Zobrazeno 1 - 10
of 24
pro vyhledávání: '"YueQiang Xue"'
Publikováno v:
Behavioural Brain Research. 292:83-94
Evidence has emerged suggesting that diet-induced obesity can have a negative effect on cognitive function. Here, we exploited a mouse genetic reference population to look for the linkage between these two processes on a genome-wide scale. The focus
Autor:
Ruishan Wang, YueQiang Xue, Shaoya Chen, Yingchun Liu, Shiyong Diao, Xiaoqing You, Francesca-Fang Liao, Edwards A. Park
Publikováno v:
Journal of Biological Chemistry. 290:22532-22542
Insulin resistance and neuroinflammation have emerged as two likely key contributors in the pathogenesis of Alzheimer disease (AD), especially in those sporadic AD cases compromised by diabetes or cardiovascular disease. Amyloid-β (Aβ) deposition a
Autor:
Ling-Qiang Zhu, Jing Jing Li, Francesca-Fang Liao, Bin Wang, Dan Liu, YueQiang Xue, Kazuko Sakata, Huaxi Xu, Yaomin Chen, Scott A. Heldt
Publikováno v:
The Journal of Neuroscience. 34:2464-2470
The excessive accumulation of soluble amyloid peptides (Aβ) plays a crucial role in the pathogenesis of Alzheimer's disease (AD), particularly in synaptic dysfunction. The role of the two major chaperone proteins, Hsp70 and Hsp90, in clearing misfol
Autor:
Keran Ma, Inma Cobos, YueQiang Xue, Jasna Jerecic, Kaitlyn Ho, Jorge J. Palop, Jean-Cosme Dodart, Abdullah S. Khan, Maria M. Martinez-Losa
Publikováno v:
Alzheimer's & Dementia. 15:P595-P595
Publikováno v:
European Journal of Neuroscience. 35:775-783
Continued cocaine use despite the negative consequences is a hallmark of cocaine addiction. One such consequence is punishment, which is often used by society to curb cocaine use. Unfortunately, we know little about the mechanism involved in regulati
Publikováno v:
Psychopharmacology. 220:75-85
A high rate of relapse is a daunting challenge facing clinical treatment of cocaine addiction. Recent studies have shown that drugs of abuse enhance glutamate neurotransmission in dopamine neurons in the ventral tegmental area (VTA) and such enhancem
Publikováno v:
European Journal of Neuroscience. 33:1291-1298
Relapse is a hallmark of cocaine addiction. Cocaine-induced neuroplastic changes in the mesocorticolimbic circuits critically contribute to this phenomenon. Preclinical evidence indicates that relapse to cocaine-seeking behavior depends on activation
Publikováno v:
Genes, Brain and Behavior. 17:e12485
Enriched environment treatment (EET) is a potential intervention for depression by inducing brain-derived neurotrophic factor (BDNF). However, its age dependency remains unclear. We recently found that EET during early-life development (ED) was effec
Publikováno v:
Psychopharmacology. 210:179-188
Relapse is one of the main challenges facing the current treatment of cocaine addiction. Understanding its neurobiological mechanism is a critical step toward developing effective anti-relapse therapies.Emerging evidence indicates that glutamate-medi
Publikováno v:
Gene Therapy. 17:83-94
We have recently shown that intrastriatal injection of recombinant human erythropoietin (EPO) protects dopaminergic (DA) neurons in the substantia nigra (SN) from 6-hydroxydopamine (6-OHDA) toxicity in a rat model of Parkinson's disease. However, sys