Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Yue-Xiang CHENG"'
Autor:
Yuri Frosi, Yen-Chu Lin, Jiang Shimin, Siti Radhiah Ramlan, Kelly Hew, Alf Henrik Engman, Anil Pillai, Kit Yeung, Yue Xiang Cheng, Tobias Cornvik, Par Nordlund, Megan Goh, Dilraj Lama, Zachary P. Gates, Chandra S. Verma, Dawn Thean, David P. Lane, Ignacio Asial, Christopher J. Brown
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
Approaches have been devised to increase the discovery rate of intrabodies but often these yield results that aren’t functional in cells. Here the authors engineer and optimise an autonomous and disulphide-free human VH domain for intracellular exp
Externí odkaz:
https://doaj.org/article/e93e759ee68a4352930b901a4ebc4c2b
Autor:
Yuri Frosi, Shimin Jiang, Siti Radhiah Ramlan, Kelly Hew Hew, Alf Henrik Engman, Anil Pillai, Yue Xiang Cheng, Tobias Cornvik, Pär Nordlund, Megan Goh, Dilraj Lama, Chandra S Verma, Dawn Thean Thean, David P Lane, Ignacio Asial, Christopher Brown
An attractive approach to target intracellular macromolecular interfaces is to design small high affinity proteins. In this manuscript a stable, autonomous, human derived non-immunogenic, disulphide-free VH domain, has been engineered for intracellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f80d30117a302deec2afff7f0e3fc6c
https://doi.org/10.21203/rs.3.rs-244469/v2
https://doi.org/10.21203/rs.3.rs-244469/v2
Autor:
Tobias Cornvik, Yue Xiang Cheng, Henrik Engman, Pär Nordlund, Maria Dollhopf, Ignacio Asial, Binghuang Wu
Protein stability is often a limiting factor in the development of commercial proteins and biopharmaceuticals, as well as for biochemical and structural studies. Unfortunately, identifying stabilizing mutations is not trivial since most are neutral o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a03363385ffeef135f92de955865675
http://hdl.handle.net/10220/19332
http://hdl.handle.net/10220/19332
Autor:
Chen LIU, Jian-Nong LU, Xue-Gui YIN, Chuan BI, Dan-You WEN, Jun ZHENG, Shuai LIU, Zhuo-Xing SHI, Yue-Xiang CHENG
Publikováno v:
Acta Agronomica Sinica. 40:751
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ff9a17139258f75a2223602fe25b903
https://doi.org/10.3724/sp.j.1006.2014.00751
https://doi.org/10.3724/sp.j.1006.2014.00751