Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yuejiao Zou"'
Autor:
Kevin J. Haworth, George L Britton, Shaoling Huang, Eva Golunski, Yuejiao Zou, David D. McPherson, Tao Peng, Melvin E. Klegerman, Ali Naji, Christy K. Holland
Publikováno v:
Journal of Liposome Research. 26:47-56
Bevacizumab (BEV) is a monoclonal antibody to vascular endothelial growth factor (VEGF) that ameliorates atheroma progression by inhibiting neovascularization.We aimed to determine whether BEV release from echogenic liposomes (BEV-ELIP) could be enha
Publikováno v:
Journal of liposome research. 24(3)
Thermodynamic analysis of ligand-target binding has been a useful tool for dissecting the nature of the binding mechanism and, therefore, potentially can provide valuable information regarding the utility of targeted formulations. Based on a consiste
Autor:
Melvin E Klegerman, Yuejiao Zou, George L Britton, Ali K Naji, Shao-Ling Huang, David D McPherson
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 32
Introduction. Bevacizumab (BEV) is a humanized monoclonal antibody to vascular endothelial growth factor (VEGF) that can ameliorate atheroma progression, the mechanism of which is believed to be through inhibition of neovascularization. Systemically,
Autor:
Chen Min Yang, Duane C. Kraemer, Christy K. Holland, Yuejiao Zou, Xinyi Ge, Yong-Jian Geng, Hyunggun Kim, Stephanie M. Herbst, Shaoling Huang, Michael Wassler, David D. McPherson, Jonathan A. Kopechek, Jiangbo Qi, Melvin E. Klegerman, Harnath Shelat, Melanie R. Moody, Fred J. Clubb
Publikováno v:
Molecular pharmaceutics. 7(1)
In atherosclerosis, the loss of vascular stem cells via apoptosis impairs the capacity of the vascular wall to repair or regenerate the tissue damaged by atherogenic factors. Recruitment of exogenous stem cells to the plaque tissue may repopulate vas
Autor:
Melvin E. Klegerman, Michael Wassler, Hyunggun Kim, Christy K. Holland, Yong-Jian Geng, Yuejiao Zou, Harnath Shelat, Shaoling Huang, David D. McPherson
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 142(3)
Intrinsically echogenic liposomes (ELIP) can be adapted to encapsulate nitric oxide to facilitate ultrasound-enhanced delivery of therapeutic agents to atherosclerotic plaques. However, the NO loading of targeted ELIP caused a 93% decrease of antibod
Publikováno v:
Journal of liposome research. 18(2)
Fibrin-specific molecular targeting strategies are desirable for site-specific imaging and treatment of late stage atheroma, but fibrin-specific antibodies are difficult to produce and present immunogenicity problems. Tissue plasminogen activator (tP
Autor:
Melanie Moody, Susan T Laing, Shaoling Huang, Hyunggun Kim, Beverly Smulevitz, Yuejiao Zou, David D McPherson, Melvin E Klegerman
Publikováno v:
Circulation. 116
Background: Ultrasound has been shown to enhance thrombolysis when used in conjunction with a thrombolytic agent. We have loaded echogenic liposomes (ELIP) with tissue plasminogen activator (tPA) and shown that mechanical non-imaging 1 MHz ultrasound
Publikováno v:
Chembiochem : a European journal of chemical biology. 8(17)