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Supplementary Figure 3 from Mitogen-Activated Protein Kinase Phosphatase-1 Is a Mediator of Breast Cancer Chemoresistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b4e43b1e475a6504a7410426d654eb3
https://doi.org/10.1158/0008-5472.22368294.v1
https://doi.org/10.1158/0008-5472.22368294.v1
Supplementary Figure 1 from Mitogen-Activated Protein Kinase Phosphatase-1 Is a Mediator of Breast Cancer Chemoresistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::925373acaf33839cda22be645867677f
https://doi.org/10.1158/0008-5472.22368300.v1
https://doi.org/10.1158/0008-5472.22368300.v1
The mitogen-activated protein kinase (MAPK) phosphatase (MKP)-1 is overexpressed in a large proportion of breast cancers, and in some systems interferes with chemotherapy-mediated proapoptotic signaling through c-Jun-NH2-terminal kinase (JNK). We the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ac01111ba6668597f4df78dd773b243
https://doi.org/10.1158/0008-5472.c.6495897
https://doi.org/10.1158/0008-5472.c.6495897
Supplementary Figure 4 from Mitogen-Activated Protein Kinase Phosphatase-1 Is a Mediator of Breast Cancer Chemoresistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::470a438634eddc5019e1cafa08391f5c
https://doi.org/10.1158/0008-5472.22368291.v1
https://doi.org/10.1158/0008-5472.22368291.v1
Supplementary Figure 2 from Mitogen-Activated Protein Kinase Phosphatase-1 Is a Mediator of Breast Cancer Chemoresistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e4bfdcc4e47de189e86bc38f7828cc
https://doi.org/10.1158/0008-5472.22368297.v1
https://doi.org/10.1158/0008-5472.22368297.v1
Publikováno v:
Cancer Research. 67:4459-4466
The mitogen-activated protein kinase (MAPK) phosphatase (MKP)-1 is overexpressed in a large proportion of breast cancers, and in some systems interferes with chemotherapy-mediated proapoptotic signaling through c-Jun-NH2-terminal kinase (JNK). We the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc54e46f58d59731a5f0ca51d5afc95
https://doi.org/10.1158/0008-5472.can-06-2644
https://doi.org/10.1158/0008-5472.can-06-2644
Autor:
George W. Small, S Somasundaram, Robert Z. Orlowski, Yue Y. Shi, Dominic T. Moore, Natalie A. Edmund
Publikováno v:
Molecular Pharmacology. 66:1478-1490
Inhibitors of the proteasome, a multicatalytic proteinase complex responsible for intracellular proteolysis, activate programmed cell death in part through the c-Jun-N-terminal kinase (JNK). Proteasome inhibitors also induce mitogen-activated protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e33e88373c383e9de15aa13c6a1caea
https://doi.org/10.1124/mol.104.003400
https://doi.org/10.1124/mol.104.003400
Publikováno v:
Breast cancer research and treatment. 100(1)
Proteasome inhibitors represent a novel class of anti-tumor agents that have clinical efficacy against hematologic malignancies, but single-agent activity against solid tumors such as breast cancer has been disappointing, perhaps due to activation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b171cf8a487ba6c7e39fb23def141b0
https://pubmed.ncbi.nlm.nih.gov/16807678
https://pubmed.ncbi.nlm.nih.gov/16807678
Autor:
Sivagurunathan, Somasundaram, Natalie A, Edmund, Dominic T, Moore, George W, Small, Yue Y, Shi, Robert Z, Orlowski
Publikováno v:
Cancer research. 62(13)
Curcumin, the major component of the spice turmeric, is used as a coloring and flavoring additive in many foods and has attracted interest because of its anti-inflammatory and chemopreventive activities. However, this agent also inhibits the generati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::abefc56c8893d4ef176ce6996269c81b
https://pubmed.ncbi.nlm.nih.gov/12941849
https://pubmed.ncbi.nlm.nih.gov/12941849
The proteasome is emerging as a target for cancer therapy because small molecule inhibitors of its catalytic activity induce apoptosis in both in vitro and in vivo models of human malignancies and are proving to have efficacy in early clinical trials
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::439c9fa32333009d1c50fc2d98eff3a2