Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Yufei Xiang"'
Autor:
MengTing Wang, QingYang Chen, ShuJie Wang, Han Xie, Jun Liu, RuiXiang Huang, YuFei Xiang, YanYi Jiang, DaSheng Tian, ErBao Bian
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-33 (2023)
Abstract Super-enhancers (SEs) consist of multiple typical enhancers enriched at high density with transcription factors, histone-modifying enzymes and cofactors. Oncogenic SEs promote tumorigenesis and malignancy by altering protein-coding gene expr
Externí odkaz:
https://doaj.org/article/ee399d6e19fe42548aa5527d40f61ec8
Autor:
Xiang Yan, Xia Li, Bingwen Liu, Jiaqi Huang, Yufei Xiang, Yuhang Hu, Xiaohan Tang, Ziwei Zhang, Gan Huang, Zhiguo Xie, Houde Zhou, Zhenqi Liu, Xiangbing Wang, Richard David Leslie, Zhiguang Zhou
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-9 (2023)
Abstract Disease modifying therapies aiming to preserve β-cell function in patients with adult-onset autoimmune type 1 diabetes are lacking. Here, we conducted a multi-centre, randomized, controlled trial to assess the β-cell preservation effects o
Externí odkaz:
https://doaj.org/article/09df3a80cbe14b24aec4eed0319c5852
Autor:
Zhigang Chen, Han Xie, Jun Liu, JiaJia Zhao, Ruixiang Huang, Yufei Xiang, Haoyuan Wu, Dasheng Tian, Erbao Bian, Zhang Xiong
Publikováno v:
Cancer Biology & Therapy, Vol 25, Iss 1 (2024)
ABSTRACTGliomas are the most common type of primary brain tumor. Despite advances in treatment, it remains one of the most aggressive and deadly tumor of the central nervous system (CNS). Gliomas are characterized by high malignancy, heterogeneity, i
Externí odkaz:
https://doaj.org/article/9dcff249923b4dc6a5d54d1b89e05cb3
Autor:
Junlin Qiu, Shuoming Luo, Wenfeng Yin, Keyu Guo, Yufei Xiang, Xia Li, Zhenqi Liu, Zhiguang Zhou
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
ObjectiveFulminant type 1 diabetes may uniquely occur as a fatal adverse event during immune checkpoint inhibitor (ICI) therapy. We investigated the clinical and immunological characteristics of ICI-associated fulminant type 1 diabetes (IFD).Research
Externí odkaz:
https://doaj.org/article/78ce3372d1ca460cb5e896000acd1461
Autor:
Dapeng Sun, Zhe Sang, Yong Joon Kim, Yufei Xiang, Tomer Cohen, Anna K. Belford, Alexis Huet, James F. Conway, Ji Sun, Derek J. Taylor, Dina Schneidman-Duhovny, Cheng Zhang, Wei Huang, Yi Shi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Highly potent neutralizing nanobodies (Nbs) are of great interest as potential COVID-19 therapeutics. Here, the authors show that potent neutralizing Nbs targeting the receptor binding domain (RBD) of the SARS-CoV-2 spike protein are also effective a
Externí odkaz:
https://doaj.org/article/98aa4a733c5b42fb84aa2005c4550187
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
T lymphocytes are key players in the pathogenesis of autoimmune diabetes. We recruited subjects with T1D (n=81), LADA (n=82), T2D (n=95) and NGT (n=218) and analyzed the percentages of T-lymphocyte subsets, including T helper 1 (Th1), T helper 2 (Th2
Externí odkaz:
https://doaj.org/article/e2822317c8614dcbb5e5176d05c4ffa5
Autor:
Mary Hongying Cheng, James M. Krieger, Anupam Banerjee, Yufei Xiang, Burak Kaynak, Yi Shi, Moshe Arditi, Ivet Bahar
Publikováno v:
iScience, Vol 25, Iss 3, Pp 103939- (2022)
Summary: The emergence of SARS-CoV-2 variants necessitates rational assessment of their impact on the recognition and neutralization of the virus by the host cell. We present a comparative analysis of the interactions of Alpha, Beta, Gamma, and Delta
Externí odkaz:
https://doaj.org/article/688a6897c7d64964a3a8048ce0437b13
Autor:
Yiman Peng, Xia Li, Yufei Xiang, Xiang Yan, Houde Zhou, Xiaohan Tang, Jin Cheng, Xiaohong Niu, Jing Liu, Qiuhe Ji, Linong Ji, Gan Huang, Zhiguang Zhou
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Epitope-specific GAD65Abs and HLA-DR-DQ gene assays help improve the value of risk stratification in autoimmune diabetes mellitus and protect islet function. Identification and early intervention are important for latent autoimmune diabetes in youth
Externí odkaz:
https://doaj.org/article/bd659d62f7a74421962e685c0da76f28
Autor:
Zhuolun Shen, Yufei Xiang, Sandra Vergara, Apeng Chen, Zhengyun Xiao, Ulises Santiago, Changzhong Jin, Zhe Sang, Jiadi Luo, Kong Chen, Dina Schneidman-Duhovny, Carlos Camacho, Guillermo Calero, Baoli Hu, Yi Shi
Publikováno v:
iScience, Vol 24, Iss 9, Pp 103014- (2021)
Summary: Therapeutic and diagnostic efficacies of small biomolecules and chemical compounds are hampered by suboptimal pharmacokinetics. Here, we developed a repertoire of robust and high-affinity antihuman serum albumin nanobodies (NbHSA) that can b
Externí odkaz:
https://doaj.org/article/e246d8f7b3d242118398e3256a1ec787
Autor:
Yaqun Teng, Tribhuwan Yadav, Meihan Duan, Jun Tan, Yufei Xiang, Boya Gao, Jianquan Xu, Zhuobin Liang, Yang Liu, Satoshi Nakajima, Yi Shi, Arthur S. Levine, Lee Zou, Li Lan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Transcription-coupled homologous recombination (TC-HR) is activated by reactive oxygen species-induced DNA damage to maintain transcribed genome stability. The authors demonstrate that R loops are induced by ROS at the transcribed genome, triggering
Externí odkaz:
https://doaj.org/article/6df57d01d9cd4272a9ddbb25bd5cd4fe