Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Yugo, Kanai"'
Autor:
Takaya Handa, Keita P. Mori, Akira Ishii, Shoko Ohno, Yugo Kanai, Haruko Watanabe-Takano, Akihiro Yasoda, Takashige Kuwabara, Nobuyuki Takahashi, Naoki Mochizuki, Masashi Mukoyama, Motoko Yanagita, Hideki Yokoi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Natriuretic peptides exert multiple effects by binding to natriuretic peptide receptors (NPRs). Osteocrin (OSTN) binds with high affinity to NPR-C, a clearance receptor for natriuretic peptides, and inhibits degradation of natriuretic peptid
Externí odkaz:
https://doaj.org/article/ee6ea24a24204f86924bd4ac7c5ffbb8
Autor:
Haruko Watanabe-Takano, Hiroki Ochi, Ayano Chiba, Ayaka Matsuo, Yugo Kanai, Shigetomo Fukuhara, Naoki Ito, Keisuke Sako, Takahiro Miyazaki, Kazuki Tainaka, Ichiro Harada, Shingo Sato, Yasuhiro Sawada, Naoto Minamino, Shu Takeda, Hiroki R. Ueda, Akihiro Yasoda, Naoki Mochizuki
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109380- (2021)
Summary: Mechanical stimuli including loading after birth promote bone growth. However, little is known about how mechanical force triggers biochemical signals to regulate bone growth. Here, we identified a periosteal-osteoblast-derived secretory pep
Externí odkaz:
https://doaj.org/article/f7b746b5469f41d4b717f92fbc7a86a9
Autor:
Toshihito Fujii, Keisho Hirota, Akihiro Yasoda, Akiko Takizawa, Naomi Morozumi, Ryuichi Nakamura, Takafumi Yotsumoto, Eri Kondo, Yui Yamashita, Yoriko Sakane, Yugo Kanai, Yohei Ueda, Ichiro Yamauchi, Shigeki Yamanaka, Kazumasa Nakao, Koichiro Kuwahara, Toshimasa Jindo, Mayumi Furuya, Tomoji Mashimo, Nobuya Inagaki, Tadao Serikawa, Kazuwa Nakao
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194812 (2018)
We have previously investigated the physiological role of C-type natriuretic peptide (CNP) on endochondral bone growth, mainly with mutant mouse models deficient in CNP, and reported that CNP is indispensable for physiological endochondral bone growt
Externí odkaz:
https://doaj.org/article/f529792eec9d4297a02abdca277c4211
Autor:
Keisho Hirota, Mayumi Furuya, Naomi Morozumi, Kazunori Yoshikiyo, Takafumi Yotsumoto, Toshimasa Jindo, Ryuichi Nakamura, Koichiro Murakami, Yohei Ueda, Takeshi Hanada, Hiroko Sade, Sayaka Yoshida, Kei Enomoto, Yugo Kanai, Ichiro Yamauchi, Takafumi Yamashita, Yoriko Ueda-Sakane, Toshihito Fujii, Akihiro Yasoda, Nobuya Inagaki
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0204172 (2018)
Signaling by C-type natriuretic peptide (CNP) and its receptor, natriuretic peptide receptor-B, is a pivotal stimulator of endochondral bone growth. We recently developed CNP knockout (KO) rats that exhibit impaired skeletal growth with early growth
Externí odkaz:
https://doaj.org/article/542e5c9eb917416c890d01ccb0e2e6b7
Publikováno v:
KAGAKU KOGAKU RONBUNSHU. 47:57-63
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5e0ad724b163ca6994ed314ed4aa6e2
https://doi.org/10.1252/kakoronbunshu.47.57
https://doi.org/10.1252/kakoronbunshu.47.57
Autor:
Shoko Ohno, Naoki Mochizuki, Haruko Watanabe-Takano, Yugo Kanai, Takashige Kuwabara, Motoko Yanagita, Akira Ishii, Nobuyuki Takahashi, Takaya Handa, Akihiro Yasoda, Masashi Mukoyama, Keita P. Mori, Hideki Yokoi
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Natriuretic peptides exert multiple effects by binding to natriuretic peptide receptors (NPRs). Osteocrin (OSTN) binds with high affinity to NPR-C, a clearance receptor for natriuretic peptides, and inhibits degradation of natriuretic peptides and co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a01b7d86c7a9a88dd1a5ac3ee6c2e189
https://pubmed.ncbi.nlm.nih.gov/34750411
https://pubmed.ncbi.nlm.nih.gov/34750411
Autor:
Ichiro Yamauchi, Takafumi Yamashita, Nobuya Inagaki, Yugo Kanai, Yoriko Sakane, Toshihito Fujii, Yohei Ueda, Akihiro Yasoda, Keisho Hirota
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports
Growth retardation is an important side effect of glucocorticoid (GC)-based drugs, which are widely used in various preparations to treat many pediatric diseases. We investigated the therapeutic effect of exogenous CNP-53, a stable molecular form of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99da3d8a5776f0e26d2575e79c1b1e46
http://link.springer.com/article/10.1038/s41598-019-44975-w
http://link.springer.com/article/10.1038/s41598-019-44975-w
Publikováno v:
Chemical Engineering Communications. 207:598-611
This study was performed to investigate the synthesis, kinetic and reaction mechanism of Li4SiO4 with CO2 in a slurry bubble column reactor. The Li4SiO4 powder sample was prepared via a sol...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3c42fe99df92f1a3b879de117d5587f
https://doi.org/10.1080/00986445.2019.1613229
https://doi.org/10.1080/00986445.2019.1613229
Autor:
Yoshihiko Nishiguchi, Haruko Watanabe-Takano, Shuro Umemoto, Yusuke Hata, Daisuke Fujimoto, Tomoko Kanki, Naoki Mochizuki, Akihiro Yasoda, Ryosuke Date, Yugo Kanai, Takashige Kuwabara, Yutaka Kakizoe, Masashi Mukoyama, Keita P. Mori, Takaya Handa, Yuichiro Izumi, Hideki Yokoi
Publikováno v:
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 37(3)
Background Osteocrin (OSTN), a bone-derived humoral factor, was reported to act on heart and bone by potentiating the natriuretic peptide (NP) system. Ostn gene polymorphisms have been associated with renal function decline, but its pathophysiologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4e58c2d6aecece54906835b50948f38
https://pubmed.ncbi.nlm.nih.gov/34610136
https://pubmed.ncbi.nlm.nih.gov/34610136
Autor:
Kei, Shiraishi, Yukinari, Tokoro, Yugo, Kanai, Fujio, Hayashi, Hiroyuki, Marusawa, Seiichiro, Kanaya, Takehiko, Tsumura
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 47(8)
A 67-year-old man diagnosed with clinical Stage Ⅳ gastric cancer was administered nivolumab as fourth-line chemotherapy. After 9 courses, he was emergently admitted with complaints of low blood pressure and general malaise. On the fourth hospital d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e22aed54433b93eab536576ef34ebbde
https://pubmed.ncbi.nlm.nih.gov/32829363
https://pubmed.ncbi.nlm.nih.gov/32829363