Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Yue-E Wu"'
Autor:
Bo-Hao Tang, Bu-Fan Yao, Wei Zhang, Xin-Fang Zhang, Shu-Meng Fu, Guo-Xiang Hao, Yue Zhou, De-Qing Sun, Gang Liu, John van den Anker, Yue-E Wu, Yi Zheng, Wei Zhao
Publikováno v:
EBioMedicine, Vol 105, Iss , Pp 105221- (2024)
Summary: Background: Accurate prediction of the optimal dose for β-lactam antibiotics in neonatal sepsis is challenging. We aimed to evaluate whether a reliable clinical decision support system (CDSS) based on machine learning (ML) can assist clinic
Externí odkaz:
https://doaj.org/article/581d71d13a7a42f8b96322701cce014a
Autor:
Xin Wang, Wei Zhao, John van den Anker, Guo-Xiang Hao, Yue-E Wu, Li-Yuan Zheng, Wei-Ping Gu, Na Liang, Li-Li Gao, Wen-Wen Guo, Rui-Rui Li
Publikováno v:
BMJ Paediatrics Open, Vol 7, Iss 1 (2023)
Background Antibacterial therapy plays a crucial role in neonatal infections. The efficacy of antibacterial agents is closely related to the actual dose given to neonates. So we evaluated factors potentially affecting the actual dose of intravenous a
Externí odkaz:
https://doaj.org/article/1ac66e0044c74fa6800a006f48724b0e
Autor:
Hao Zhang, Wei Zhao, Qiang Li, Zhi-Min Yang, Ying Geng, Yan-Zhe Sun, Yong-Lin Jiang, Li-Qing Wang, Yue-E Wu
Publikováno v:
BMJ Paediatrics Open, Vol 7, Iss 1 (2023)
The regulatory guidelines for the research and development of paediatric drugs are still evolving in China. The formulation of the guidelines started from learning and borrowing existing experience, and gradually changed to the exploration and improv
Externí odkaz:
https://doaj.org/article/639dc42ec9db48d4968aafac3c59c91f
Autor:
Shu-Ping Liu, Jing Xiao, Ya-Li Liu, Yue-E Wu, Hui Qi, Zhuang-Zhuang Wang, A-Dong Shen, Gang Liu, Wei Zhao
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Objective: The decision of vancomycin dosage for central nervous system (CNS) infections is still a challenge because its bactericidal nature in cerebrospinal fluid (CSF) has not been confirmed by human studies. This study systematically reviewed the
Externí odkaz:
https://doaj.org/article/b503ddd62fa946b29080eff67de9aec0
Autor:
Xue Tian, Lei Dong, Ting-Ting Jiang, Bo-Hao Tang, Ze-Ming Wang, Yue-E Wu, Dian-Ping You, Jing Bi, Su-Yun Qian, Hui Qi, A-Dong Shen
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Pneumonia, caused by infection or other factors, seriously endangers the health of children. Meropenem is an effective broad-spectrum antibiotic using in the treatment of infectious diseases. In the therapy of pneumonia, meropenem is most
Externí odkaz:
https://doaj.org/article/e05962eaeded49eb97e491d6df70cb16
Autor:
Zhen-Hai Shang, Yue-E Wu, Dong-Mei Lv, Wei Zhang, Wen-Qiang Liu, John van den Anker, Yan Xu, Wei Zhao
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Objective: The perspective of real-world study is especially relevant to newborns, enabling dosage regimen optimization and regulatory approval of medications for use in newborns. The aim of the present study was to conduct a pharmacokinetic analysis
Externí odkaz:
https://doaj.org/article/0c15fb00c8194fcca8f024624ace1810
Autor:
Yue-E Wu, Chen Kou, Xue Li, Bo-Hao Tang, Bu-Fan Yao, Guo-Xiang Hao, Yi Zheng, John van den Anker, Dian-Ping You, A-Dong Shen, Wei Zhao
Publikováno v:
Children, Vol 9, Iss 12, p 1998 (2022)
The pharmacokinetic (PK) studies of meropenem in Chinese newborns with late-onset sepsis (LOS) are still lacking. Causative pathogens of LOS and their susceptibility patterns in China differ from the data abroad. We, therefore, conducted a developmen
Externí odkaz:
https://doaj.org/article/1c7955a3f31e4374ad5e99cc2367a57a
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/b51589ac30c84caead8ca233a7090eaa
Autor:
Qian Li, Yue-E Wu, Kai Wang, Hai-Yan Shi, Yue Zhou, Yi Zheng, Guo-Xiang Hao, Yi-Lei Yang, Le-Qun Su, Wen-Qi Wang, Xin-Mei Yang, Wei Zhao
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Objective: The elucidation of CYP2D6 developmental pharmacogenetics in children has improved, however, these findings have been largely limited to studies of Caucasian children. Given the clear differences in CYP2D6 pharmacogenetic profiles in people
Externí odkaz:
https://doaj.org/article/43a25d8b9d0446b79191265f7e33ceae
Autor:
Hui Qi, Yue-E Wu, Ya-Li Liu, Chen Kou, Ze-Ming Wang, Xiao-Xia Peng, Liang Chen, Hong Cui, Ya-Juan Wang, Jie-Qiong Li, Wei Zhao, A-Dong Shen
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Early-onset neonatal sepsis (EONS), a bacterial infection that occurs within 72 h after birth, is associated with high likelihood of neonatal mortality. Latamoxef, a semi-synthetic oxacephem antibiotic developed in 1980s, has been brought back into e
Externí odkaz:
https://doaj.org/article/2cd0f25c1204480ab03d38522c5f7c83