Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Yuh Shan Jou"'
Autor:
Yi-Wei Wang, Shu-Chuan Chen, De-Leung Gu, Yi-Chen Yeh, Jhih-Jie Tsai, Kuo-Tai Yang, Yuh-Shan Jou, Teh-Ying Chou, Tang K. Tang
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-8 (2024)
Externí odkaz:
https://doaj.org/article/0af0160c75144bc49abebe2e127ec4ae
Autor:
Hsin-Yi Chen, Shu-Jou Chan, Xinxin Liu, An-Chi Wei, Ru-In Jian, Kuan-Wei Huang, Yaw-Dong Lang, Jou-Ho Shih, Chun-Chieh Liao, Chiu-Lin Luan, Yu-Tung Kao, Shang-Yin Chiang, Pei-Wen Hsiao, Yuh-Shan Jou, Yunching Chen, Ruey-Hwa Chen
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-24 (2022)
Abstract Background Metastasis and chemoresistance are major culprits of cancer mortality, but factors contributing to these processes are incompletely understood. Methods Bioinformatics methods were used to identify the relations of Smyca expression
Externí odkaz:
https://doaj.org/article/a8ced82434e347259ea6f0bb87743738
Autor:
Yi-Wei Wang, Shu-Chuan Chen, De-Leung Gu, Yi-Chen Yeh, Jhih-Jie Tsai, Kuo-Tai Yang, Yuh-Shan Jou, Teh-Ying Chou, Tang K. Tang
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-23 (2022)
Abstract Background Metastasis is the major cause of morbidity and mortality in cancer that involves in multiple steps including epithelial–mesenchymal transition (EMT) process. Centrosome is an organelle that functions as the major microtubule org
Externí odkaz:
https://doaj.org/article/80eda9faf5454279a945279d4da5e4a8
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 1752-1763 (2022)
With the increasing incidence and mortality of human hepatocellular carcinoma (HCC) worldwide, revealing innovative targets to improve therapeutic strategies is crucial for prolonging the lives of patients. To identify innovative targets, we conducte
Externí odkaz:
https://doaj.org/article/e4d27b2ec005464a8f61097ba9184026
Autor:
Yaw-Dong Lang, Yuh-Shan Jou
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-12 (2021)
Abstract Dysregulation of nucleocytoplasmic shuttling is commonly observed in cancers and emerging as a cancer hallmark for the development of anticancer therapeutic strategies. Despite its severe adverse effects, selinexor, a selective first-in-clas
Externí odkaz:
https://doaj.org/article/d77aeb2461774c6e89adfd0fccfa2f53
Autor:
Yaw-Dong Lang, Hsin-Yi Chen, Chun-Ming Ho, Jou-Ho Shih, En-Chi Hsu, Roger Shen, Yu-Ching Lee, Jyun-Wei Chen, Cheng-Yen Wu, Hsi-Wen Yeh, Ruey-Hwa Chen, Yuh-Shan Jou
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
PSPC1 has a critical role in promoting EMT and metastasis. Here, the authors demonstrate that PSPC1 is the contextual determinant of the oncogenic switch of PTK6/β-catenin subcellular localizations to drive metastasis of hepatocellular carcinoma cel
Externí odkaz:
https://doaj.org/article/6ae4243b31584b1da82d9909f2146f87
Autor:
Yaw-Dong Lang, Yuh-Shan Jou
Publikováno v:
Molecular & Cellular Oncology, Vol 7, Iss 2 (2020)
Protein-tyrosine kinase 6 (PTK6) sequestrated by its substrate paraspeckle component 1 (PSPC1) in nucleus is a tumor suppressor. PSPC1 functions as a contextual determinant of oncogenic subcellular translocations to synergize PSPC1/β-catenin and PTK
Externí odkaz:
https://doaj.org/article/b2f7c88750014996808e57a6945f9fe0
Autor:
Zhao-Qing Shen, Yi-Fan Chen, Jim-Ray Chen, Yuh-Shan Jou, Pei-Chun Wu, Cheng-Heng Kao, Chih-Hao Wang, Yi-Long Huang, Chian-Feng Chen, Ting-Shuo Huang, Yu-Chiau Shyu, Shih-Feng Tsai, Lung-Sen Kao, Ting-Fen Tsai
Publikováno v:
Cell Reports, Vol 21, Iss 8, Pp 2198-2211 (2017)
CISD2 is located within the chromosome 4q region frequently deleted in hepatocellular carcinoma (HCC). Mice with Cisd2 heterozygous deficiency develop a phenotype similar to the clinical manifestation of nonalcoholic fatty liver disease (NAFLD) and n
Externí odkaz:
https://doaj.org/article/d9514aa1af2d4cba9ff02d52ab7e23ad
PDF file, 2015K, Table S1. MMPs and PKCs primer pairs and PCR conditions for RT-PCR. Table S2. MMPs and PKCs primer pairs and PCR conditions for ChIP assay. Table S3. Antibodies for Western blot analysis. Figure S1. The remaining subset of human canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46829206a1b1301d7738e999c48b1f75
https://doi.org/10.1158/1078-0432.22451673
https://doi.org/10.1158/1078-0432.22451673
Purpose: Histone deacetylase inhibitors (HDACi) are actively explored as new-generation epigenetic drugs but have low efficacy in cancer monotherapy. To reveal new mechanism for combination therapy, we show that HDACi induce cell death but simultaneo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d84733d1dfc4a449bce6e5b56a0428b
https://doi.org/10.1158/1078-0432.c.6522249.v1
https://doi.org/10.1158/1078-0432.c.6522249.v1