Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Yuen San Chan"'
Autor:
Chandra Sekhar Amara, Karthik Reddy Kami Reddy, Yang Yuntao, Yuen San Chan, Danthasinghe Waduge Badrajee Piyarathna, Lacey Elizabeth Dobrolecki, David J. H. Shih, Zhongcheng Shi, Jun Xu, Shixia Huang, Matthew J. Ellis, Andrea B. Apolo, Leomar Y. Ballester, Jianjun Gao, Donna E. Hansel, Yair Lotan, H. Courtney Hodges, Seth P. Lerner, Chad J. Creighton, Arun Sreekumar, W. Jim Zheng, Pavlos Msaouel, Shyam M. Kavuri, Nagireddy Putluri
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract SMARCB1 loss has long been observed in many solid tumors. However, there is a need to elucidate targetable pathways driving growth and metastasis in SMARCB1-deficient tumors. Here, we demonstrate that SMARCB1 deficiency, defined as genomic S
Externí odkaz:
https://doaj.org/article/92dacc4a9b18472087b40b7343faadf4
Autor:
Heng Zou, Zihan Yang, Yuen-San Chan, Sung-king Au Yeung, Md Kowsar Alam, Tongxu Si, Tao Xu, Mengsu Yang
Publikováno v:
iScience, Vol 25, Iss 3, Pp 103917- (2022)
Summary: Collective cell migration is associated with cancer metastasis. Cancer fingers are formed when groups of migrating cancer cells follow the leader cells in the front. Epithelial to mesenchymal transition (EMT) is a critical process of cancer
Externí odkaz:
https://doaj.org/article/aabc7bb22626463d91a7d58dc85c1dd3
Autor:
Courtney Chambers, Katerina Cermakova, Yuen San Chan, Kristen Kurtz, Katharina Wohlan, Andrew Henry Lewis, Christiana Wang, Anh Pham, Milan Dejmek, Michal Sala, Mario Loeza Cabrera, Rogelio Aguilar, Radim Nencka, H. Daniel Lacorazza, Rachel E. Rau, H. Courtney Hodges
Publikováno v:
Cancer Research. 83:983-996
In acute myeloid leukemia (AML), SWI/SNF chromatin remodeling complexes sustain leukemic identity by driving high levels of MYC. Previous studies have implicated the hematopoietic transcription factor PU.1 (SPI1) as an important target of SWI/SNF inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a0171a9011c1cfa79f3fcc276c41322
https://doi.org/10.1158/0008-5472.can-22-2129
https://doi.org/10.1158/0008-5472.can-22-2129
Autor:
Waqas Muhammad Usman, Tin Chanh Pham, Yuk Yan Kwok, Luyen Tien Vu, Victor Ma, Boya Peng, Yuen San Chan, Likun Wei, Siew Mei Chin, Ajijur Azad, Alex Bai-Liang He, Anskar Y. H. Leung, Mengsu Yang, Ng Shyh-Chang, William C. Cho, Jiahai Shi, Minh T. N. Le
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
RNA delivery for disease treatment often has low uptake efficiencies and cytotoxicity. Here the authors produce extracellular vesicles from red blood cells for in vivo cargo delivery.
Externí odkaz:
https://doaj.org/article/350bd6e6bc6e47cb83dee5c809576fb8
Autor:
H. Courtney Hodges, Rachel E. Rau, H. Daniel Lacorazza, Radim Nencka, Rogelio Aguilar, Mario Loeza Cabrera, Michal Sala, Milan Dejmek, Anh Pham, Christiana Wang, Andrew Henry Lewis, Katharina Wohlan, Kristen Kurtz, Yuen San Chan, Katerina Cermakova, Courtney Chambers
Supplementary Materials
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42cb047ddab86b1b962b42e21c8ce8a8
https://doi.org/10.1158/0008-5472.22549670.v1
https://doi.org/10.1158/0008-5472.22549670.v1
Autor:
Stephen C. Mack, Benjamin Deneen, Kelsey C. Bertrand, Claudia L. Kleinman, Nada Jabado, Joanna Yi, Richard J. Gilbertson, Sameer Agnihotri, Kristian W. Pajtler, Donald W. Parsons, Susan M. Blaney, Murali M. Chintagumpala, Thomas F. Westbrook, Irtisha Singh, H. Courtney Hodges, Charles Y. Lin, Stefan M. Pfister, Daisuke Kawauchi, Felix Sahm, Luz A. De León, Peter R. Wang, Madeline Ngo, Sarah G. Injac, Baoli Hu, Robert Kupp, Kathleen Kong, Kristen L. Karlin, Calla Olson, Yuen San Chan, Ann-Catherine J. Stanton, Brian J. Golbourn, Dana Tlais, Alisha Kardian, Minerva Solis, Austin J. Stuckert, Bryan Rivas, Selin Jessa, Hsiao-Chi Chen, Srinidhi Varadharajan, Yanhua Zhao, Amir Arabzade
93 gene signature that characterizes ZFTA-Rela mouse and human tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2455a45bb7a7160f6ff2e0c7dedb37da
https://doi.org/10.1158/2159-8290.22539655.v1
https://doi.org/10.1158/2159-8290.22539655.v1
Autor:
Stephen C. Mack, Benjamin Deneen, Kelsey C. Bertrand, Claudia L. Kleinman, Nada Jabado, Joanna Yi, Richard J. Gilbertson, Sameer Agnihotri, Kristian W. Pajtler, Donald W. Parsons, Susan M. Blaney, Murali M. Chintagumpala, Thomas F. Westbrook, Irtisha Singh, H. Courtney Hodges, Charles Y. Lin, Stefan M. Pfister, Daisuke Kawauchi, Felix Sahm, Luz A. De León, Peter R. Wang, Madeline Ngo, Sarah G. Injac, Baoli Hu, Robert Kupp, Kathleen Kong, Kristen L. Karlin, Calla Olson, Yuen San Chan, Ann-Catherine J. Stanton, Brian J. Golbourn, Dana Tlais, Alisha Kardian, Minerva Solis, Austin J. Stuckert, Bryan Rivas, Selin Jessa, Hsiao-Chi Chen, Srinidhi Varadharajan, Yanhua Zhao, Amir Arabzade
Figure S2 supporting expression and localization of ZRfus in the mouse IUE model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5100705dc6a0f49c6241a385bfa4fe37
https://doi.org/10.1158/2159-8290.22539676
https://doi.org/10.1158/2159-8290.22539676
Autor:
Stephen C. Mack, Benjamin Deneen, Kelsey C. Bertrand, Claudia L. Kleinman, Nada Jabado, Joanna Yi, Richard J. Gilbertson, Sameer Agnihotri, Kristian W. Pajtler, Donald W. Parsons, Susan M. Blaney, Murali M. Chintagumpala, Thomas F. Westbrook, Irtisha Singh, H. Courtney Hodges, Charles Y. Lin, Stefan M. Pfister, Daisuke Kawauchi, Felix Sahm, Luz A. De León, Peter R. Wang, Madeline Ngo, Sarah G. Injac, Baoli Hu, Robert Kupp, Kathleen Kong, Kristen L. Karlin, Calla Olson, Yuen San Chan, Ann-Catherine J. Stanton, Brian J. Golbourn, Dana Tlais, Alisha Kardian, Minerva Solis, Austin J. Stuckert, Bryan Rivas, Selin Jessa, Hsiao-Chi Chen, Srinidhi Varadharajan, Yanhua Zhao, Amir Arabzade
More than 60% of supratentorial ependymomas harbor a ZFTA–RELA (ZRfus) gene fusion (formerly C11orf95–RELA). To study the biology of ZRfus, we developed an autochthonous mouse tumor model using in utero electroporation (IUE) of the embryonic mous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e3a974b88b13a244bee5e4ff38026e0
https://doi.org/10.1158/2159-8290.c.6549148.v1
https://doi.org/10.1158/2159-8290.c.6549148.v1
Autor:
H. Courtney Hodges, Rachel E. Rau, H. Daniel Lacorazza, Radim Nencka, Rogelio Aguilar, Mario Loeza Cabrera, Michal Sala, Milan Dejmek, Anh Pham, Christiana Wang, Andrew Henry Lewis, Katharina Wohlan, Kristen Kurtz, Yuen San Chan, Katerina Cermakova, Courtney Chambers
Motif profiling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::034e88327dc89c967389d1e7b7dd2f37
https://doi.org/10.1158/0008-5472.22361380.v1
https://doi.org/10.1158/0008-5472.22361380.v1
Autor:
H. Courtney Hodges, Rachel E. Rau, H. Daniel Lacorazza, Radim Nencka, Rogelio Aguilar, Mario Loeza Cabrera, Michal Sala, Milan Dejmek, Anh Pham, Christiana Wang, Andrew Henry Lewis, Katharina Wohlan, Kristen Kurtz, Yuen San Chan, Katerina Cermakova, Courtney Chambers
Gene set enrichment analyses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7bfa8b231c9c1ef5daa8c40c6bc32d
https://doi.org/10.1158/0008-5472.22361383.v1
https://doi.org/10.1158/0008-5472.22361383.v1