Zobrazeno 1 - 10 of 46 pro vyhledávání: '"Yue‐Ming Yu"'
1
Self-assembly of antifungal agent 5-fluorocytosine and nutrient trans-p-coumaric acid furnishes a cocrystal with the potential to reduce toxicity and side effects for the drug: a case study combining theory with experiment
Autor: Fan-Zhi Bu, Yue-Ming Yu, Yu Yu, Cui-Wei Yan, Zhi-Yong Wu, Yan-Tuan Li
Publikováno v: New Journal of Chemistry. 47:1328-1341
Cocrystallization of 5-fluorocytosine (FLCY) and trans-p-coumaric acid was first reported. Systematic studies combining theory with experiment revealed that both solubility and dissolution rate of FLCY can be down-regulated via cocrystallization.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d6c2a52f823d318835003fdef02c799a
https://doi.org/10.1039/d2nj03622c
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2
Salification-driven strategy toward the hydrophobic molecular salt of the antifungal drug 5-fluorocytosine and protocatechuic acid with triple-helix structure offers an innovative insight for conquering adverse drug reactions
Autor: Fan-Zhi Bu, Yue-Ming Yu, Lin-Lin Zhang, Cui-Wei Yan, Zhi-Yong Wu, Yan-Tuan Li
Publikováno v: CrystEngComm. 25:1951-1964
The hydrophobic molecular salt of 5-fluorocytosine (FYT) with protocatechuic acid (PCA) was first reported, and its dissolution behaviors were systematically studied by combining theory with experiment.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fe0bfa6034005f00ebd025bebe624fb7
https://doi.org/10.1039/d2ce01523d
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3
Supramolecular self-assembly with p-coumaric acid offers the first cocrystal for perfecting the physicochemical peculiarity and enhancing the antifungal effect of drug bifonazole
Autor: Min Zhang, Min-Yu Wang, Yue-Ming Yu, Su-Su Meng, Cui-Wei Yan, Zhi-Yong Wu, Yan-Tuan Li
Publikováno v: CrystEngComm. 25:2789-2801
The first cocrystal of bifonazole is assembled, and the pharmaceutical properties are investigated theoretically and experimentally, revealing that the physicochemical properties and antifungal ability are enhanced simultaneously.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2803a712c91a7d41f1555b71ac5fdc12
https://doi.org/10.1039/d3ce00082f
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4
5-fluorouracil-caffeic acid cocrystal delivery agent with long-term and synergistic high-performance antitumor effects
Autor: Yue-Ming Yu, Fan-Zhi Bu, Yu Yu, Cui-Wei Yan, Zhi-Yong Wu, Yan-Tuan Li
Publikováno v: Nanomedicine. 17:2215-2229
Aim: To explore how to transform cocrystals of the anticancer drug 5-fluorouracil (FL) with caffeic acid (CF; FL-CF-2H2O) into a nanoformulation, a self-assembly strategy of cocrystal-loaded micelles is proposed. Methods: Nanomicelles were assembled
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f0321ab83c8a4b7ae62b7479a0c8702
https://doi.org/10.2217/nnm-2022-0208
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6
miR ‐219a‐5p inhibits the pyroptosis in knee osteoarthritis by inactivating the NLRP3 signaling via targeting FBXO3
Autor: Qiang Wang, Pei‐Yan Huang, Jun‐Guo Wu, Tie‐Qi Zhang, Ling‐Feng Li, Liang‐Da Huang, Yue‐Ming Yu, Ming‐hai Wang, Jun He
Publikováno v: Environmental Toxicology. 37:2673-2682
This work was to identify the function and mechanism of miR-219a-5p in regulating knee osteoarthritis (KOA).Rat fibroblast-like synoviocytes (FLSs) were isolated to construct KOA cell model by lipopolysaccharide and adenosine triphosphate treatment.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fc9778ee17c099f6db8ece6a7be7bd6
https://doi.org/10.1002/tox.23627
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7
Cocrystallization-driven self-assembly with vanillic acid offers a new opportunity for surmounting fast and excessive absorption issues of antifungal drug 5-fluorocytosine: a combined theoretical and experimental research
Autor: Fan-Zhi Bu, Yue-Ming Yu, Yu-Li Shen, Lu Liu, Cui-Wei Yan, Zhi-Yong Wu, Yan-Tuan Li
Publikováno v: CrystEngComm. 24:2777-2790
The cocrystal of 5-fluorocytosine (FCY) with vanillic acid (VAA) was assembled via a cocrystallization technique, giving a novel understanding for conquering the dose-limited hepatotoxicity caused by the rapid and almost complete absorption of FCY.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c8a61a4caa859c3cfff1d09b2818d426
https://doi.org/10.1039/d2ce00114d
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9
[Experience of Community-based Home Hospice Care Practice for 24 Patients in Beijing Puhuangyu Community]
Autor: Ming-Hui, Wang, Yue-Ming, Yu, Ru-Jin, Liu, Hong, Liu, Rui, Sha, Qian, Liu, Yan-Xin, Liu, Xiao-Hong, Ning
Publikováno v: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. 44(5)
Objective To investigate the feasibility of home hospice care based on the practical experience in Puhuangyu community of Beijing.Methods We selected the patients assessed by hospice care team and receiving home hospice care from Puhuangyu Community
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::600c4f6675c028b8086abfa8bbf4c84f
https://pubmed.ncbi.nlm.nih.gov/36325770
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10
[Community-based Home Hospice Care Model under the Guidance of Tertiary Hospitals]
Autor: Ru-Jin, Liu, Ming-Hui, Wang, Yue-Ming, Yu, Hong, Liu, Rui, Sha, Qian, Liu, Yan-Xin, Liu, Xiao-Hong, Ning
Publikováno v: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. 44(5)
Community-based home hospice care provided by community service centers and family physician teams aims to alleviate the suffering of terminally ill patients and help them to receive end-of-life care and pass away at home.The Puhuangyu Community Heal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4f5e3f94f4077366784fb3192a2141ba
https://pubmed.ncbi.nlm.nih.gov/36325768
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