Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Yuguo Zang"'
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25282 (2011)
Crystallization conditions of an intact monoclonal IgG4 (immunoglobulin G, subclass 4) antibody were established in vapor diffusion mode by sparse matrix screening and subsequent optimization. The procedure was transferred to microbatch conditions an
Externí odkaz:
https://doaj.org/article/8b43bc8c1f10438398ad3d5cb39e9c94
Autor:
Mark D. Tully, Hans Kiefer, Yuguo Zang, Patrick Garidel, Martin Westermann, Lars V. Schäfer, Alexander Kuhn, Yannic Alber, Hendrik Göddeke, Stefan M. Kast, Michaela Blech, Sebastian Kube, Stefan Hörer
Publikováno v:
Biophys J
We report the x-ray crystal structure of intact, full-length human immunoglobulin (IgG4) at 1.8 A resolution. The data for IgG4 (S228P), an antibody targeting the natriuretic peptide receptor A, show a previously unrecognized type of Fab-Fc orientati