Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Yuehan, He"'
Publikováno v:
Zhongguo gonggong weisheng, Vol 40, Iss 8, Pp 948-953 (2024)
ObjectiveTo understand the chronic disease comorbidities among middle-aged and elderly Chinese population with different depression levels and provide a scientific basis for optimizing depression screening and chronic disease prevention and treatment
Externí odkaz:
https://doaj.org/article/830441df8ce645c59db76a0e94cf089b
Autor:
Xu Wang, Shibin Sun, Hongwei Chen, Bei Yun, Zihan Zhang, Xiaoxi Wang, Yifan Wu, Junjie Lv, Yuehan He, Wan Li, Lina Chen
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionCocaine is a highly addictive drug that is abused due to its excitatory effect on the central nervous system. It is critical to reveal the mechanisms of cocaine addiction and identify key genes that play an important role in addiction.Met
Externí odkaz:
https://doaj.org/article/f39ff32f9ca54f6083fedd1cc165ce3e
Autor:
Zherou Rong, Hongwei Chen, Zihan Zhang, Yue Zhang, Luanfeng Ge, Zhengyu Lv, Yuqing Zou, Junjie Lv, Yuehan He, Wan Li, Lina Chen
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-15 (2022)
Abstract Background Cardiomyopathy is a complex type of myocardial disease, and its incidence has increased significantly in recent years. Dilated cardiomyopathy (DCM) and ischemic cardiomyopathy (ICM) are two common and indistinguishable types of ca
Externí odkaz:
https://doaj.org/article/ff8e204eb1cf466faf1dc28a9d6cdbb9
Autor:
Wan Li, Yihua Zhang, Yahui Wang, Zherou Rong, Chenyu Liu, Hui Miao, Hongwei Chen, Yuehan He, Weiming He, Lina Chen
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Identifying or prioritizing genes for chronic obstructive pulmonary disease (COPD), one type of complex disease, is particularly important for its prevention and treatment. Methods In this paper, a novel method was proposed to Pri
Externí odkaz:
https://doaj.org/article/0a6c2fd85f7441ba9bbde0375ee62547
Autor:
Hongwei Chen, Zherou Rong, Luanfeng Ge, Hongzheng Yu, Chao Li, Manyi Xu, Zihan Zhang, Junjie Lv, Yuehan He, Wan Li, Lina Chen
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Stomach, liver, and colon cancers are the most common digestive system cancers leading to mortality. Cancer leader genes were identified in the current study as the genes that contribute to tumor initiation and could shed light on the molecular mecha
Externí odkaz:
https://doaj.org/article/052d663b8ba74b31a599511c0cdc4dec
Autor:
Kun Huang, Erqiang Hu, Wan Li, Junjie Lv, Yuehan He, Gui Deng, Jinling Xiao, Chengcheng Yang, Xinyu Zhao, Lina Chen, Xinyan Wang
Publikováno v:
BMC Medical Genetics, Vol 20, Iss 1, Pp 1-8 (2019)
Abstract Background Lung cancer is a leading cause of death from cancer worldwide, especially non-small cell lung cancer (NSCLC). The marker of progression in lung adenocarcinoma, the main type of NSCLC, has been rarely studied. Programmed death 1 (P
Externí odkaz:
https://doaj.org/article/b4eb248da7174ad2ae72836051a4e0c9
Autor:
Lei Fu, Kai Luo, Junjie Lv, Xinyan Wang, Shimei Qin, Zihan Zhang, Shibin Sun, Xu Wang, Bei Yun, Yuehan He, Weiming He, Wan Li, Lina Chen
Publikováno v:
Biology, Vol 11, Iss 9, p 1291 (2022)
Lung adenocarcinoma is the most common type of primary lung cancer, but the regulatory mechanisms during carcinogenesis remain unclear. The identification of regulatory modules for lung adenocarcinoma has become one of the hotspots of bioinformatics.
Externí odkaz:
https://doaj.org/article/9f78004c4d234e1590c319b30fa26a45
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184299 (2017)
Chronic obstructive pulmonary disease (COPD) is a multi-factor disease, in which metabolic disturbances played important roles. In this paper, functional information was integrated into a COPD-related metabolic network to assess similarity between ge
Externí odkaz:
https://doaj.org/article/81080ed55def48c6addab3432569a703
Autor:
Jing Jiang, Wan Li, Binhua Liang, Ruiqiang Xie, Binbin Chen, Hao Huang, Yiran Li, Yuehan He, Junjie Lv, Weiming He, Lina Chen
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153006 (2016)
Identifying the genes involved in venous thromboembolism (VTE) recurrence is important not only for understanding the pathogenesis but also for discovering the therapeutic targets. We proposed a novel prioritization method called Function-Interaction
Externí odkaz:
https://doaj.org/article/88f98f13b6cf43d787c77b6717f5df68
Autor:
Shimei Qin, Wan Li, Hongzheng Yu, Manyi Xu, Chao Li, Lei Fu, Shibin Sun, Yuehan He, Junjie Lv, Weiming He, Lina Chen
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 2244
Volume 24
Issue 3
Pages: 2244
Drug repositioning aims to discover novel clinical benefits of existing drugs, is an effective way to develop drugs for complex diseases such as cancer and may facilitate the process of traditional drug development. Meanwhile, network-based computati