Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Yuezhen Xue"'
Autor:
Joe Yeong, Bernett Lee, Jeffrey Lim, Han Chong Toh, Denise Goh, Tony Kiat Hon Lim, Yang Wu, David Mason, Mai Chan Lau, Jiang Feng Ye, Felicia Wee, Fabian Schneider, Zhen Wei Neo, Li Yen Chong, Craig Joseph, Yuezhen Xue, Parthiban Periasamy, Chan Way Ng, James Alastair Miller, Jim Mansfield, Chwee Ming Lim
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/d9e3e14b9cd84948869e7fbc31cc6ebb
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Cardiovascular diseases are the leading cause of global mortality, in which myocardial infarction accounts for 46% of total deaths. Although good progress has been achieved in medication and interventional techniques, a proven method to repair the da
Externí odkaz:
https://doaj.org/article/77d03e4cde73443c8f9cfedd4a000801
Monoclonal Antibodies against Specific p53 Hotspot Mutants as Potential Tools for Precision Medicine
Autor:
Le-Ann Hwang, Beng Hooi Phang, Oi Wah Liew, Jabed Iqbal, Xiao Hui Koh, Xin Yu Koh, Rashidah Othman, Yuezhen Xue, A. Mark Richards, David P. Lane, Kanaga Sabapathy
Publikováno v:
Cell Reports, Vol 36, Iss 6, Pp 109498- (2021)
Externí odkaz:
https://doaj.org/article/f266ff945e92477783e50248e2c7ba7a
Monoclonal Antibodies against Specific p53 Hotspot Mutants as Potential Tools for Precision Medicine
Autor:
Le-Ann Hwang, Beng Hooi Phang, Oi Wah Liew, Jabed Iqbal, Xiao Hui Koh, Xin Yu Koh, Rashidah Othman, Yuezhen Xue, A. Mark Richards, David P. Lane, Kanaga Sabapathy
Publikováno v:
Cell Reports, Vol 22, Iss 1, Pp 299-312 (2018)
Summary: The large number of mutations identified across all cancers represents an untapped reservoir of targets that can be useful for therapeutic targeting if highly selective, mutation-specific reagents are available. We report here our attempt to
Externí odkaz:
https://doaj.org/article/f1c84eea464845cc98ed94b45e71f1c7
Autor:
Floriane Meuris, Laetitia Carthagena, Agnieszka Jaracz-Ros, Françoise Gaudin, Pasquale Cutolo, Claire Deback, Yuezhen Xue, Françoise Thierry, John Doorbar, Françoise Bachelerie
Publikováno v:
PLoS Pathogens, Vol 12, Iss 12, p e1006039 (2016)
The productive human papillomavirus (HPV) life cycle is tightly linked to the differentiation and cycling of keratinocytes. Deregulation of these processes and stimulation of cell proliferation by the action of viral oncoproteins and host cell factor
Externí odkaz:
https://doaj.org/article/5912a790e7f244c88c89ffbdddbbd684
Autor:
David P. Lane, Farid J. Ghadessy, Priadarsini Maruthappan, Shifana Raja Abdeen, Teena Thakur, Pingping He, Shawn Hoon, Nick Barker, Yuezhen Xue
Upregulation of p53 target genes in response to irradiation in intestinal adenomas.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d4cc87c32af96c597cbcff2da9ebbe
https://doi.org/10.1158/0008-5472.22421565
https://doi.org/10.1158/0008-5472.22421565
Autor:
David P. Lane, Farid J. Ghadessy, Priadarsini Maruthappan, Shifana Raja Abdeen, Teena Thakur, Pingping He, Shawn Hoon, Nick Barker, Yuezhen Xue
p53 protein, activated and stabilized by posttranslational modifications, performs its major functions by inducing DNA repair, cell-cycle arrest, or apoptosis through transcriptional activation. Here, we determined the ability of p53 protein stabiliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa8407b283c175a838e32ec7aab04e7
https://doi.org/10.1158/0008-5472.c.6510963
https://doi.org/10.1158/0008-5472.c.6510963
Autor:
David P. Lane, Farid J. Ghadessy, Priadarsini Maruthappan, Shifana Raja Abdeen, Teena Thakur, Pingping He, Shawn Hoon, Nick Barker, Yuezhen Xue
Supplementary information contains "Supplementary Materials and Methods" and "Supplementary figure legends".
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b3358711e5b94c47014ae9392b7d510
https://doi.org/10.1158/0008-5472.22421559.v1
https://doi.org/10.1158/0008-5472.22421559.v1
Autor:
Yuezhen Xue, Boris San Luis, Regine J. Dress, Katzrin Binte Ahmad Murad, Florent Ginhoux, Nick Barker, David Lane
Publikováno v:
Proceedings of the National Academy of Sciences. 120
We have previously shown that proteasome inhibitor bortezomib stabilizes p53 in stem and progenitor cells within gastrointestinal tissues. Here, we characterize the effect of bortezomib treatment on primary and secondary lymphoid tissues in mice. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7db96e6c0d4fe29da34139ade9510a94
https://doi.org/10.1073/pnas.2219978120
https://doi.org/10.1073/pnas.2219978120
Autor:
Nga Luong, Wei Yan, Jeffrey Lim, Yuezhen Xue, Abu Bakr Azam, Joe Poh Sheng Yeong, Mai Chan Lau, Yiyu Cai
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::077ee92d96c17e18613bba58d71dfde0
https://doi.org/10.1136/jitc-2022-sitc2022.1288
https://doi.org/10.1136/jitc-2022-sitc2022.1288