Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Yuebao, Zhang"'
Autor:
Yonger Xue, Yuebao Zhang, Yichen Zhong, Shi Du, Xucheng Hou, Wenqing Li, Haoyuan Li, Siyu Wang, Chang Wang, Jingyue Yan, Diana D. Kang, Binbin Deng, David W. McComb, Darrell J. Irvine, Ron Weiss, Yizhou Dong
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Adipose stem cells (ASCs) have attracted considerable attention as potential therapeutic agents due to their ability to promote tissue regeneration. However, their limited tissue repair capability has posed a challenge in achieving optimal t
Externí odkaz:
https://doaj.org/article/625c5a8ddd304299b6fd4d928fdfa3a5
Autor:
Shi Du, Wenqing Li, Yuebao Zhang, Yonger Xue, Xucheng Hou, Jingyue Yan, Jeffrey Cheng, Binbin Deng, David W. McComb, Jennifer Lin, Hong Zeng, Xiaolin Cheng, Darrell J. Irvine, Ron Weiss, Yizhou Dong
Publikováno v:
Advanced Science, Vol 10, Iss 11, Pp n/a-n/a (2023)
Abstract Male infertility caused by genetic mutations is an important type of infertility. Currently, there is no reliable method in the clinic to address this medical need. The emergence of mRNA therapy provides a possible strategy for restoring mut
Externí odkaz:
https://doaj.org/article/9d73ad80650f478b8530e1d5629c2893
Autor:
Wenqing Li, Xinfu Zhang, Chengxiang Zhang, Jingyue Yan, Xucheng Hou, Shi Du, Chunxi Zeng, Weiyu Zhao, Binbin Deng, David W. McComb, Yuebao Zhang, Diana D. Kang, Junan Li, William E. Carson, Yizhou Dong
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Antibodies targeting OX40 or CD137, two T cell costimulatory receptors, have been shown to improve antitumor immunity. Here the authors design a phospholipid-derived nanoparticle to deliver OX40 or CD137 mRNA to T cells in vivo, improving efficacy of
Externí odkaz:
https://doaj.org/article/c560ecaa3fe24937b23b46640aec4f30
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 9, Pp 1589-1600 (2020)
Antibody drug conjugates (ADCs) normally compose of a humanized antibody and small molecular drug via a chemical linker. After decades of preclinical and clinical studies, a series of ADCs have been widely used for treating specific tumor types in th
Externí odkaz:
https://doaj.org/article/eb045b7f8a54444aa85851359421c9db
Autor:
Siyu Wang, Yuebao Zhang, Yichen Zhong, Yonger Xue, Zhengwei Liu, Chang Wang, Kang, Diana D., Haoyuan Li, Xucheng Hou, Meng Tian, Dinglingge Cao, Leiming Wang, Kaiyuan Guo, Binbin Deng, McComb, David W., Merad, Miriam, Brown, Brian D., Yizhou Dong
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 5/28/2024, Vol. 121 Issue 22, p1-10, 40p
Autor:
Yuebao Zhang, Jingyue Yan, Xucheng Hou, Chang Wang, Diana D. Kang, Yonger Xue, Shi Du, Binbin Deng, David W. McComb, Shan-Lu Liu, Yichen Zhong, Yizhou Dong
Publikováno v:
Nano Letters. 23:2593-2600
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db0a1f37f6f269111638aa32cdcc22ce
https://doi.org/10.1021/acs.nanolett.2c04883
https://doi.org/10.1021/acs.nanolett.2c04883
Autor:
Byungji, Kim, Ryan R, Hosn, Tanaka, Remba, Dongsoo, Yun, Na, Li, Wuhbet, Abraham, Mariane B, Melo, Manuel, Cortes, Bridget, Li, Yuebao, Zhang, Yizhou, Dong, Darrell J, Irvine
Publikováno v:
Journal of Controlled Release. 353:241-253
The recent clinical success of multiple mRNA-based SARS-CoV-2 vaccines has proven the potential of RNA formulated in lipid nanoparticles (LNPs) in humans, and products based on base-modified RNA, sequence-optimized RNA, and self-replicating RNAs form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a27996f51128028b14f168abfe074d
https://doi.org/10.1016/j.jconrel.2022.11.022
https://doi.org/10.1016/j.jconrel.2022.11.022
Publikováno v:
Chem Rev
RNA-based therapeutics have shown great promise in treating a broad spectrum of diseases through various mechanisms including knockdown of pathological genes, expression of therapeutic proteins, and programmed gene editing. Due to the inherent instab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7f5c9fb2b424e767de94053f8627704
https://doi.org/10.1021/acs.chemrev.1c00244
https://doi.org/10.1021/acs.chemrev.1c00244
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 10, Iss 9, Pp 1589-1600 (2020)
Acta Pharmaceutica Sinica B, Vol 10, Iss 9, Pp 1589-1600 (2020)
Antibody drug conjugates (ADCs) normally compose of a humanized antibody and small molecular drug via a chemical linker. After decades of preclinical and clinical studies, a series of ADCs have been widely used for treating specific tumor types in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f923086246188a78722c4de365bf79a5
https://doi.org/10.1016/j.apsb.2020.04.012
https://doi.org/10.1016/j.apsb.2020.04.012
Publikováno v:
Acc Chem Res
After decades of extensive fundamental studies and clinical trials, lipid nanoparticles (LNPs) have demonstrated effective mRNA delivery such as the Moderna and Pfizer-BioNTech vaccines fighting against COVID-19. Moreover, researchers and clinicians
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34b31b8778d68d470441bfb6f20f55a7
https://europepmc.org/articles/PMC10068911/
https://europepmc.org/articles/PMC10068911/
