Antiviral Activity, Safety, and Pharmacokinetics of Capsid Assembly Modulator NVR 3-778 in Patients with Chronic HBV Infection.

Autor: Yuen MF; Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong. Electronic address: mfyuen@hkucc.hku.hk., Gane EJ; University of Auckland, Auckland, New Zealand., Kim DJ; Department of Internal Medicine, Hallym University, Chuncheon Sacred Heart Hospital, Gangwon-do, Republic of Korea., Weilert F; Waikato Hospital, Hamilton, New Zealand., Yuen Chan HL; Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong., Lalezari J; Quest Clinical Research, San Francisco, California., Hwang SG; Department of Internal Medicine, CHA Bundang Medical Center, Gyeonggi-do, Republic of Korea., Nguyen T; Research and Education, Inc., San Diego, California., Flores O; Novira Therapeutics, Doylestown, Pennsylvania., Hartman G; Chemistry, Novira Therapeutics, Doylestown, Pennsylvania., Liaw S; Clinical Operations, Novira Therapeutics, Doylestown, Pennsylvania., Lenz O; Janssen Pharmaceutica NV, Beerse, Belgium., Kakuda TN; Clinical Pharmacology, Janssen Biopharma, South San Francisco, California., Talloen W; Janssen Pharmaceutica NV, Beerse, Belgium., Schwabe C; Auckland Clinical Studies, Auckland, New Zealand., Klumpp K; Discovery Research, Novira Therapeutics, Doylestown, Pennsylvania., Brown N; Novira Therapeutics, Doylestown, Pennsylvania.

Publikováno v: Gastroenterology [Gastroenterology] 2019 Apr; Vol. 156 (5), pp. 1392-1403.e7. Date of Electronic Publication: 2019 Jan 06.