Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Yuesu Chen"'
Publikováno v:
Flow and Microreactor Technology in Medicinal Chemistry. :233-268
Publikováno v:
Angewandte Chemie (International ed. in English). 61(41)
Dinitrogen trioxide (N
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
N‐Demethylation of oxycodone is one of the key steps in the synthesis of important opioid antagonists like naloxone or analgesics like nalbuphine. The reaction is typically carried out using stoichiometric amounts of toxic and corrosive reagents. H
Publikováno v:
Flow Chemistry – Fundamentals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b9811928ac908b73db33738737d3ccc
https://doi.org/10.1515/9783110693676-008
https://doi.org/10.1515/9783110693676-008
Publikováno v:
European Journal of Organic Chemistry. 2019:2163-2171
The Beckmann rearrangement of oximes to amides typically requires strong acids or highly reactive, hazardous electrophiles and/or elevated temperatures to proceed. A very attractive alternative is the in situ generation of Vilsmeier-Haack reagents, b
Publikováno v:
ChemPhotoChem. 2:906-912
Publikováno v:
Organic Process Research & Development. 21:1080-1087
A continuous-flow Pd-catalyzed oxidative carbonylation protocol utilizing CO and O2 gas for the synthesis of carbonylated heterocycles is described. The optimization of temperature, pressure, CO/O2 ratio, catalyst loading, and reaction time resulted
Publikováno v:
Organic Process Research & Development. 18:1589-1592
The Schmidt reaction, the treatment with hydroazoic acid in the presence of a strong acid, converts ketones to amides directly and has been broadly applied in organic synthesis. In this communication, the Schmidt reaction of ketones was carried out i
Publikováno v:
The Journal of organic chemistry. 81(19)
A continuous flow protocol for the direct stoichiometric electrophilic amination of aromatic hydrocarbons and the Schmidt reaction of aromatic carboxylic acids using the superacidic trimethylsilyl azide/triflic acid system is described. Optimization
Publikováno v:
Organic Process Research & Development; Jul2017, Vol. 21 Issue 7, p1080-1087, 8p