Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Yuejun Xiang"'
Autor:
Yuejun Xiang, Raymond F. Schinazi, Yung-Chi Cheng, Chung K. Chu, Socrates C. H. Cavalcanti, M. G. Newton
Publikováno v:
Nucleosides and Nucleotides. 18:2233-2252
A series of 2′,3′-dideoxy-2′-fluoro-L-threo-pentofuranosyl nucleosides has been synthesized as potential antiviral agents. The synthesized compounds were evaluated against HIV-1, HBV, HSV-1, and HSV-2. Among the synthesized analogues, only the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d46e38fb2ef6f72a76053c601d1be32
https://doi.org/10.1080/07328319908044878
https://doi.org/10.1080/07328319908044878
Publikováno v:
Nucleosides and Nucleotides. 15:1821-1834
Abstract: 2′,3′-Dideoxy-D-C-nucleosides, 2,4-diamino-5-(2,3-dideoxy-D-glycero-pentofuranosyl)pyrimidine.s (11 and 12), 4-amino-8-(2,3-dideoxy-D-glyceropentofuranosyl)pyrazolo[1,5-a]-1,3,5-triazines (17 and 18), 4-amino-7-(2,3-dideoxy-D-glyceropen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::069397ddb66bdddb4442cd47ac9ac7b4
https://doi.org/10.1080/07328319608002735
https://doi.org/10.1080/07328319608002735
Publikováno v:
Tetrahedron Letters. 37:4877-4880
A diastereo- and enantioselective synthesis of isoxazolidinyl nucleosides (4) is described. The required isoxazolidine intermediate (16) was successfully prepared by the dioxolane-derived tautomerization of the corresponding lactol (13) which, in tur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20ad2ee0d4846e01b1f8594a26993c44
https://doi.org/10.1016/0040-4039(96)00999-9
https://doi.org/10.1016/0040-4039(96)00999-9
Publikováno v:
Tetrahedron Letters. 36:3781-3784
Novel C-nucleosides (2′R,4′S)-and (2′S,4′R)-2-[4-(hydroxymethyl)-1,3-dioxolan-2-yl]-1,3-thiazole-4-carboxamide have been synthesized from stereoselectively induced condensation of optically active triols (S or R) with a 1,3-thiazole-4-carboxa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b26a4776ab3fc46994ac76efad3986b
https://doi.org/10.1016/0040-4039(95)00625-m
https://doi.org/10.1016/0040-4039(95)00625-m
Autor:
Yuejun Xiang, Yung-Chi Cheng, Young-Lian Zhu, Raymond F. Schinazi, S. Balakrishna Pai, Socrates C. H. Cavalcanti, Chung K. Chu
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:877-880
1-or-9-(2,3-Dideoxy-2-fluoro-β-L-threo-pentofuranosyl)- cytosine (F-β-L-ara-ddC) and-adenine (F-β-L-ara-ddA) were synthesized and their anti-HIV and anti-HBV activities were evaluated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e2e4b4ca9ca0ff3257eb0d0290d474a
https://doi.org/10.1016/0960-894x(95)00133-e
https://doi.org/10.1016/0960-894x(95)00133-e
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:743-748
1- or 9-(2-Deoxy-2,2-difluoro-β-L-ribofuranosyl)-thymine, -cytosine and -adenine were synthesized and their in vitro activity against HIV were evaluated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3314f9447233d1359dd6eb9d6feb920d
https://doi.org/10.1016/0960-894x(95)00107-5
https://doi.org/10.1016/0960-894x(95)00107-5
Publikováno v:
Journal of Fluorine Chemistry. 63:151-155
A novel one-pot synthesis of functionalized perfluoroalkylated 1,4-alkadienes via the Reformatsky reaction of unsaturated halo esters with fluorinated β-ketophosphonium salts is described. This new methodology provides a four-carbon homologation giv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::645e20b255f395f2ebc92a1f934fad85
https://doi.org/10.1016/s0022-1139(00)80405-4
https://doi.org/10.1016/s0022-1139(00)80405-4
Autor:
Yanchang Shen, Yuejun Xiang
Publikováno v:
ChemInform. 22
A new convenient one-pot synthesis of fluorinated bromoallenes starting from the commercial available substances is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33f0f561e17ed6aa6ebe83d7a4d2dcf7
https://doi.org/10.1002/chin.199126143
https://doi.org/10.1002/chin.199126143
Autor:
Yanchang Shen, Yuejun Xiang
Publikováno v:
ChemInform. 23
Trifluoromethylated β,γ-unsaturated esters and nitriles can be synthesized by reaction of organozinc compounds with fluorinated β-ketophosphonium salts. This novel reaction without isolation of intermediates provides a convenient synthesis of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fc732611147315dc7a59990b59913de
https://doi.org/10.1002/chin.199206132
https://doi.org/10.1002/chin.199206132
Autor:
Yanchang Shen, Yuejun Xiang
Publikováno v:
ChemInform. 23
4-Trifluoromethyl-2,4-dienamides can be successfully synthesized by the reaction of trifluoromethylated arsoranes, generated from the transylidation between fluorinated β-oxoalkylphosphonium salts and methylenetriphenylarsorane, with α-bromoacetami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fb0e816abd99fa4de9990041d2b2f0a
https://doi.org/10.1002/chin.199202150
https://doi.org/10.1002/chin.199202150