Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Yuhe Kan"'
Autor:
Changdong Shao, Chen Ma, Li Li, Jingyi Liu, Yanan Shen, Chen Chen, Qionglin Yang, Tianyi Xu, Zhengsong Hu, Yuhe Kan, Tingting Zhang
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 155-161 (2024)
An efficient and practical method for the synthesis of C5-brominated 8-aminoquinoline amides via a copper-promoted selective bromination of 8-aminoquinoline amides with alkyl bromides was developed. The reaction proceeds smoothly in dimethyl sulfoxid
Externí odkaz:
https://doaj.org/article/c6806e8ceaf04fa5bdcdf9f446360851
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract l-nucleosides were the most important antiviral lead compounds because they can inhibit viral DNA polymerase and DNA synthesis of many viruses, whereas they may lead to mutations in DNA replication and cause genomic instability. In this stud
Externí odkaz:
https://doaj.org/article/a46c48d18e4e4c30b4129f0092828292
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 21, Iss , Pp 604-613 (2020)
Due to highly enzymatic d-stereoselectivity, l-nucleotides (l-2′-deoxynucleoside 5′-triphosphates [l-dNTPs]) are not natural targets of polymerases. In this study, we synthesized series of l-thymidine (l-T)-modified DNA strands and evaluated the
Externí odkaz:
https://doaj.org/article/8d034e89690b4cf1b175071004224142
Autor:
Dao Lin, Yuhe Kan, Liang Yan, Yongqi Ke, Yang Zhang, Hang Luo, Xinjing Tang, Xiangjun Li, Yujian He, Li Wu
Publikováno v:
iScience, Vol 24, Iss 9, Pp 102977- (2021)
Summary: The effective utility of physiologically active molecules is crucial in numerous biological processes. However, the regulation of enzyme functions through active substances remains challenging at present. Here, glutathione (GSH), produced in
Externí odkaz:
https://doaj.org/article/3b2e170aa99248d38c3ef8527c70f449
Publikováno v:
Food Technology and Biotechnology, Vol 57, Iss 3, Pp 418-425 (2019)
Excessive intake of beer could increase serum uric acid levels, leading to high risk of gout, which was previously attributed to high purine content in beer. Recent reports that purine-rich vegetables and bean products do not cause higher uric acid l
Externí odkaz:
https://doaj.org/article/abfc1db95559470ba7558471ea8264cd
Autor:
Mengle Yang, Xinming Wang, Carlos J. Gómez‐García, Zhongxin Jin, Jianjiao Xin, Xixian Cao, Huiyuan Ma, Haijun Pang, Lichao Tan, Guixin Yang, Yuhe Kan
Publikováno v:
Advanced Functional Materials.
Autor:
Lei Hu, Aiyong He, Xinming Shen, Qinyin Gu, Jingyi Zheng, Zhen Wu, Yetao Jiang, Xiaoyu Wang, Jiaxing Xu, Yuhe Kan, Feng Xu
Publikováno v:
Green Chemistry. 24:6931-6944
A zirconium-based single-atom catalyst (Zr/NC) with Zr–N4 catalytic sites showed excellent catalytic activity, selectivity and turnover frequency for the transfer hydrogenation of HMF to BHMF in isopropanol.
Publikováno v:
Chinese Chemical Letters. 32:470-474
A rhodium-catalyzed directing group promoted selective C–H olefination reaction of indolizines at the 8-position is reported. Di-olefination at 2,8-positions also achieved with silver hexafluoroantimonate as an additive under similar reaction condi
Autor:
Yuhe Kan, Xinya Bu, Mengwu Mo, Zhenjun Yang, Dao Lin, Lu Chen, Yujian He, Liang Yan, Longfei Yuan, Li Wu
Publikováno v:
Chemical Research in Toxicology. 33:2276-2285
DNA damage can occur naturally or through environmental factors, leading to mutations in DNA replication and genomic instability in cells. Normally, natural d-nucleotides were selected by DNA polymerases. The template l-thymidine (l-T) has been shown