Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Yue-Ze Liu"'
Publikováno v:
Neural Regeneration Research, Vol 10, Iss 10, Pp 1617-1621 (2015)
Geniposide, a monomer extracted from gardenia and widely used in Chinese medicine, is a novel agonist at the glucagon-like peptide-1 receptor. This receptor is involved in neuroprotection. In the present study, we sought to identify an anti-apoptotic
Externí odkaz:
https://doaj.org/article/b10a92efb0c8431285f463e0b7940b48
Publikováno v:
Neural Regeneration Research, Vol 11, Iss 2, Pp 0-0 (2016)
Externí odkaz:
https://doaj.org/article/595a8af622e54b64a573ce8b0c1badba
Publikováno v:
Neural Regeneration Research
Neural Regeneration Research, Vol 11, Iss 2, Pp 0-0 (2016)
Neural Regeneration Research, Vol 11, Iss 2, Pp 0-0 (2016)
The growth factor glucagon-like peptide-1 (GLP-1) is neuroprotective in several animal models of neurodegeneration. Here, we analyzed the neuroprotective effects of a novel protease-resistant GLP-1 analogue, (Val 8 )GLP-1-Glu-PAL, which has advantage
Publikováno v:
Neural Regeneration Research, Vol 10, Iss 10, Pp 1617-1621 (2015)
Neural Regeneration Research
Neural Regeneration Research
Geniposide, a monomer extracted from gardenia and widely used in Chinese medicine, is a novel agonist at the glucagon-like peptide-1 receptor. This receptor is involved in neuroprotection. In the present study, we sought to identify an anti-apoptotic
Publikováno v:
Brain Pathology. 24:261-269
Intracerebral-ventricular (ICV) injection of streptozotocin (STZ) induces an insulin-resistant brain state that may underlie the neural pathogenesis of sporadic Alzheimer disease (AD). Our previous work showed that prior ICV treatment of glucagon-lik
Publikováno v:
European Journal of Pharmacology. 674:280-286
It has being shown that glucagon-like peptide-1 (GLP-1), a new anti-diabetes agent, significantly attenuated beta-amyloid (Aβ) levels in rats. In the present study, (Val(8))GLP-1 was used to prevent impairments in memory formation, tau hyperphosphor
Publikováno v:
Biological Trace Element Research. 143:1581-1593
Elevated iron levels are considered to play a role in the neurodegenerative mechanisms that underlie Alzheimer's and Parkinson's disease. The linkage between hepcidin (Hepc) and ferroportin-1 (FPN1), the divalent metal transporter 1 (DMT1), and cerul
Publikováno v:
Reviews in the neurosciences. 24(6)
Alzheimer's disease (AD) is a complex neurodegenerative disorder, which involves many underlying pathological processes. Recently, it has been demonstrated that AD also includes impairments of insulin signaling in the brain. Type 2 diabetes is a risk
Publikováno v:
Reviews in the neurosciences. 23(1)
As a constitutively active kinase, glycogen synthase kinase 3 (GSK3) is a kinase which regulates body metabolism by phosphorylation of glycogen synthase (GS) and other substrates. Considerable evidence suggests that GSK3 is involved in the common pat
Publikováno v:
European journal of pharmacology. 674(2-3)
It has being shown that glucagon-like peptide-1 (GLP-1), a new anti-diabetes agent, significantly attenuated beta-amyloid (Aβ) levels in rats. In the present study, (Val(8))GLP-1 was used to prevent impairments in memory formation, tau hyperphosphor