Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Yueh-Hsiu Chien"'
Autor:
Chris Fleming, Yihua Cai, Xuan Sun, Venkatakrishna R. Jala, Feng Xue, Samantha Morrissey, Yu-ling Wei, Yueh-hsiu Chien, Huang-ge Zhang, Bodduluri Haribabu, Jian Huang, Jun Yan
Publikováno v:
Microbiome, Vol 5, Iss 1, Pp 1-15 (2017)
Abstract Background IL-17-producing γδT cells (γδT17) promote autoinflammatory diseases and cancers. Yet, γδT17 peripheral regulation has not been thoroughly explored especially in the context of microbiota-host interaction. The potent antigen-
Externí odkaz:
https://doaj.org/article/2af8dd2411fc4307a77909b8a3a6a2e5
Autor:
M Patricia D'Souza, Erin Adams, John D Altman, Michael E Birnbaum, Cesar Boggiano, Giulia Casorati, Yueh-Hsiu Chien, Anthony Conley, Sidonia Barbara Guiomar Eckle, Klaus Früh, Timothy Gondré-Lewis, Namir Hassan, Huang Huang, Lakshmi Jayashankar, Anne G Kasmar, Nina Kunwar, Judith Lavelle, David M Lewinsohn, Branch Moody, Louis Picker, Lakshmi Ramachandra, Nilabh Shastri, Peter Parham, Andrew J McMichael, Jonathan W Yewdell
Publikováno v:
PLoS Pathogens, Vol 15, Iss 2, p e1007567 (2019)
Most studies of T lymphocytes focus on recognition of classical major histocompatibility complex (MHC) class I or II molecules presenting oligopeptides, yet there are numerous variations and exceptions of biological significance based on recognition
Externí odkaz:
https://doaj.org/article/cc3b6392d68c4db2b0fca2712a8da0c6
Autor:
Xun Zeng, Christina Meyer, Jun Huang, Evan W Newell, Brian A Kidd, Yu-Ling Wei, Yueh-hsiu Chien
Publikováno v:
eLife, Vol 3 (2014)
The ability to recognize small organic molecules and chemical modifications of host molecules is an essential capability of the adaptive immune system, which until now was thought to be mediated mainly by B cell antigen receptors. Here we report that
Externí odkaz:
https://doaj.org/article/610da4d5602a4458b47aa45b65480e32
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67624 (2013)
High-throughput measurement of gene-expression and immune receptor repertoires have recently become powerful tools in the study of adaptive immune response. However, despite their now-widespread use, both tend to discard cell identity by treating cel
Externí odkaz:
https://doaj.org/article/9ad0b672cca346fdb29e1ac743724a84
Autor:
Laura M McLaughlin, Gregory R Govoni, Christiane Gerke, Smita Gopinath, Kaitian Peng, Grace Laidlaw, Yueh-Hsiu Chien, Ha-Won Jeong, Zhigang Li, Matthew D Brown, David B Sacks, Denise Monack
Publikováno v:
PLoS Pathogens, Vol 5, Iss 11, p e1000671 (2009)
Host-adapted strains of Salmonella enterica cause systemic infections and have the ability to persist systemically for long periods of time despite the presence of a robust immune response. Chronically infected hosts are asymptomatic and transmit dis
Externí odkaz:
https://doaj.org/article/367bb03163aa44459e43c6b2c8cd1f6a
Autor:
Roshni Roy Chowdhury, Jessica D’Addabbo, Xianxi Huang, Stefan Veizades, Koki Sasagawa, David M. Louis, Paul Cheng, Jan Sokol, Annie Jensen, Alexandria Tso, Vishnu Shankar, Ben Shogo Wendel, Isaac Bakerman, Grace Liang, Tiffany Koyano, Robyn Fong, Allison N. Nau, Herra Ahmad, Jayakrishnan Gopakumar, Robert Wirka, Andrew S. Lee, Jack Boyd, Y. Joseph Woo, Thomas Quertermous, Gunsagar Singh Gulati, Siddhartha Jaiswal, Yueh-Hsiu Chien, Charles Kwok Fai Chan, Mark M. Davis, Patricia K. Nguyen
Publikováno v:
Circ Res
Background:Coronary artery disease is an incurable, life-threatening disease that was once considered primarily a disorder of lipid deposition. Coronary artery disease is now also characterized by chronic inflammation‚ notable for the buildup of at
Autor:
Roshni Roy Chowdhury, John R. Valainis, Megha Dubey, Lotta von Boehmer, Elsa Sola, Julie Wilhelmy, Jing Guo, Oliver Kask, Mane Ohanyan, Meng Sun, Huang Huang, Xianxi Huang, Patricia K. Nguyen, Thomas J. Scriba, Mark M. Davis, Sean C. Bendall, Yueh-hsiu Chien
Publikováno v:
Science Immunology. 8
The response of gamma delta (γδ) T cells in the acute versus chronic phases of the same infection is unclear. How γδ T cells function in acute Mycobacterium tuberculosis (Mtb) infection is well characterized, but their response during persistent
Autor:
Qian Yin, Wei Luo, Vamsee Mallajosyula, Yang Bo, Jing Guo, Jinghang Xie, Meng Sun, Rohit Verma, Chunfeng Li, Christian M. Constantz, Lisa E. Wagar, Jing Li, Elsa Sola, Neha Gupta, Chunlin Wang, Oliver Kask, Xin Chen, Xue Yuan, Nicholas C. Wu, Jianghong Rao, Yueh-hsiu Chien, Jianjun Cheng, Bali Pulendran, Mark M. Davis
Publikováno v:
Nature materials, vol 22, iss 3
The ideal vaccine against viruses such as influenza and SARS-CoV-2 must provide a robust, durable and broad immune protection against multiple viral variants. However, antibody responses to current vaccines often lack robust cross-reactivity. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c9e5a2894f2a6f1915187af816bf497
https://escholarship.org/uc/item/7gc737gh
https://escholarship.org/uc/item/7gc737gh
Autor:
Stefan Veizades, Annie Jensen, Alexandria Tso, Xianxi Huang, Jessica D'addabbo, Yueh-hsiu Chien, Roshni Roy Chowdhury, Charles Chan, Mark Davis, Patricia Nguyen
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Background: The atherosclerotic plaque is a complex niche composed of immune cells including T cells and macrophages as well as vascular smooth muscle cells. How T cells interact with the plaque microenvironment is not well understood. Objective: To
Autor:
Annie Jensen, Stefan Veizades, Alexandria Tso, Koki Sasagawa, Jessica D'Addabbo, Xianxi Huang, Yueh-hsiu Chien, Roshni Roy Chowdhury, Charles Chan, Mark Davis, Patricia Nguyen
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Background: Atherosclerosis is considered a chronic inflammatory disorder characterized by the presence of T cells and macrophages in the plaque. Given that T cells are the master regulators of the immune system, the possible role of T cells in media