Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Yue-Kun Ju"'
Autor:
Georg Vogler, Diane Fatkin, Katja Birker, Christiana Leimena, Ann-Kristin Altekoester, Peter C. M. Molenaar, Karen Ocorr, David G. Allen, Richard P. Harvey, Halina Dobrzynski, Inken G. Huttner, Arie Jacoby, Magdalena Soka, Renee Johnson, Andrew Atkinson, Vesna Nikolova-Krstevski, Adam P. Hill, Rolf Bodmer, Yue-Kun Ju, Sreehari Kalvakuri, Santiago Pineda, Dirk F. van Helden, Charles D. Cox, Dennis L. Kuchar, Monique Ohanian, Gunjan Trivedi
Publikováno v:
Circulation: Genomic and Precision Medicine. 14
Background: KCNMA1 encodes the α-subunit of the large-conductance Ca 2+ -activated K + channel, K Ca 1.1, and lies within a linkage interval for atrial fibrillation (AF). Insights into the cardiac functions of K Ca 1.1 are limited, and KCNMA1 has no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01612d0422981dad9c335de2df839668
https://doi.org/10.1161/circgen.120.003144
https://doi.org/10.1161/circgen.120.003144
Autor:
Santiago, Pineda, Vesna, Nikolova-Krstevski, Christiana, Leimena, Andrew J, Atkinson, Ann-Kristin, Altekoester, Charles D, Cox, Arie, Jacoby, Inken G, Huttner, Yue-Kun, Ju, Magdalena, Soka, Monique, Ohanian, Gunjan, Trivedi, Sreehari, Kalvakuri, Katja, Birker, Renee, Johnson, Peter, Molenaar, Dennis, Kuchar, David G, Allen, Dirk F, van Helden, Richard P, Harvey, Adam P, Hill, Rolf, Bodmer, Georg, Vogler, Halina, Dobrzynski, Karen, Ocorr, Diane, Fatkin
Publikováno v:
Circ Genom Precis Med
BACKGROUND: KCNMA1 encodes the α-subunit of the large-conductance Ca(2+)-activated K(+) channel, K(Ca)1.1, and lies within a linkage interval for atrial fibrillation (AF). Insights into the cardiac functions of K(Ca)1.1 are limited, and KCNMA1 has n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::945820691bcdde1e027da6e9bb57eee1
https://pubmed.ncbi.nlm.nih.gov/33629867
https://pubmed.ncbi.nlm.nih.gov/33629867
Autor:
Santiago Pined, David G. Allen, Dirk F. van Helden, Sreehari Kalvakuri, Halina Dobrzyn, Christiana Leimena, Renee Johnson, Andrew Atkinson, Richard P. Harvey, Diane Fatkin, Gunjan Trived, Ann-Kristin Altekoester, Karen Ocorr, Peter C. M. Molenaar, Arie Jacoby, Charles D. Cox, Dennis L. Kuchar, Rolf Bodmer, Monique Ohanian, Inken G. Huttner, Georg Vogler, Magdalena Soka, Vesna Nikolova-Krstevski, Yue-Kun Ju, Adam P. Hill
BackgroundKCNMA1 encodes the α-subunit of the large-conductance Ca2+-activated K+ channel, KCa1.1, and lies within a linkage interval for atrial fibrillation (AF). Insights into the cardiac functions of KCa1.1 are limited and KCNMA1 has not been inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47d38efcb107ad676586738e523b836b
https://doi.org/10.1101/2020.06.28.176495
https://doi.org/10.1101/2020.06.28.176495
Publikováno v:
Journal of Molecular and Cellular Cardiology. 53:375-381
Intracellular Ca(2+) plays an important role in the control of the heart rate through the interaction between Ca(2+) release by ryanodine receptors in the sarcoplasmic reticulum (SR) and the extrusion of Ca(2+) by the sodium-calcium exchanger which g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a443dcb76d7a03083c5ccfab9e94386
https://doi.org/10.1016/j.yjmcc.2012.06.004
https://doi.org/10.1016/j.yjmcc.2012.06.004
Publikováno v:
Progress in Biophysics and Molecular Biology. 97:232-249
The stretch-induced increase in force production of ventricular muscle is biphasic. An abrupt increase in force coincides with the stretch, which is then followed by a slower response that develops over minutes (the slow force response or SFR). The S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b20297205c61e39af55d6d98f750c69b
https://doi.org/10.1016/j.pbiomolbio.2008.02.009
https://doi.org/10.1016/j.pbiomolbio.2008.02.009
Autor:
David G. Allen, Yue-Kun Ju
Publikováno v:
Heart, Lung and Circulation. 16:349-355
Store-operated Ca(2+) channels (SOCCs) were first identified in non-excitable cells by the observation that depletion of Ca(2+) stores caused increased influx of extracellular Ca(2+). Recent studies have suggested that SOCCs might be related to the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94da5651631ee250031c9c5078658101
https://doi.org/10.1016/j.hlc.2007.07.004
https://doi.org/10.1016/j.hlc.2007.07.004
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 454:903-912
Intracellular Na(+) concentration ([Na(+)](i)) rises in the heart during ischemia, and on reperfusion, there is a transient rise followed by a return toward control. These changes in [Na(+)](i) contribute to ischemic and reperfusion damage through th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea6262e606a41d5fb969d55c16ac517
https://doi.org/10.1007/s00424-007-0241-3
https://doi.org/10.1007/s00424-007-0241-3
Autor:
Mark B. Cannell, Bon Hyang Lee, Sofie Trajanovska, Ming Lei, David G. Allen, Gouliang Hao, Yue-Kun Ju
Publikováno v:
Frontiers in Physiology, Vol 6 (2015)
Frontiers in Physiology
Ju, Y-K, Lee, B H, Trajanovska, S, Hao, G, Allen, D G, Lei, M & Cannell, M B 2015, ' The involvement of TRPC3 channels in sinoatrial arrhythmias ', Frontiers in Physiology, vol. 6, 86 . https://doi.org/10.3389/fphys.2015.00086
Frontiers in Physiology
Ju, Y-K, Lee, B H, Trajanovska, S, Hao, G, Allen, D G, Lei, M & Cannell, M B 2015, ' The involvement of TRPC3 channels in sinoatrial arrhythmias ', Frontiers in Physiology, vol. 6, 86 . https://doi.org/10.3389/fphys.2015.00086
Atrial fibrillation (AF) is a significant contributor to cardiovascular morbidity and mortality. The currently available treatments are limited and AF continues to be a major clinical challenge. Clinical studies have shown that AF is frequently assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82c44fe64304bec0a7f86501ccfa608a
https://doi.org/10.3389/fphys.2015.00086
https://doi.org/10.3389/fphys.2015.00086
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 6 (2015)
Frontiers in Physiology, Vol 6 (2015)
In many non-excitable and excitable cells, store-operated calcium entry (SOCE) represents an additional pathway for calcium entry upon Ca(2+) store depletion. In a previous study, we demonstrated SOCE activity in intact mouse cardiac pacemaker tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2be9c97775d39bdc5aae0046344a7aaf
https://doi.org/10.3389/fphys.2015.00069
https://doi.org/10.3389/fphys.2015.00069
Autor:
David G. Allen, Yue-Kun Ju
Publikováno v:
Pfl�gers Archiv - European Journal of Physiology. 449:442-448
The effects of the metabolic inhibition on the activity of the Na+/Ca2+ exchanger (NCX) were studied in single isolated pacemaker cells from the cane toad. Ca2+ influx on NCX (reverse mode) was estimated by measuring the increase in intracellular cal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3634138957322c418f7fb49c53bd602
https://doi.org/10.1007/s00424-004-1334-x
https://doi.org/10.1007/s00424-004-1334-x