Identification of USP2 as a novel target to induce degradation of KRAS in myeloma cells

Autor: Yingying Wang, Youping Zhang, Hao Luo, Wei Wei, Wanting Liu, Weiwei Wang, Yunzhao Wu, Cheng Peng, Yanjie Ji, Jianfang Zhang, Chujiao Zhu, Wenhui Bai, Li Xia, Hu Lei, Hanzhang Xu, Leimiao Yin, Wei Weng, Li Yang, Ligen Liu, Aiwu Zhou, Yueyue Wei, Qi Zhu, Weiliang Zhu, Yongqing Yang, Zhijian Xu, Yingli Wu

Publikováno v: Acta Pharmaceutica Sinica B, Vol 14, Iss 12, Pp 5235-5248 (2024)

Inducing the degradation of KRAS represents a novel strategy to combat cancers with KRAS mutation. In this study, we identify ubiquitin-specific protease 2 (USP2) as a novel deubiquitinating enzyme of KRAS in multiple myeloma (MM). Specifically, we d

Externí odkaz: https://doaj.org/article/d986029b2c5440409f127305b35e13e2

Efficacy of beta-blockers in the treatment of sepsis

Autor: Peng Jin, Tao Zhao, Yueyue Wei, Fang Zhao

Publikováno v: Bangladesh Journal of Pharmacology, Vol 16, Iss 1 (2021)

This meta-analysis is to systematically evaluate the efficacy and safety of beta-blockers in the treatment of sepsis. A total of 17 articles that met the inclusion criteria were included, and 10,385 cases were obtained. The meta-analysis results show

Externí odkaz: https://doaj.org/article/8b115268c9c64e77b195e00b6a1c3f3a

Decreased precipitation in the late growing season weakens an ecosystem carbon sink in a semi‐arid grassland

Autor: Rui Xiao, Dong Wang, Yaojun Zhang, Zhongling Yang, Junyong Li, Guangya Fu, Yueyue Wei, Ji Chen

Publikováno v: Yang, Z, Wei, Y, Fu, G, Xiao, R, Chen, J, Zhang, Y, Wang, D & Li, J 2021, ' Decreased precipitation in the late growing season weakens an ecosystem carbon sink in a semi-arid grassland ', Journal of Applied Ecology, vol. 58, no. 10, pp. 2101-2112 . https://doi.org/10.1111/1365-2664.13942

Net ecosystem gas exchange (NEE), a balance between gross ecosystem primary productivity (GPP) and ecosystem respiration (ER), is an important indicator of terrestrial ecosystem CO2 sink or source. Increasing frequency in droughts during different pe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f373de91040f731c138ef4881092f0cb
https://doi.org/10.1111/1365-2664.13942

From salt-filled ZIF-8 to open-door nanoporous carbon with optimized pore system for electrochemical supercapacitor with enhanced energy density

Autor: Chunfeng Xue, Wei Zhao, Qian Zhang, Jinxin Wang, Yueyue Wei, Kai Lv, Teng Wu, Yu Lin, Xiaohong Li, Xiaogang Hao

Publikováno v: Journal of Energy Storage. 51:104421

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::368bad6634ed9adba56b2c79ef02aeef
https://doi.org/10.1016/j.est.2022.104421

Encapsulating Ru(bpy)32+ in an infinite coordination polymer network: Towards a solid-state electrochemiluminescence sensing platform for histamine to evaluate fish product quality

Autor: Xuming Zhuang, Feng Luan, Xiaowen Gu, Qi Min, Xueqing Gao, Yueyue Wei, Chunyuan Tian

Publikováno v: Food Chemistry. 368:130852

In this work, we demonstrate a novel solid-state electrochemiluminescence (ECL) sensor based on the Ru(bpy)32+@terbium-guanosine monophosphate infinite coordination polymer network ((Ru(bpy)32+@Tb-GMP ICPn). Comparing with the traditional luminescenc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bc5cab44b82172c47890eb9ca7f1a57c
https://doi.org/10.1016/j.foodchem.2021.130852