Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Yue Sheng Long"'
Autor:
Luping Yin, Rui Zheng, Wei Ke, Quansheng He, Yi Zhang, Junlong Li, Bo Wang, Zhen Mi, Yue-sheng Long, Malte J. Rasch, Tianfu Li, Guoming Luan, Yousheng Shu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
While autapses are synapses made by a neuron onto itself, its functional significance in pyramidal cells are not clear. Here, the authors show that in the mammalian neocortex, autapses of pyramidal cells can enhance burst firing and coincidence detec
Externí odkaz:
https://doaj.org/article/387d2ac97fcc4d5db68d5938d05e9905
Autor:
Yue-Sheng Long, Hui-Ling Tang, Mei-Mei Gao, Si-Yu Chen, Fei Hu, Hua-Juan Yan, Ping Lu, Hao-Ying Huang, Wen-Cai Feng, Na He
Publikováno v:
Brain Research Bulletin. 170:81-89
Aberrant expression or dysfunction of a number of genes in the brain contributes to epilepsy, a common neurological disorder characterized by recurrent seizures. Local overexpression of arachidonate lipoxygenase 3 (ALOXE3), a key enzyme for arachidon
Publikováno v:
Journal of proteomics. 269
Loss of fragile X retardation protein (FMRP) leads to fragile X syndrome (FXS), a common cause of inherited intellectual disability. Protein lysine acetylation (K-ac), a reversible post-translational modification of proteins, is associated with the r
Autor:
Tao Su, Mei-Mei Gao, Si-Yu Chen, Xiang-Da Zeng, Hui-Ling Tang, Weiwen Sun, Ping Lu, Yue-Sheng Long, Huan Zhang
Publikováno v:
Cellular and Molecular Neurobiology. 42:777-790
Arachidonic acid (AA), a polyunsaturated fatty acid, is involved in the modulation of neuronal excitability in the brain. Arachidonate lipoxygenase 3 (ALOXE3), a critical enzyme in the AA metabolic pathway, catalyzes the derivate of AA into hepoxilin
Autor:
Yue-Sheng Long, Xiang-Da Zeng, Mei-Mei Gao, Ping Lu, Si-Yu Chen, Huan Zhang, Hui-Ling Tang, Hang Shi, Wei Jiang, Hua-Juan Yan
Publikováno v:
Cellular and Molecular Neurobiology. 41:1257-1269
Valproate (VPA), a widely-used antiepileptic drug, is a selective inhibitor of histone deacetylase (HDAC) that play important roles in epigenetic regulation. The patient with different diseases receiving this drug tend to exhibit weight gain and abno
Autor:
Yong-Hong Yi, Yue-Sheng Long, Tao Su, Bin Li, Na He, Yang Zeng, Wei-Ping Liao, Bin Tang, Liang-Di Gao, Xiao-Rong Liu
Publikováno v:
Briefings in Bioinformatics. 21:1776-1786
Genes are unique in functional role and differ in their sensitivities to genetic defects, but with difficulties in pathogenicity prediction. This study attempted to improve the performance of existing in silico algorithms and find a common solution b
Autor:
Ping Lu, Cui Yang, Yue-Sheng Long, Hua-Juan Yan, Mei-Mei Gao, Wen-Cai Feng, Yue-Ying Wu, Fei Hu, Wei-Wen Sun
Publikováno v:
Life sciences. 272
High fat consumption leads to reactive oxygen species (ROS) which is associated with age-progressive neurological disorders. Cu/Zn superoxide dismutase (SOD1) is a critical enzyme against ROS. However, the relationship between SOD1 and the high-fat-i
Autor:
Hui-Ling, Tang, Si-Yu, Chen, Huan, Zhang, Ping, Lu, Wei-Wen, Sun, Mei-Mei, Gao, Xiang-Da, Zeng, Tao, Su, Yue-Sheng, Long
Publikováno v:
Cellular and molecular neurobiology. 42(3)
Arachidonic acid (AA), a polyunsaturated fatty acid, is involved in the modulation of neuronal excitability in the brain. Arachidonate lipoxygenase 3 (ALOXE3), a critical enzyme in the AA metabolic pathway, catalyzes the derivate of AA into hepoxilin
Autor:
Tianfu Li, Junlong Li, Wei Ke, Malte J. Rasch, Yue-Sheng Long, Rui Zheng, Quansheng He, Yousheng Shu, Luping Yin, Zhen Mi, Yi Zhang, Guoming Luan, B. D. Wang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Nature Communications
Nature Communications
Autapses are synaptic contacts of a neuron’s axon onto its own dendrite and soma. In the neocortex, self-inhibiting autapses in GABAergic interneurons are abundant in number and play critical roles in regulating spike precision and network activity