Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Yuejie Chen"'
Publikováno v:
Cells, Vol 12, Iss 22, p 2613 (2023)
STIM1 has been identified as a new warm sensor, but the exact molecular mechanism remains unclear. In this study, a variety of mutants of STIM1, Orai1 and Orai3 were generated. The single–cell calcium imaging and confocal analysis were used to eval
Externí odkaz:
https://doaj.org/article/0663625934af408781998afdec2f3cb1
Publikováno v:
Electronics
Volume 12
Issue 5
Pages: 1221
Volume 12
Issue 5
Pages: 1221
Photovoltaic Agriculture (PA) is a new management system combining industry with modern agriculture that can effectively reduce the competition for limited land resource usage between electric power production and agricultural production. However, PA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::987d11adc779cebceca96aa59bb5b7ae
https://eprints.lincoln.ac.uk/id/eprint/53626/1/23_PhotovoltaicAg.pdf
https://eprints.lincoln.ac.uk/id/eprint/53626/1/23_PhotovoltaicAg.pdf
Publikováno v:
R Journal; Dec2021, Vol. 13 Issue 2, p239-252, 14p
Autor:
Shan Wang, Peter Serno, Wouter Tonnis, Huijun Chen, Feng Qian, Linc Chen, Yipshu Pui, Yuejie Chen
Publikováno v:
Molecular Pharmaceutics. 16:205-213
We investigated the drug-polymer interactions in nonaqueous and aqueous environments between a poorly water-soluble drug, BAY1161909 (909), and two commonly used polymers in amorphous solid dispersions, i.e., PVP and HPMC-AS. In an nonaqueous state,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f68fce757d5eb1bd142684480dd32b
https://doi.org/10.1021/acs.molpharmaceut.8b00947
https://doi.org/10.1021/acs.molpharmaceut.8b00947
Autor:
Huijun Chen, Wouter Tonnis, Linc Chen, Shan Wang, Peter Serno, Stefan Bracht, Feng Qian, Chengyu Liu, Yipshu Pui, Yuejie Chen
Publikováno v:
Molecular Pharmaceutics. 15:2754-2763
Amorphous solid dispersion (ASD) is one of the most versatile supersaturating drug delivery systems to improve the dissolution rate and oral bioavailability of poorly water-soluble drugs. PVP based ASD formulation of nimodipine (NMD) has been markete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e9c35638434e55cb18e1930f31b036
https://doi.org/10.1021/acs.molpharmaceut.8b00253
https://doi.org/10.1021/acs.molpharmaceut.8b00253
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 124:73-81
The aim of this paper was to compare the in vitro dissolution and in vivo bioavailability of three solubility enhancement technologies for β-lapachone (LPC), a poorly water soluble compound with extremely high crystallization propensity. LPC cocryst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8ff7d2fb3dd6a581dc56aa334efa1dd
https://doi.org/10.1016/j.ejpb.2017.12.016
https://doi.org/10.1016/j.ejpb.2017.12.016
Publikováno v:
Pharmaceutical research. 36(7)
To reveal the underlying mechanism inducing the opposite trends of surface composition enrichment of spray dried amorphous solid dispersions (ASD) of sorafenib and regorafenib, two compounds only differ in hydrogen to fluorine substitution. Sorafenib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::056ff6edaad5f7b2ef3ff886c168c539
https://pubmed.ncbi.nlm.nih.gov/31102031
https://pubmed.ncbi.nlm.nih.gov/31102031
Publikováno v:
Molecular Pharmaceutics. 13:599-608
Sorafenib is a clinically important oral tyrosine kinase inhibitor for the treatment of various cancers. However, the oral bioavailability of sorafenib tablet (Nexavar) is merely 38-49% relative to the oral solution, due to the low aqueous solubility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f07cbe6cf7b1603412698b45b417ab99
https://doi.org/10.1021/acs.molpharmaceut.5b00837
https://doi.org/10.1021/acs.molpharmaceut.5b00837
Publikováno v:
Chemistry of Natural Compounds. 53:196-198
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fc895de017f7852ce3082f926ea57cc
https://doi.org/10.1007/s10600-017-1949-8
https://doi.org/10.1007/s10600-017-1949-8
Publikováno v:
Molecular pharmaceutics. 15(10)
Hydroxypropyl methylcellulose acetate succinate (HPMC-AS) is one of the commonly selected polymers used in amorphous solid dispersions (ASD) with excellent capabilities to maintain aqueous supersaturation of poorly water-soluble drugs and inhibit the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca1406dbafbda146d2bcad7d9afd003
https://pubmed.ncbi.nlm.nih.gov/30130968
https://pubmed.ncbi.nlm.nih.gov/30130968