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Publikováno v:
Journal of Food & Drug Analysis. Jan2018, Vol. 26 Issue 1, p422-431. 10p.
Publikováno v:
Journal of Food and Drug Analysis, Vol 26, Iss 1, Pp 422-431 (2018)
Hypericum perforatum [St. John’s wort (SJW)] is known to cause a drug interaction with the substrates of cytochrome P450 (P450, CYP) isoforms, mainly CYP3A. This study aims to determine the dose response and time course of the effects of SJW extrac