Zobrazeno 1 - 10
of 325
pro vyhledávání: '"Yueqing, Gu"'
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e33382- (2024)
This work explored the changes in production decision-making trends of Chinese steel enterprises under the influence of the carbon border adjustment mechanism. First, using evolutionary game theory, the interactive mechanism of complex production str
Externí odkaz:
https://doaj.org/article/ad2cd9dfa384454aa0005536f48d0a8c
Autor:
Wen Li, Jiali Huang, Chen Shen, Weiye Jiang, Xi Yang, Jingxuan Huang, Yueqing Gu, Zhiyu Li, Yi Ma, Jinlei Bian
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 2, Pp 751-764 (2024)
Recent progress in targeted metabolic therapy of cancer has been limited by the considerable toxicity associated with such drugs. To address this challenge, we developed a smart theranostic prodrug system that combines a fluorophore and an anticancer
Externí odkaz:
https://doaj.org/article/87a2c5e865a749c483e6e2e55671671b
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract A challenge in developing proteolysis targeting chimeras (PROTACs) is the establishment of a universal platform applicable in multiple scenarios for precise degradation of proteins of interest (POIs). Inspired by the addressability, programm
Externí odkaz:
https://doaj.org/article/f00d2768bef24bffb2183f78df45f915
Publikováno v:
Energies, Vol 17, Iss 1, p 178 (2023)
Lithium-ion batteries are the backbone of novel energy vehicles and ultimately contribute to a more sustainable and environmentally friendly transportation system. Taking a 5 Ah ternary lithium-ion battery as an example, a two-dimensional axisymmetri
Externí odkaz:
https://doaj.org/article/279987d00f67442a932d65375fac8f2e
A cascade targeting strategy based on modified bacterial vesicles for enhancing cancer immunotherapy
Autor:
Yuewen Zhai, Yuying Ma, Bo Pang, Jinnan Zhang, Ying Li, Yalan Rui, Tian Xu, Yu Zhao, Zhiyu Qian, Yueqing Gu, Siwen Li
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-18 (2021)
Abstract Background As an efficient tumor immunotherapy, PD-1 antibody has been gradually used in clinical tumor treatment, but the low response rate and excessive immune response limit its extensive application. Results Herein, a therapeutic regime
Externí odkaz:
https://doaj.org/article/03f5692e133c49b2831979716aff5f5b
Autor:
Rohit Bavi, Zhang Hang, Parikshit Banerjee, Md Aquib, Mahendra Jadhao, Niraj Rane, Sneha Bavi, Raghunath Bhosale, Kisan Kodam, Byong-Hun Jeon, Yueqing Gu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 21, Iss , Pp 1074-1086 (2020)
Aptamers are small, functional single-stranded DNA or RNA oligonucleotides that bind to their targets with high affinity and specificity. Experimentally, aptamers are selected by the systematic evolution of ligands by exponential enrichment (SELEX) m
Externí odkaz:
https://doaj.org/article/9ebe9ebd48054c4992e6c0533ee78a12
Publikováno v:
Nanomaterials, Vol 12, Iss 18, p 3150 (2022)
The in situ lactate oxidase (LOx) catalysis is highly efficient in reducing oxygen to H2O2 due to the abundant lactate substrate in the hypoxia tumor microenvironment. Dynamic therapy, including chemodynamic therapy (CDT), photodynamic therapy (PDT),
Externí odkaz:
https://doaj.org/article/2e759c9650b24055aa746e0acfc5c4b5
Publikováno v:
Nano-Micro Letters, Vol 11, Iss 1, Pp 1-18 (2019)
Abstract Recently emerged cancer immunochemotherapy has provided enormous new possibilities to replace traditional chemotherapy in fighting tumor. However, the treatment efficacy is hampered by tumor hypoxia-induced immunosuppression in tumor microen
Externí odkaz:
https://doaj.org/article/a13c4cab9537478ba3b737f29d86187f
Publikováno v:
Advanced Science, Vol 8, Iss 8, Pp n/a-n/a (2021)
Abstract Atherosclerotic plaque is the primary cause of cardiovascular disorders and remains a therapeutic hurdle for the early intervention of atherosclerosis. Traditional clinical strategies are often limited by surgery‐related complications or u
Externí odkaz:
https://doaj.org/article/6109bc48f6bb41ae9e4e94be99846bc9
Publikováno v:
ACS Applied Materials & Interfaces. 14:36957-36965
Effective targeting of nanomedicine is still an intricacy since unsatisfactory clinical trial feedback demonstrated their inadequate concentration at the desired area. However, the regulatory effect of ligand-modification patterns on the targeting ef