Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Yuen-Ling Chan"'
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
RAD51 has been implicated in replication fork processing and restart in response to replication stress. Here, authors reveal mechanistic aspects of non-enzymatic roles of RAD51 for fork reversal and cooperation with FBH1.
Externí odkaz:
https://doaj.org/article/52fab4c5a1a94e78b06410197589ffc4
Publikováno v:
Current opinion in genetics & development
Members of the RecA family of strand exchange proteins carry out the central reaction in homologous recombination. These proteins are DNA-dependent ATPases, although their ATPase activity is not required for the key functions of homology search and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95daafef5bbd5c8cc6c78d597abbbe4a
https://doi.org/10.1016/j.gde.2021.06.016
https://doi.org/10.1016/j.gde.2021.06.016
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications
Nature Communications
The central recombination enzyme RAD51 has been implicated in replication fork processing and restart in response to replication stress. Here, we use a separation-of-function allele of RAD51 that retains DNA binding, but not D-loop activity, to revea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1790a224c6367fed841d9e2be58468c3
http://link.springer.com/article/10.1038/s41467-019-12297-0
http://link.springer.com/article/10.1038/s41467-019-12297-0
Publikováno v:
Nucleic Acids Research
Dmc1 catalyzes homology search and strand exchange during meiotic recombination in budding yeast and many other organisms including humans. Here we reconstitute Dmc1 recombination in vitro using six purified proteins from budding yeast including Dmc1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b632d66178976b1ca31ad83e209e02de
https://doi.org/10.1093/nar/gky1160
https://doi.org/10.1093/nar/gky1160
Dmc1 catalyzes homology search and strand exchange during meiotic recombination in budding yeast and many other organisms including humans. Here we reconstitute Dmc1 recombinationin vitrousing six purified proteins including Dmc1 and its accessory pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40322efa314bfca4cc7b8c645d9e1c75
https://doi.org/10.1101/356592
https://doi.org/10.1101/356592
Autor:
Yuen-Ling Chan, Douglas K. Bishop
Budding yeast Dmc1 is a member of the RecA family of strand exchange proteins essential for homologous recombination (HR) during meiosis. Dmc1 mediates the steps of homology search and DNA strand exchange reactions that are central to HR. To achieve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4a1c8f7a11b22dbb22d14132e0b99ce
https://doi.org/10.1016/bs.mie.2017.12.003
https://doi.org/10.1016/bs.mie.2017.12.003
Publikováno v:
Nucleic Acids Research
Efficient repair of chromosomal double-strand breaks (DSBs) by homologous recombination relies on the formation of a Rad51 recombinase filament that forms on single-stranded DNA (ssDNA) created at DSB ends. This filament facilitates the search for a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b8a7b889ce5cc076ee9a0e3854263ee
https://doi.org/10.1093/nar/gkv525
https://doi.org/10.1093/nar/gkv525
Publikováno v:
Science. 337:1222-1225
Relegated to Accessory Critical aspects of meiosis, the specialized cell division that makes haploid gametes and spores, evolved from those of the normal mitotic cell cycle. In mitosis, the RecA homolog Rad51 is required for the homology-mediated rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec816f14046074b7091998a4e1a8176f
https://doi.org/10.1126/science.1219379
https://doi.org/10.1126/science.1219379
Autor:
Mara Prentiss, Yuen-Ling Chan, Claudia Danilowicz, Vincent William Coljee, Julea Vlassakis, Douglas K. Bishop, Alyson Conover, Efraim Feinstein
Publikováno v:
Nucleic Acids Research
A RecA–single-stranded DNA (RecA–ssDNA) filament searches a genome for sequence homology by rapidly binding and unbinding double-stranded DNA (dsDNA) until homology is found. We demonstrate that pulling on the opposite termini (3′ and 5′) of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57e4267bd1a30436d1f7fdc23efa9a63
https://doi.org/10.1093/nar/gkr855
https://doi.org/10.1093/nar/gkr855
Autor:
Yuen-Ling Chan, Ira G. Wool
Publikováno v:
Journal of Molecular Biology. 378:12-19
The elongation stage of protein synthesis consists of repeated cycles of the binding of aminoacyl-tRNA, peptide bond formation, and translocation. The process is normally catalyzed by the elongation factors Tu and G; however, the reactions can procee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deca2c33b8e10dd7b261fc4e76382c97
https://doi.org/10.1016/j.jmb.2008.02.016
https://doi.org/10.1016/j.jmb.2008.02.016