Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Yuekui Li"'
Publikováno v:
Journal of Neurochemistry. 92:546-553
Both the astrocytic cytokine S100B and the pro-inflammatory interleukin-1 (IL-1) are elevated in Alzheimer's disease, and each has been implicated in Alzheimer-related neuropathology. We examined the gene-regulatory events through which S100B induces
Autor:
Steven W. Barger, Dong-ge Liu, S. Woodward, Robert E. Mrak, Ling Liu, Yuekui Li, W. Sue T. Griffin
Publikováno v:
Journal of Neuroimmunology. 147:50-55
The fate of the fragmented DNA (fDNA) observed in neuronal nuclei in Alzheimer brain is unknown. However, its fate is suggested as fDNA is found in the cytoplasm of adjacent activated microglia. After a brief incubation with fDNA, approximately 70% o
Publikováno v:
The Journal of Neuroscience. 23:1605-1611
The presence of tangles of abnormally phosphorylated tau is a characteristic of Alzheimer's disease (AD), and the loss of synapses correlates with the degree of dementia. In addition, the overexpression of interleukin-1 (IL-1) has been implicated in
S100β Increases Levels of β-Amyloid Precursor Protein and Its Encoding mRNA in Rat Neuronal Cultures
Autor:
W. Sue T. Griffin, Steven W. Barger, Richard A. Jones, Robert E. Mrak, Ling Liu, J. G. Sheng, Jianzhong Wang, Yuekui Li, Linda J. Van Eldik
Publikováno v:
Journal of Neurochemistry. 71:1421-1428
S100beta has been implicated in the formation of dystrophic neurites, overexpressing beta-amyloid precursor protein (betaAPP), in the beta-amyloid plaques of Alzheimer's disease. We assessed the effects of S100beta on cell viability of, neurite outgr
Publikováno v:
Journal of Neurochemistry. 74:143-150
Levels of the neurotrophic cytokine S100beta and the proinflammatory cytokine interleukin-6 (IL-6) are both elevated in Alzheimer's brain, and both have been implicated in beta-amyloid plaque formation and progression. We used RT-PCR and electrophore
Publikováno v:
Zhonghua bing li xue za zhi = Chinese journal of pathology. 33(5)
To assess the relationship between microglia activation and apoptosis of neurons, and the significance of activated microglias in the formation and progression of senile plaques in Alzheimer's disease.IL-1alpha and beta-amyloid immunohistochemistry,
Publikováno v:
Journal of neuroscience research. 66(2)
Neurotoxic microglial-neuronal interactions have been implicated in the pathogenesis of various neurodegenerative diseases such as Alzheimer's disease, and vitamin E has been shown to have direct neuroprotective effects. To determine whether vitamin
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 20(1)
Cholinergic dysfunction in Alzheimer's disease has been attributed to stress-induced increases in acetylcholinesterase (AChE) activity. Interleukin-1 (IL-1) is overexpressed in Alzheimer's disease, and stress-related changes in long-term potentiation
Publikováno v:
Journal of Neuroinflammation; 2006, Vol. 3, p5-9, 9p, 6 Graphs
Publikováno v:
Journal of Neurochemistry; Feb2005, Vol. 92 Issue 3, p546-553, 8p