Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Yue C Lu"'
Autor:
Igor Odintsov, Ryan C. Cheng, Allan J. Lui, Tom Zhang, Yue C. Lu, Renate I. Kurth, Morana Vojnic, Inna Khodos, Qing Chang, Kevin Chen, Claudio Giuliano, Annalisa Bonifacio, Isao Miyazaki, Elisa de Stanchina, Emanuela Lovati, Marc Ladanyi, Romel Somwar
Publikováno v:
Cancer Research. 83:4007-4007
Background: Vepafestinib (TAS0953/HM06, Vepa) is a 2nd generation RET-selective inhibitor that effectively penetrates the brain, and inhibits the wildtype RET kinase domain (KD) and RET KD mutants (G810, V804, Y806, L730) (presented at AACR-NCI-EROTC
Autor:
Dana L. Casey, Luc G. T. Morris, Nadeem Riaz, Timothy A. Chan, Howard I. Scher, Robert M. Samstein, Lior Z. Braunstein, Xinmao Song, Kenneth L. Pitter, Margaret Hannum, Diana Mandelker, Isabella Pecorari, Paul B. Romesser, Christopher A. Barker, Jeremy Setton, Atif J. Khan, Joachim Yahalom, Nancy Y. Lee, Isaac X Pei, Jennifer Ma, Kaled M. Alektiar, Yue C Lu, Christopher H. Crane, S.N. Powell, Jorge S. Reis-Filho, Biko McMillan, Michael J. Zelefsky, Jonine L. Bernstein, Zhigang Zhang, Andreas Rimner, Britta Weigelt
Publikováno v:
J Natl Cancer Inst
Background Radiation therapy is one of the most commonly used cancer therapeutics but genetic determinants of clinical benefit are poorly characterized. Pathogenic germline variants in ATM are known to cause ataxia-telangiectasia, a rare hereditary s
Autor:
Hsiao-Ming Lu, Annie W. Chan, Norbert J. Liebsch, Hugh D. Curtin, Nina N. Sanford, Jackson Lau, Amy F. Juliano, Miranda B. Lam, Judith Adams, Saveli Goldberg, Yue C. Lu
Publikováno v:
International journal of radiation oncology, biology, physics. 103(3)
Purpose Radiation-related toxicity in nasopharyngeal carcinoma (NPC) is common. There are no well-established guidelines for clinical target volume (CTV) delineation with long-term follow-up. Current consensus continues to rely heavily on bony landma
Autor:
Yue C. Lu, Richard Sando, Nan-Sheng Li, Gabriel S. Salzman, Thomas C. Südhof, Demet Araç, Olha V. Nazarko
Publikováno v:
Structure. 24(2)
SummaryFibronectin leucine-rich repeat transmembrane proteins (FLRTs) are cell-adhesion molecules with emerging functions in cortical development and synapse formation. Their extracellular regions interact with latrophilins (LPHNs) to mediate synapse
Autor:
Olha V. Nazarko, Amanuel Kibrom, Jingxian Li, Georgios Skiniotis, Thomas C. Südhof, Katherine Leon, Yue C. Lu, Xian Jiang, Jie Wang, Richard Sando, Moran Shalev-Benami, Demet Araç, Christopher D. Katanski
Publikováno v:
Cell. 173:735-748.e15
Teneurins (TENs) are cell-surface adhesion proteins with critical roles in tissue development and axon guidance. Here we report the 3.1-Å electron cryo-microscopy structure of the human TEN2 extracellular region (ECR), revealing a striking similarit