Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Yuelong, Jiang"'
Publikováno v:
IEEE Access, Vol 12, Pp 127825-127835 (2024)
The efficient and accurate detection of foreign objects invading railway tracks is of paramount importance in safeguarding the safety of train operations. Addressing the issue of the problem of the low efficiency of the existing foreign objects detec
Externí odkaz:
https://doaj.org/article/d3c73257e91e4844998a871531945fc6
Autor:
Jinshui Tan, Mengya Zhong, Yanyan Hu, Guangchao Pan, Jingwei Yao, Yuanfang Tang, Hongpeng Duan, Yuelong Jiang, Weihang Shan, Jiaqi Lin, Yating Liu, Jiewen Huang, Huijian Zheng, Yong Zhou, Guo Fu, Zhifeng Li, Bing Xu, Jie Zha
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Refractory or relapsed (R/R) AML is the most challenging form of AML to treat. Due to frequent genetic mutations, therapy alternatives are limited. Here, we identified the role of ritanserin and its target DGKα in AML. Several AML cell line
Externí odkaz:
https://doaj.org/article/ed795b3fcb3644ed9cb15069fa02179c
Autor:
Haijun Zhao, Yuelong Jiang, Fusheng Lin, Mengya Zhong, Jinshui Tan, Yong Zhou, Long Liu, Guowei Li, Manman Deng, Bing Xu
Publikováno v:
Experimental Hematology & Oncology, Vol 11, Iss 1, Pp 1-14 (2022)
Abstract Background Leukemia stem cells (LSCs) are responsible for the initiation and perpetuation of acute myeloid leukemia (AML), and also represent leukemia relapse reservoirs with limited therapeutic approaches. Thus, additional treatment strateg
Externí odkaz:
https://doaj.org/article/8041ed2f41ae4be8952ae24cc4b778f9
Autor:
Qinwei Chen, Suqi Deng, Manman Deng, Yuanfei Shi, Mengya Zhong, Lihong Ding, Yuelong Jiang, Yong Zhou, Bing Z. Carter, Bing Xu
Publikováno v:
Experimental Hematology & Oncology, Vol 11, Iss 1, Pp 1-4 (2022)
Abstract Dysregulation of MDM2, a p53 negative regulator, frequently occurs in acute myeloid leukemia (AML) and is associated with unfavorable prognoses, rendering the p53-MDM2 axis an attractive target for the development of small-molecule inhibitor
Externí odkaz:
https://doaj.org/article/c1fbba5b8da04b61859915b7ecb0f9dd
Autor:
Liying Feng, Kai Chen, Wei Huang, Yuelong Jiang, Xihuan Sun, Yong Zhou, Li Li, Yin Li, Xianming Deng, Bing Xu
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract Double-hit lymphoma is one of the most aggressive and refractory lymphoma subtypes with recurrent genetic abnormalities of MYC and BCL-2 or BCL6 rearrangement, leading to a poor prognosis in the present clinical practice. Therefore, new ther
Externí odkaz:
https://doaj.org/article/a0f3b42867ad412899b65520216ba13e
Autor:
Qiuling Chen, Qian Lai, Yuelong Jiang, jingwei Yao, Qinwei Chen, Li Zhang, Caiyan Wang, Yong Zhou, Manman Deng, Bing Xu
Publikováno v:
Translational Oncology, Vol 25, Iss , Pp 101516- (2022)
Objectives: Despite advances in the development of novel targeted therapies, the need for B-ALL alternative treatments has not been met. Anlotinib could blunt the proangiogenic activity of VEGFR, PDGFR, and FGFR, and has shown strong antitumor activi
Externí odkaz:
https://doaj.org/article/7fd226d4a20c4acfbd8b21ecb37cb592
Autor:
Mengya Zhong, Jinshui Tan, Guangchao Pan, Yuelong Jiang, Hui Zhou, Qian Lai, Qinwei Chen, Liyuan Fan, Manman Deng, Bing Xu, Jie Zha
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The key factors leading to transformed follicular lymphoma (t-FL) include the aberrations of epigenetic modifiers as early and driving events, especially mutations in the gene encoding for histone acetyltransferase. Therefore, reversal of this phenom
Externí odkaz:
https://doaj.org/article/3d713885de444a33b83a276132d8180e
Autor:
Yuanfang Tang, Mengya Zhong, Guangchao Pan, Jinshui Tan, Chendi Xie, Yuelong Jiang, Jingwei Yao, Weihang Shan, Jiaqi Lin, Jiewen Huang, Yating Liu, Zhifeng Li, Bing Xu, Jie Zha
Publikováno v:
Pharmaceuticals, Vol 16, Iss 1, p 15 (2022)
Transformed follicular lymphoma (t-FL), for which there is no efficient treatment strategy, has a rapid progression, treatment resistance, and poor prognosis, which are the main reasons for FL treatment failure. In this study, we identified a promisi
Externí odkaz:
https://doaj.org/article/40f2f2cd18014b5ab8bc4a9c0019fd00
Autor:
Yuelong Jiang, Long Liu, Yirong Jiang, Zhifeng Li, Liying Feng, Xinguo Zhuang, Zhijuan Lin, Qiuling Chen, Guoshu Chen, Jixiang He, Guowei Li, Jie Zha, Bing Xu
Publikováno v:
Pharmaceuticals, Vol 15, Iss 11, p 1313 (2022)
Leukemia stem cells (LSCs) constitute the critical barrier to the cure of acute myeloid leukemia (AML) due to their chemoresistance and immune evasion property. Herein, the role of anlotinib, a multiple tyrosine kinase inhibitor, in killing LSCs and
Externí odkaz:
https://doaj.org/article/ca3c04b03c5d4771b3f7cbb44977b3b2
Autor:
Yuelong JIANG1 027Lanto@gmail.com, TAŞKIN, Nazım2 nazimtaskin@gmail.com
Publikováno v:
Ege Academic Review. Jan2023, Vol. 23 Issue 1, p27-42. 15p.