) after respiratory tract infection. A 31-year-old man (Case 1) was admitted to the hospital because of an upper respiratory tract infection, then suddenly developed left-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4619db35286add17be914d2d0ad4ee00
https://doi.org/10.5692/clinicalneurol.cn-001135
https://doi.org/10.5692/clinicalneurol.cn-001135
Autor:
Misa Matsui, Takuyuki Endo, Chiaki Mori, Yuhei Hasuike, Misaki Yamadera, Michiyo Koroyasu, Saburo Sakoda, Harutoshi Fujimura
Publikováno v:
Medical hypotheses. 134
Intestinal dysbiosis refers to an imbalance in the intestinal flora. The concept of small intestinal bacterial overgrowth (SIBO), a condition of abnormal proliferation of the small intestine microbiota, has been proposed as a form of small intestine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02347e5acb2df0c2d55a89c43623a3c1
https://pubmed.ncbi.nlm.nih.gov/31678900
https://pubmed.ncbi.nlm.nih.gov/31678900
Autor:
Yuhei Hasuike, Hiroyuki Wada, Masahiko Hara, Osamu Odawara, Takeharu Tsuge, Yoshitaka Kitamoto
Publikováno v:
Trans. Mat. Res. Soc. Japan. 41(No. 1):67-70
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a44d301f5aa3a5e797343fd5ab40d28
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100702408
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100702408