Výsledky vyhledávání - "Yuen Kuen Cheong"

Rapid purification of recombinant dengue and West Nile virus envelope Domain III proteins by metal affinity membrane chromatography

Autor: Shu Min Pua, Anthony Jin Shun Chua, Yuen Kuen Cheong, Mah Lee Ng, Lik Chern Melvin Tan, Li Shan Liza Goh

Publikováno v: Protein Expression and Purification. 74:129-137

Arthropod-borne flaviviruses such as dengue virus (DENV) and West Nile virus (WNV) pose significant health threats to the global community. Due to escalating numbers of DENV and WNV infections worldwide, development of an effective vaccine remains a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04b1441cb6fa2270d0a81fbaa7a0fa0f
https://doi.org/10.1016/j.pep.2010.06.015

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Peptidomimetic ethyl propenoate covalent inhibitors of the enterovirus 71 3C protease: a P2–P4 study

Autor: Anders Poulsen, Yong Wah Tan, Zi Xian Ngoh, Justin Jang Hann Chu, Qiu Ying Lau, Jianhe Peng, Melgious Jin Yan Ang, Yuen Kuen Cheong, C. S. Brian Chia, Fui Mee Ng, Jeffrey Hill, Siew Wen Then, Thomas H. Keller

Enterovirus 71 (EV71) is a highly infectious pathogen primarily responsible for Hand, Foot, and Mouth Disease, particularly among children. Currently, no approved antiviral drug has been developed against this disease. The EV71 3C protease is deemed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1534d9b04c54c2683da080411cd0122

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Identification of cell surface markers glypican-4 and CD200 that differentiate human corneal endothelium from stromal fibroblasts

Autor: Heng-Pei Ang, Xin-Yi Seah, Zi Xian Ngoh, Zhenzhi Chng, Alan Colman, Jodhbir S. Mehta, Yuen Kuen Cheong, William Sun, Gary S L Peh

Publikováno v: Investigative ophthalmologyvisual science. 54(7)

Purpose There is a lack of definitive cell surface markers to differentiate cultured human corneal endothelial cells (HCECs) from stromal fibroblasts, which could contaminate HCEC cultures. The aim of our study is to discover cell surface antigens on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a8978313ea19d9d3535d5ad91b9839
https://pubmed.ncbi.nlm.nih.gov/23744997

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Dephosphorylation of West Nile virus capsid protein enhances the processes of nucleocapsid assembly

Autor: Mah Lee Ng, Yuen Kuen Cheong

Publikováno v: Microbes and infection. 13(1)

West Nile virus (WNV) capsid (C) protein is one of the three viral structural proteins and it encapsidates the viral RNA to form the nucleocapsid. It is known to be a multifunctional protein involved in assembly and apoptosis. WNV C protein was previ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8e973685a2d855959e4a3b1d7b065b8
https://pubmed.ncbi.nlm.nih.gov/21034847

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West Nile virus capsid protein interaction with importin and HDM2 protein is regulated by protein kinase C-mediated phosphorylation

Autor: Yuen Kuen Cheong, Mah Lee Ng, Raghavan Bhuvanakantham

Publikováno v: Microbes and infection. 12(8-9)

West Nile virus (WNV) capsid (C) protein was shown to enter the nucleus via importin-mediated pathway and induce apoptosis although the precise regulatory mechanisms for such events have remained elusive. In this study, it was shown that WNV C protei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3f408472d77dff2bfac832bdf0fbcc2
https://pubmed.ncbi.nlm.nih.gov/20417716

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