Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Yue-Xin Lu"'
Autor:
Ling-Ping Zhao, Xiaozhan Wang, Yan Zhang, Yong Wang, Yue-Xin Lu, Zhi-Xiang Huang, Pi-Xiao Wang, Peng Zhang, Xiao-Jing Zhang, Yan-Xiao Ji, Feng Li, Zhi-Gang She, Zan Huang, Xueyong Zhu, Zhao Huan, Jun Gong, Mao-Mao Gao, Song Tian, David E. Cohen, Hongliang Li, Michele Alves-Bezerra, Xia Yang, Lin Cai, Lan Bai
Publikováno v:
Nature Medicine. 24:213-223
Nonalcoholic steatohepatitis (NASH) is a common clinical condition that can lead to advanced liver diseases. Lack of effective pharmacotherapies for NASH is largely attributable to an incomplete understanding of its pathogenesis. The deubiquitinase c
Autor:
Yan-Xiao Ji, Feng Li, Xin Zhang, Xia Yang, Xin-Liang Ma, Song Tian, Peng Zhang, Zhi-Gang She, Ling-Ping Zhao, Zan Huang, Yan Zhang, Jun Gong, Mao-Mao Gao, Hongliang Li, Yue-Xin Lu, Xiao-Jing Zhang, Pi-Xiao Wang, Zhihua Wang, Chun Fang, Xueyong Zhu
Publikováno v:
Nature Medicine. 24:84-94
Activation of apoptosis signal-regulating kinase 1 (ASK1) in hepatocytes is a key process in the progression of nonalcoholic steatohepatitis (NASH) and a promising target for treatment of the condition. However, the mechanism underlying ASK1 activati
Autor:
Zhi-Gang She, Ling Yang, Xiao-Jing Zhang, Kuo Zhang, Yue-Xin Lu, Xueyong Zhu, Ling-Ping Zhao, Rong Bao, Jilin Zheng, Li-Jun Shen, Yu Qi, Yi-Da Tang, Siyuan Wang, Shimin An
Publikováno v:
Hepatology. 66:1866-1884
Nonalcoholic fatty liver disease (NAFLD) is characterized by hepatic steatosis, impaired insulin sensitivity, and chronic low-grade inflammation. However, the pathogenic mechanism of NAFLD is poorly understood, which hinders the exploration of possib
Autor:
Yupeng Liu, Yi-Da Tang, Peng Sun, Yufeng Yuan, Xiaozhan Wang, Yue-Xin Lu, Daqing Cheng, Jilin Zheng, Kuo Zhang
Publikováno v:
Hepatology (Baltimore, Md.). 68(6)
Sterile inflammation is an essential factor causing hepatic ischemia/reperfusion (I/R) injury. As a critical regulator of inflammation, the role of monocyte chemoattractant protein-induced protein 1 (MCPIP1) in hepatic I/R injury remains undetermined