A nanofiber-hydrogel composite improves tissue repair in a rat model of Crohn's disease perianal fistulas

Autor: Ling Li, Zhi-Cheng Yao, Alyssa Parian, Yueh-Hsun Yang, Jeffrey Chao, Jason Yin, Kevan J. Salimian, Sashank K. Reddy, Atif Zaheer, Susan L. Gearhart, Hai-Quan Mao, Florin M. Selaru

Publikováno v: Science advances. 9(1)

Perianal fistulas (PAFs) represent a severe complication of Crohn’s disease (CD). Despite the advent of biologic and small-molecule therapeutics for luminal disease, PAFs in CD (CD-PAF) are relatively resistant to treatment, with less than 50% resp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e7282e11763e5cd9701cb17cd63a37
https://pubmed.ncbi.nlm.nih.gov/36598982

Theoretical evidence of osteoblast self-inhibition after activation of the genetic regulatory network controlling mineralization

Autor: Abdennasser Chekroun, Laurent Pujo-Menjouet, Steve Falcoz, Kamyine Tsuen, Kevin Yueh-Hsun Yang, Jean-Philippe Berteau

Publikováno v: Journal of Theoretical Biology
Journal of Theoretical Biology, 2022, 537, pp.111005. ⟨10.1016/j.jtbi.2022.111005⟩

International audience; Bone is a hard-soft biomaterial built through a self-assembly process under genetic regulatory network (GRN) monitoring. This paper aims to capture the behaviour of the bone GRN part that controls mineralization by using a mat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fc7c31179111098da18d30cb4bad7a9
https://doi.org/10.1016/j.jtbi.2022.111005

Theoretical evidence of osteoblast self-inhibition after activation of the genetic regulatory network controlling mineralization.

Autor: Chekroun A; Laboratoire d'Analyse Non Linéaire et Mathématiques Appliquées, University of Tlemcen, Chetouane 13000, Algeria; Univ Lyon, Inria, Université Claude Bernard Lyon 1, CNRS UMR5208, Institut Camille Jordan, F-69603 Villeurbanne, France., Pujo-Menjouet L; Univ Lyon, Inria, Université Claude Bernard Lyon 1, CNRS UMR5208, Institut Camille Jordan, F-69603 Villeurbanne, France. Electronic address: pujo@math.univ-lyon1.fr., Falcoz S; Univ Lyon, Inria, Université Claude Bernard Lyon 1, CNRS UMR5208, Institut Camille Jordan, F-69603 Villeurbanne, France; Department of Physical Therapy, College of Staten Island, City University of New York, New York, NY 10314, USA., Tsuen K; Department of Physical Therapy, College of Staten Island, City University of New York, New York, NY 10314, USA; Nanoscience Initiative, Advance Science Research Center, City University of New York, New York, NY 10031, USA., Yueh-Hsun Yang K; New York Center for Biomedical Engineering, City College of New York, City University of New York, New York, NY 10031, USA., Berteau JP; Department of Physical Therapy, College of Staten Island, City University of New York, New York, NY 10314, USA; New York Center for Biomedical Engineering, City College of New York, City University of New York, New York, NY 10031, USA; Nanoscience Initiative, Advance Science Research Center, City University of New York, New York, NY 10031, USA.

Publikováno v: Journal of theoretical biology [J Theor Biol] 2022 Mar 21; Vol. 537, pp. 111005. Date of Electronic Publication: 2022 Jan 12.

Neurite extension and neuronal differentiation of human induced pluripotent stem cell derived neural stem cells on polyethylene glycol hydrogels containing a continuous Young's Modulus gradient

Autor: Matthew C, Mosley, Hyun Ju, Lim, Jing, Chen, Yueh-Hsun, Yang, Shenglan, Li, Ying, Liu, Laura A, Smith Callahan

Publikováno v: Journal of biomedical materials research. Part A. 105(3)

Mechanotransduction in neural cells involves multiple signaling pathways that are not fully understood. Differences in lineage and maturation state are suggested causes for conflicting reports on neural cell mechanosensitivity. To optimize matrices f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0b24327a9a1b500a1a64da24937d798d
https://pubmed.ncbi.nlm.nih.gov/27798956

Coculture-Driven Mesenchymal Stem Cell-Differentiated Articular Chondrocyte-Like Cells Support Neocartilage Development

Autor: Gilda A. Barabino, Yueh Hsun Yang, Anna J. Lee

Controlled differentiation of mesenchymal stem cells (MSCs) into the chondrogenic lineage is crucial for in vitro generation of neocartilage, yet achieving it remains challenging. Traditional protocols for MSC differentiation using exogenous inductiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2b73a96f1113c9859134c3035861ac5
https://europepmc.org/articles/PMC3659664/