Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Yue-He D"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Piwi-interacting RNAs (piRNAs) are genomically encoded small RNAs that engage Piwi Argonaute proteins to direct mRNA surveillance and transposon silencing. Despite advances in understanding piRNA pathways and functions, how the production of
Externí odkaz:
https://doaj.org/article/b166c3f051054658856bf6dbb14a442a
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112408- (2023)
Summary: Argonaute/small RNA pathways and heterochromatin work together to propagate transgenerational gene silencing, but the mechanisms behind their interaction are not well understood. Here, we show that induction of heterochromatin silencing in C
Externí odkaz:
https://doaj.org/article/9736d36d55134e42911df4acf028d412
Autor:
Alexander X. Jones, Yong Cao, Yu-Liang Tang, Jian-Hua Wang, Yue-He Ding, Hui Tan, Zhen-Lin Chen, Run-Qian Fang, Jili Yin, Rong-Chang Chen, Xing Zhu, Yang She, Niu Huang, Feng Shao, Keqiong Ye, Rui-Xiang Sun, Si-Min He, Xiaoguang Lei, Meng-Qiu Dong
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Cross-linking mass spectrometry can provide insights into protein structures and interactions but its scope depends on the reactivity of the cross-linker. Here, the authors develop Arg-Arg and Lys-Arg cross-linkers, which provide structural informati
Externí odkaz:
https://doaj.org/article/a855dbbbf40242cb82962d2fa4fbde46
Autor:
Zhen-Lin Chen, Jia-Ming Meng, Yong Cao, Ji-Li Yin, Run-Qian Fang, Sheng-Bo Fan, Chao Liu, Wen-Feng Zeng, Yue-He Ding, Dan Tan, Long Wu, Wen-Jing Zhou, Hao Chi, Rui-Xiang Sun, Meng-Qiu Dong, Si-Min He
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
The identification of cross-linked peptides at a proteome scale for interactome analyses represents a complex challenge. Here the authors report an efficient and reliable search engine pLink 2 for proteome-scale cross-linking mass spectrometry analys
Externí odkaz:
https://doaj.org/article/5bf1da56fec7495f8b611bdf3f8aef38
Autor:
Heesun Kim, Yue-He Ding, Shan Lu, Mei-Qing Zuo, Wendy Tan, Darryl Conte Jr, Meng-Qiu Dong, Craig C Mello
Publikováno v:
eLife, Vol 10 (2021)
Germlines shape and balance heredity, integrating and regulating information from both parental and foreign sources. Insights into how germlines handle information have come from the study of factors that specify or maintain the germline fate. In ear
Externí odkaz:
https://doaj.org/article/71405efbad234aec9a6317f77a5bb199
Autor:
Heesun Kim, Yue-He Ding, Gangming Zhang, Yong-Hong Yan, Darryl Conte Jr, Meng-Qiu Dong, Craig C Mello
Publikováno v:
eLife, Vol 10 (2021)
Eukaryotic cells use guided search to coordinately control dispersed genetic elements. Argonaute proteins and their small RNA cofactors engage nascent RNAs and chromatin-associated proteins to direct transcriptional silencing. The small ubiquitin-lik
Externí odkaz:
https://doaj.org/article/710135ee04cb44519204f6333a1da809
Autor:
Jia-Min Zhang, Jin-Xin Zheng, Yue-He Ding, Xiao-Ran Zhang, Fang Suo, Jing-Yi Ren, Meng-Qiu Dong, Li-Lin Du
Publikováno v:
PLoS Genetics, Vol 16, Iss 7, p e1008933 (2020)
Structure-specific endonucleases (SSEs) play key roles in DNA replication, recombination, and repair. SSEs must be tightly regulated to ensure genome stability but their regulatory mechanisms remain incompletely understood. Here, we show that in the
Externí odkaz:
https://doaj.org/article/7473e6b355a04c4ab61fdab784307137
Autor:
Xiaolu Ma, Hongmei Liu, Jing Li, Yihao Wang, Yue-He Ding, Hongyan Shen, Yeran Yang, Chenyi Sun, Min Huang, Yingfeng Tu, Yang Liu, Yongliang Zhao, Meng-Qiu Dong, Ping Xu, Tie-Shan Tang, Caixia Guo
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Polη is a key player in translesion DNA synthesis. Here, the authors uncover that, in response to DNA damage, Polη undergoes O-GlcNAcylation at threonine 457 by O-GlcNAc transferase to facilitate the timely disassembly of Polη after DNA lesion byp
Externí odkaz:
https://doaj.org/article/599494d1f24f4a00a4388d28f4e28b0b
Autor:
Shengliu Wang, Yujia Zhai, Xiaoyun Pang, Tongxin Niu, Yue-He Ding, Meng-Qiu Dong, Victor W. Hsu, Zhe Sun, Fei Sun
Publikováno v:
Protein & Cell, Vol 7, Iss 8, Pp 586-600 (2016)
Abstract Studies on coat protein I (COPI) have contributed to a basic understanding of how coat proteins generate vesicles to initiate intracellular transport. The core component of the COPI complex is coatomer, which is a multimeric complex that nee
Externí odkaz:
https://doaj.org/article/450c245ef9694f7cbed96ae28caa6dad
Autor:
Dan Tan, Qiang Li, Mei-Jun Zhang, Chao Liu, Chengying Ma, Pan Zhang, Yue-He Ding, Sheng-Bo Fan, Li Tao, Bing Yang, Xiangke Li, Shoucai Ma, Junjie Liu, Boya Feng, Xiaohui Liu, Hong-Wei Wang, Si-Min He, Ning Gao, Keqiong Ye, Meng-Qiu Dong, Xiaoguang Lei
Publikováno v:
eLife, Vol 5 (2016)
To improve chemical cross-linking of proteins coupled with mass spectrometry (CXMS), we developed a lysine-targeted enrichable cross-linker containing a biotin tag for affinity purification, a chemical cleavage site to separate cross-linked peptides
Externí odkaz:
https://doaj.org/article/d1b4dc53824b43dfb9c0301bb08e8ae7