Zobrazeno 1 - 10
of 411
pro vyhledávání: '"Yuetsu Tanaka"'
Autor:
Brenda Rocamonde, Sandrine Alais, Rodolphe Pelissier, Valerie Moulin, Brigitte Rimbaud, Romain Lacoste, Noemie Aurine, Camille Baquerre, Bertrand Pain, Yuetsu Tanaka, Cyrille Mathieu, Hélène Dutartre
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT The human T-cell leukemia virus (HTLV)-1 is responsible for an aggressive neurodegenerative disease (HAM/TSP) and multiple neurological alterations. The capacity of HTLV-1 to infect central nervous system (CNS) resident cells, together with
Externí odkaz:
https://doaj.org/article/12df83ae0ccc4c0480aa40a00c44249e
Publikováno v:
PLoS Pathogens, Vol 18, Iss 11, p e1010774 (2022)
Expression of the transcriptional transactivator protein Tax, encoded on the proviral plus-strand of human T-cell leukaemia virus type 1 (HTLV-1), is crucial for the replication of the virus, but Tax-expressing cells are rarely detected in fresh bloo
Externí odkaz:
https://doaj.org/article/e6cfb2e629184ebf968abc49e04f009d
Autor:
Yuetsu Tanaka, Reiko Tanaka, Naoki Imaizumi, Mariko Mizuguchi, Yoshiaki Takahashi, Masaki Hayashi, Takashi Miyagi, Junnosuke Uchihara, Kazuiku Ohshiro, Hiroaki Masuzaki, Takuya Fukushima
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Human T-cell leukemia virus type-1 (HTLV-1) establishes a long-term persistent infection in humans and causes malignant T-cell leukemia, adult T-cell leukemia (ATL). HTLV-1-specific cytotoxic T lymphocytes have been suggested to play a major role in
Externí odkaz:
https://doaj.org/article/f75639858ad049f7acad21f03e523bcc
Autor:
Sawako Nakachi, Shiki Okamoto, Keita Tamaki, Ikumi Nomura, Mamiko Tomihama, Yukiko Nishi, Takuya Fukushima, Yuetsu Tanaka, Satoko Morishima, Minako Imamura, Shiro Maeda, Masato Tsutsui, Masayuki Matsushita, Hiroaki Masuzaki
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 149, Iss , Pp 112864- (2022)
Under the dysfunction of mitochondria, cancer cells preferentially utilize both glycolytic and pentose phosphate pathways rather than electron transport chains to desperately generate adenosine triphosphate (ATP) and nicotinamide adenine dinucleotide
Externí odkaz:
https://doaj.org/article/7eec80a4bd9945bf9d218fc3aa4747d7
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010387 (2022)
The human T-cell leukemia virus type 1 (HTLV-1) transactivator protein Tax has pleiotropic functions in the host cell affecting cell-cycle regulation, DNA damage response pathways and apoptosis. These actions of Tax have been implicated in the persis
Externí odkaz:
https://doaj.org/article/a9021a4a5c1a4f949a14694d6a9f63a1
Publikováno v:
Virology Journal, Vol 16, Iss 1, Pp 1-11 (2019)
Abstract Background EOS plays an important role in maintaining the suppressive function of regulatory T cells (Tregs), and induces a regulated transformation of Tregs into T helper-like cells, which are capable of secreting proinflammatory cytokines
Externí odkaz:
https://doaj.org/article/4d155d85979e4401a5412b7f895f4a94
Autor:
Masateru Hiyoshi, Naofumi Takahashi, Youssef M Eltalkhawy, Osamu Noyori, Sameh Lotfi, Jutatip Panaampon, Seiji Okada, Yuetsu Tanaka, Takaharu Ueno, Jun-Ichi Fujisawa, Yuko Sato, Tadaki Suzuki, Hideki Hasegawa, Masahito Tokunaga, Yorifumi Satou, Jun-Ichirou Yasunaga, Masao Matsuoka, Atae Utsunomiya, Shinya Suzu
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11, p e1010126 (2021)
Human T-cell leukemia virus type 1 (HTLV-1) infects target cells primarily through cell-to-cell routes. Here, we provide evidence that cellular protein M-Sec plays a critical role in this process. When purified and briefly cultured, CD4+ T cells of H
Externí odkaz:
https://doaj.org/article/4db740f1dab34a8785d70fd6f201bafb
Autor:
Mariko Mizuguchi, Toshifumi Hara, Manami Yoshita-Takahashi, Takashi Kohda, Yuetsu Tanaka, Masataka Nakamura
Publikováno v:
Biochemistry and Biophysics Reports, Vol 26, Iss , Pp 100984- (2021)
Constitutive expression of human telomerase reverse transcriptase (hTERT) with DNA methylation of its promoter is a common phenomenon in tumor cells. We recently found that the transcriptional factor Krüppel-like factor 2 (KLF2) binds to the CpG seq
Externí odkaz:
https://doaj.org/article/5a9a2b127f4546a6adb4d22cf062c9d1
Autor:
Megumi Kato, Naoki Imaizumi, Reiko Tanaka, Mariko Mizuguchi, Masaki Hayashi, Takashi Miyagi, Junnosuke Uchihara, Kazuiku Ohshiro, Junpei Todoroki, Kennosuke Karube, Hiroaki Masuzaki, Yuetsu Tanaka, Takuya Fukushima
Publikováno v:
Viruses, Vol 14, Iss 4, p 751 (2022)
Adult T-cell leukemia/lymphoma (ATL) cells express TNF receptor type-2 (TNFR2) on their surface and shed its soluble form (sTNFR2). We previously reported that sTNFR2 levels were highly elevated in the plasma of patients with acute ATL. To investigat
Externí odkaz:
https://doaj.org/article/8b310b3561604560a1264cd370e20f17
Autor:
Kazumi Nakano, Nobuaki Karasawa, Masaaki Hashizume, Yuetsu Tanaka, Takeo Ohsugi, Kaoru Uchimaru, Toshiki Watanabe
Publikováno v:
Viruses, Vol 14, Iss 2, p 344 (2022)
The human retrovirus human T-cell leukemia virus type I (HTLV-1) infects human T cells by vertical transmission from mother to child through breast milk or horizontal transmission through blood transfusion or sexual contact. Approximately 5% of infec
Externí odkaz:
https://doaj.org/article/561ee0089d504bf8a9f5e0718bbf1f52