Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Yue-E. Wu"'
Autor:
Ben-Nian Huo, Yue-E. Wu, Ling Shu, Ruo-Qi Zhang, Jian-Wen Xiao, Qian-Bo Li, Wei Zhao, Yun-Tao Jia, Lin Song
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Objectives: There have been limited studies concerning the safety and efficacy of linezolid (LZD) in children. This study aimed to evaluate the association between LZD exposure and clinical safety and efficacy in Chinese pediatric patients.Methods: T
Externí odkaz:
https://doaj.org/article/84507ff3dc024dd98c98f137ca341689
Autor:
Bo-Hao Tang, Bu-Fan Yao, Wei Zhang, Xin-Fang Zhang, Shu-Meng Fu, Guo-Xiang Hao, Yue Zhou, De-Qing Sun, Gang Liu, John van den Anker, Yue-E Wu, Yi Zheng, Wei Zhao
Publikováno v:
EBioMedicine, Vol 105, Iss , Pp 105221- (2024)
Summary: Background: Accurate prediction of the optimal dose for β-lactam antibiotics in neonatal sepsis is challenging. We aimed to evaluate whether a reliable clinical decision support system (CDSS) based on machine learning (ML) can assist clinic
Externí odkaz:
https://doaj.org/article/581d71d13a7a42f8b96322701cce014a
Autor:
Xin Wang, Wei Zhao, John van den Anker, Guo-Xiang Hao, Yue-E Wu, Li-Yuan Zheng, Wei-Ping Gu, Na Liang, Li-Li Gao, Wen-Wen Guo, Rui-Rui Li
Publikováno v:
BMJ Paediatrics Open, Vol 7, Iss 1 (2023)
Background Antibacterial therapy plays a crucial role in neonatal infections. The efficacy of antibacterial agents is closely related to the actual dose given to neonates. So we evaluated factors potentially affecting the actual dose of intravenous a
Externí odkaz:
https://doaj.org/article/1ac66e0044c74fa6800a006f48724b0e
Autor:
Hao Zhang, Wei Zhao, Qiang Li, Zhi-Min Yang, Ying Geng, Yan-Zhe Sun, Yong-Lin Jiang, Li-Qing Wang, Yue-E Wu
Publikováno v:
BMJ Paediatrics Open, Vol 7, Iss 1 (2023)
The regulatory guidelines for the research and development of paediatric drugs are still evolving in China. The formulation of the guidelines started from learning and borrowing existing experience, and gradually changed to the exploration and improv
Externí odkaz:
https://doaj.org/article/639dc42ec9db48d4968aafac3c59c91f
Autor:
Zhen-Hai Shang, Yue-E Wu, Dong-Mei Lv, Wei Zhang, Wen-Qiang Liu, John van den Anker, Yan Xu, Wei Zhao
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Objective: The perspective of real-world study is especially relevant to newborns, enabling dosage regimen optimization and regulatory approval of medications for use in newborns. The aim of the present study was to conduct a pharmacokinetic analysis
Externí odkaz:
https://doaj.org/article/0c15fb00c8194fcca8f024624ace1810
Autor:
Yue-E Wu, Chen Kou, Xue Li, Bo-Hao Tang, Bu-Fan Yao, Guo-Xiang Hao, Yi Zheng, John van den Anker, Dian-Ping You, A-Dong Shen, Wei Zhao
Publikováno v:
Children, Vol 9, Iss 12, p 1998 (2022)
The pharmacokinetic (PK) studies of meropenem in Chinese newborns with late-onset sepsis (LOS) are still lacking. Causative pathogens of LOS and their susceptibility patterns in China differ from the data abroad. We, therefore, conducted a developmen
Externí odkaz:
https://doaj.org/article/1c7955a3f31e4374ad5e99cc2367a57a
Publikováno v:
Expert Review of Clinical Pharmacology. :1-13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33585bf38094a7a04a1233c8509006d3
https://doi.org/10.1080/17512433.2023.2181161
https://doi.org/10.1080/17512433.2023.2181161
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Carbapenem-resistant enterobacteriaceae (CRE) bloodstream infections have been rapidly spreading worldwide with a high mortality and pose a challenge to therapeutic decision-making, especially in premature neonates because insufficient empirical anti
Externí odkaz:
https://doaj.org/article/ef7f78d5444146fc8441e610facf6d93
Autor:
Yang Zhao, Bu-Fan Yao, Chen Kou, Hai-Yan Xu, Bo-Hao Tang, Yue-E Wu, Guo-Xiang Hao, Xin-Ping Zhang, Wei Zhao
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
ObjectiveCefepime is used to treat severe infections in neonates. Pharmacokinetic data have only been evaluated among preterm neonates and population pharmacokinetic model lacked external validation. Hence, our aim is to obtain the population pharmac
Externí odkaz:
https://doaj.org/article/e17dee18e7744d4bb8bb77e17cb088fc
Autor:
Chen Kou, Di‐Fei Li, Bo‐Hao Tang, Lei Dong, Bu‐Fan Yao, John van den Anker, Dian‐Ping You, Yue‐E Wu, Wei Zhao
Publikováno v:
British Journal of Clinical Pharmacology. 88:4950-4955
Early-onset sepsis (EOS) is one of the most significant causes of morbidity and mortality in neonates. Currently, amoxicillin is empirically used to treat neonates with EOS. However, data on its effectiveness in neonates with EOS are still limited. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2f110e4cb88f42203f718a8d85ba8bd
https://doi.org/10.1111/bcp.15521
https://doi.org/10.1111/bcp.15521