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MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer.

Autor: Zheng SM; General Surgery Department, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, P.R. China.; Translational Research Institute, Henan Provincial and Zhengzhou City Key Laboratory of Non-coding RNA and Cancer Metabolism, Henan International Join Laboratory of Non-coding RNA and Metabolism in Cancer, Henan Provincial People's Hospital, Academy of Medical Sciences, Zhengzhou University, Henan, P.R. China., Feng YC; School of Medicine and Public Health, The University of Newcastle, New South Wales, Australia., Zhu Q; General Surgery Department, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, P.R. China., Li RQ; General Surgery Department, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, P.R. China., Yan QQ; Translational Research Institute, Henan Provincial and Zhengzhou City Key Laboratory of Non-coding RNA and Cancer Metabolism, Henan International Join Laboratory of Non-coding RNA and Metabolism in Cancer, Henan Provincial People's Hospital, Academy of Medical Sciences, Zhengzhou University, Henan, P.R. China., Teng L; Translational Research Institute, Henan Provincial and Zhengzhou City Key Laboratory of Non-coding RNA and Cancer Metabolism, Henan International Join Laboratory of Non-coding RNA and Metabolism in Cancer, Henan Provincial People's Hospital, Academy of Medical Sciences, Zhengzhou University, Henan, P.R. China., Yue YM; Translational Research Institute, Henan Provincial and Zhengzhou City Key Laboratory of Non-coding RNA and Cancer Metabolism, Henan International Join Laboratory of Non-coding RNA and Metabolism in Cancer, Henan Provincial People's Hospital, Academy of Medical Sciences, Zhengzhou University, Henan, P.R. China., Han MM; Translational Research Institute, Henan Provincial and Zhengzhou City Key Laboratory of Non-coding RNA and Cancer Metabolism, Henan International Join Laboratory of Non-coding RNA and Metabolism in Cancer, Henan Provincial People's Hospital, Academy of Medical Sciences, Zhengzhou University, Henan, P.R. China., Ye K; Translational Research Institute, Henan Provincial and Zhengzhou City Key Laboratory of Non-coding RNA and Cancer Metabolism, Henan International Join Laboratory of Non-coding RNA and Metabolism in Cancer, Henan Provincial People's Hospital, Academy of Medical Sciences, Zhengzhou University, Henan, P.R. China., Zhang SN; Translational Research Institute, Henan Provincial and Zhengzhou City Key Laboratory of Non-coding RNA and Cancer Metabolism, Henan International Join Laboratory of Non-coding RNA and Metabolism in Cancer, Henan Provincial People's Hospital, Academy of Medical Sciences, Zhengzhou University, Henan, P.R. China., Qi TF; Translational Research Institute, Henan Provincial and Zhengzhou City Key Laboratory of Non-coding RNA and Cancer Metabolism, Henan International Join Laboratory of Non-coding RNA and Metabolism in Cancer, Henan Provincial People's Hospital, Academy of Medical Sciences, Zhengzhou University, Henan, P.R. China., Tang CX; Translational Research Institute, Henan Provincial and Zhengzhou City Key Laboratory of Non-coding RNA and Cancer Metabolism, Henan International Join Laboratory of Non-coding RNA and Metabolism in Cancer, Henan Provincial People's Hospital, Academy of Medical Sciences, Zhengzhou University, Henan, P.R. China., Zhao XH; School of Biomedical Sciences and Pharmacy, The University of Newcastle, New South Wales, Australia., Zhang YY; School of Biomedical Sciences and Pharmacy, The University of Newcastle, New South Wales, Australia., Xu L; School of Biomedical Sciences and Pharmacy, The University of Newcastle, New South Wales, Australia., Xu R; School of Biomedical Sciences and Pharmacy, The University of Newcastle, New South Wales, Australia., Xing J; General Surgery Department, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, P.R. China., Baker M; School of Biomedical Sciences and Pharmacy, The University of Newcastle, New South Wales, Australia., Liu T; Children's Cancer Institute Australia for Medical Research, University of New South Wales, New South Wales, Australia., Thorne RF; School of Biomedical Sciences and Pharmacy, The University of Newcastle, New South Wales, Australia., Jin L; School of Medicine and Public Health, The University of Newcastle, New South Wales, Australia., Preiss T; Shine-Dalgarno Centre for RNA Innovation, John Curtin School of Medical Research, Australian National University, Canberra, Australia.; Victor Chang Cardiac Research Institute, Sydney, New South Wales, Australia., Zhang XD; Translational Research Institute, Henan Provincial and Zhengzhou City Key Laboratory of Non-coding RNA and Cancer Metabolism, Henan International Join Laboratory of Non-coding RNA and Metabolism in Cancer, Henan Provincial People's Hospital, Academy of Medical Sciences, Zhengzhou University, Henan, P.R. China.; School of Biomedical Sciences and Pharmacy, The University of Newcastle, New South Wales, Australia., Cang S; Department of Oncology, Henan Provincial International Coalition Laboratory of Oncology Precision Treatment, Henan Provincial Academician Workstation of Non-coding RNA Translational Research, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Henan, P.R. China., Gao JN; General Surgery Department, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, P.R. China.

Publikováno v: Cancer research [Cancer Res] 2024 May 02; Vol. 84 (9), pp. 1460-1474.

The N-Myc-responsive lncRNA MILIP promotes DNA double-strand break repair through non-homologous end joining.

Autor: Wang PL; Translational Research Institute, Henan Provincial and Zhengzhou City Key laboratory of Non-coding RNA and Cancer Metabolism, Henan International Join Laboratory of Non-coding RNA and Metabolism in Cancer, Henan Provincial People's Hospital, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450053, China., Teng L; Translational Research Institute, Henan Provincial and Zhengzhou City Key laboratory of Non-coding RNA and Cancer Metabolism, Henan International Join Laboratory of Non-coding RNA and Metabolism in Cancer, Henan Provincial People's Hospital, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450053, China., Feng YC; School of Medicine and Public Health, The University of Newcastle, Newcastle, NSW 2308, Australia., Yue YM; Translational Research Institute, Henan Provincial and Zhengzhou City Key laboratory of Non-coding RNA and Cancer Metabolism, Henan International Join Laboratory of Non-coding RNA and Metabolism in Cancer, Henan Provincial People's Hospital, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450053, China., Han MM; Translational Research Institute, Henan Provincial and Zhengzhou City Key laboratory of Non-coding RNA and Cancer Metabolism, Henan International Join Laboratory of Non-coding RNA and Metabolism in Cancer, Henan Provincial People's Hospital, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450053, China., Yan Q; Translational Research Institute, Henan Provincial and Zhengzhou City Key laboratory of Non-coding RNA and Cancer Metabolism, Henan International Join Laboratory of Non-coding RNA and Metabolism in Cancer, Henan Provincial People's Hospital, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450053, China., Ye K; Translational Research Institute, Henan Provincial and Zhengzhou City Key laboratory of Non-coding RNA and Cancer Metabolism, Henan International Join Laboratory of Non-coding RNA and Metabolism in Cancer, Henan Provincial People's Hospital, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450053, China., Tang CX; Translational Research Institute, Henan Provincial and Zhengzhou City Key laboratory of Non-coding RNA and Cancer Metabolism, Henan International Join Laboratory of Non-coding RNA and Metabolism in Cancer, Henan Provincial People's Hospital, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450053, China., Zhang SN; Translational Research Institute, Henan Provincial and Zhengzhou City Key laboratory of Non-coding RNA and Cancer Metabolism, Henan International Join Laboratory of Non-coding RNA and Metabolism in Cancer, Henan Provincial People's Hospital, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450053, China., Fei Qi T; Translational Research Institute, Henan Provincial and Zhengzhou City Key laboratory of Non-coding RNA and Cancer Metabolism, Henan International Join Laboratory of Non-coding RNA and Metabolism in Cancer, Henan Provincial People's Hospital, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450053, China., Zhao XH; School of Biomedical Sciences and Pharmacy, The University of Newcastle, Newcastle, NSW 2308, Australia., La T; School of Biomedical Sciences and Pharmacy, The University of Newcastle, Newcastle, NSW 2308, Australia., Zhang YY; School of Biomedical Sciences and Pharmacy, The University of Newcastle, Newcastle, NSW 2308, Australia., Li JM; Translational Research Institute, Henan Provincial and Zhengzhou City Key laboratory of Non-coding RNA and Cancer Metabolism, Henan International Join Laboratory of Non-coding RNA and Metabolism in Cancer, Henan Provincial People's Hospital, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450053, China., Hu B; Department of Oncology and Oncology Radiotherapy, Henan Provincial People's Hospital, Henan 450003, Zhengzhou, China., Xu D; Department of Oncology and Oncology Radiotherapy, Henan Provincial People's Hospital, Henan 450003, Zhengzhou, China., Cang S; Department of Oncology and Oncology Radiotherapy, Henan Provincial People's Hospital, Henan 450003, Zhengzhou, China., Wang L; Translational Research Institute, Henan Provincial and Zhengzhou City Key laboratory of Non-coding RNA and Cancer Metabolism, Henan International Join Laboratory of Non-coding RNA and Metabolism in Cancer, Henan Provincial People's Hospital, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450053, China.; School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450003, China., Jin L; Translational Research Institute, Henan Provincial and Zhengzhou City Key laboratory of Non-coding RNA and Cancer Metabolism, Henan International Join Laboratory of Non-coding RNA and Metabolism in Cancer, Henan Provincial People's Hospital, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450053, China.; School of Medicine and Public Health, The University of Newcastle, Newcastle, NSW 2308, Australia., Thorne RF; Translational Research Institute, Henan Provincial and Zhengzhou City Key laboratory of Non-coding RNA and Cancer Metabolism, Henan International Join Laboratory of Non-coding RNA and Metabolism in Cancer, Henan Provincial People's Hospital, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450053, China.; School of Biomedical Sciences and Pharmacy, The University of Newcastle, Newcastle, NSW 2308, Australia., Zhang Y; Henan Key Laboratory of Stem Cell Differentiation and Modification, Henan Provincial People's Hospital, Henan University, Zhengzhou, Henan 450003, China., Liu T; Translational Research Institute, Henan Provincial and Zhengzhou City Key laboratory of Non-coding RNA and Cancer Metabolism, Henan International Join Laboratory of Non-coding RNA and Metabolism in Cancer, Henan Provincial People's Hospital, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450053, China.; Children's Cancer Institute Australia for Medical Research, University of New South Wales, Sydney, NSW 2750, Australia., Zhang XD; Translational Research Institute, Henan Provincial and Zhengzhou City Key laboratory of Non-coding RNA and Cancer Metabolism, Henan International Join Laboratory of Non-coding RNA and Metabolism in Cancer, Henan Provincial People's Hospital, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450053, China.; School of Biomedical Sciences and Pharmacy, The University of Newcastle, Newcastle, NSW 2308, Australia.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Dec 06; Vol. 119 (49), pp. e2208904119. Date of Electronic Publication: 2022 Nov 29.

The pan-cancer lncRNA PLANE regulates an alternative splicing program to promote cancer pathogenesis.

Autor: Teng L; Translational Research Institute, Henan Provincial People's Hospital and People's Hospital of Zhengzhou University, Academy of Medical Science, Zhengzhou University, Henan, China., Feng YC; School of Medicine and Public Health, The University of Newcastle, Callaghan, NSW, Australia., Guo ST; Department of Molecular Biology, Shanxi Cancer Hospital and Institute, Shanxi, China., Wang PL; Translational Research Institute, Henan Provincial People's Hospital and People's Hospital of Zhengzhou University, Academy of Medical Science, Zhengzhou University, Henan, China., Qi TF; Translational Research Institute, Henan Provincial People's Hospital and People's Hospital of Zhengzhou University, Academy of Medical Science, Zhengzhou University, Henan, China., Yue YM; Translational Research Institute, Henan Provincial People's Hospital and People's Hospital of Zhengzhou University, Academy of Medical Science, Zhengzhou University, Henan, China., Wang SX; Translational Research Institute, Henan Provincial People's Hospital and People's Hospital of Zhengzhou University, Academy of Medical Science, Zhengzhou University, Henan, China., Zhang SN; Translational Research Institute, Henan Provincial People's Hospital and People's Hospital of Zhengzhou University, Academy of Medical Science, Zhengzhou University, Henan, China., Tang CX; Translational Research Institute, Henan Provincial People's Hospital and People's Hospital of Zhengzhou University, Academy of Medical Science, Zhengzhou University, Henan, China., La T; School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW, Australia., Zhang YY; School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW, Australia., Zhao XH; School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW, Australia., Gao JN; Department of Breast Surgery, Shanxi Bethune Hospital, Shanxi, China., Wei LY; Department of Breast Surgery, Shanxi Bethune Hospital, Shanxi, China., Zhang D; Orthopaedics Department, John Hunter Hospital, Hunter New England Health, New Lambton, NSW, Australia., Wang JY; Children's Cancer Institute Australia for Medical Research, University of New South Wales, Sydney, NSW, Australia., Shi Y; Department of Pathology, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Henan, China., Liu XY; Translational Research Institute, Henan Provincial People's Hospital and People's Hospital of Zhengzhou University, Academy of Medical Science, Zhengzhou University, Henan, China., Li JM; Translational Research Institute, Henan Provincial People's Hospital and People's Hospital of Zhengzhou University, Academy of Medical Science, Zhengzhou University, Henan, China., Cao H; Department of Nephrology, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Henan, China., Liu T; Translational Research Institute, Henan Provincial People's Hospital and People's Hospital of Zhengzhou University, Academy of Medical Science, Zhengzhou University, Henan, China.; Children's Cancer Institute Australia for Medical Research, University of New South Wales, Sydney, NSW, Australia., Thorne RF; Translational Research Institute, Henan Provincial People's Hospital and People's Hospital of Zhengzhou University, Academy of Medical Science, Zhengzhou University, Henan, China.; School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW, Australia., Jin L; Translational Research Institute, Henan Provincial People's Hospital and People's Hospital of Zhengzhou University, Academy of Medical Science, Zhengzhou University, Henan, China. Lei.Jin@newcastle.edu.au.; School of Medicine and Public Health, The University of Newcastle, Callaghan, NSW, Australia. Lei.Jin@newcastle.edu.au., Shao FM; Department of Nephrology, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Henan, China. fengminshao@126.com., Zhang XD; Translational Research Institute, Henan Provincial People's Hospital and People's Hospital of Zhengzhou University, Academy of Medical Science, Zhengzhou University, Henan, China. Xu.Zhang@newcastle.edu.au.; School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW, Australia. Xu.Zhang@newcastle.edu.au.

Publikováno v: Nature communications [Nat Commun] 2021 Jun 18; Vol. 12 (1), pp. 3734. Date of Electronic Publication: 2021 Jun 18.