Tackling APOE's structural challenges via in silico modeling in the era of neural networks: Can AlphaFold II help circumvent the problem of lacking full-length protein structure?

Autor: Mamchur AA; Centre for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, bld.10/1, Pogodinskaya Str., Moscow, 119121, Russia; The Faculty of Biology of Lomonosov Moscow State University, Leninskie Gory, 1, Moscow, 119991, Russia. Electronic address: amamchur@cspfmba.ru., Ivanov MV; Centre for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, bld.10/1, Pogodinskaya Str., Moscow, 119121, Russia., Matkava LR; Centre for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, bld.10/1, Pogodinskaya Str., Moscow, 119121, Russia., Yudin VS; Centre for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, bld.10/1, Pogodinskaya Str., Moscow, 119121, Russia., Keskinov AA; Centre for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, bld.10/1, Pogodinskaya Str., Moscow, 119121, Russia., Yudin SM; Centre for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, bld.10/1, Pogodinskaya Str., Moscow, 119121, Russia., Kashtanova DA; Centre for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, bld.10/1, Pogodinskaya Str., Moscow, 119121, Russia.

Publikováno v: Archives of biochemistry and biophysics [Arch Biochem Biophys] 2024 Nov; Vol. 761, pp. 110185. Date of Electronic Publication: 2024 Oct 22.

[A clinical case of reverse left ventricular remodeling in patient with pathogenic TTN mutation. Case report].

Autor: Nasonova SN; Chazov National Medical Research Center of Cardiology., Meshkov AN; Chazov National Medical Research Center of Cardiology.; National Research Center for Therapy and Preventive Medicine., Zhirov IV; Chazov National Medical Research Center of Cardiology., Osmolovskaya YF; Chazov National Medical Research Center of Cardiology., Shoshina AA; Chazov National Medical Research Center of Cardiology., Gagloev AV; Chazov National Medical Research Center of Cardiology., Dzhumaniiazova IH; Centre for Strategic Planning and Management of Biomedical Health Risks., Zelenova EA; Centre for Strategic Planning and Management of Biomedical Health Risks., Erema VV; Centre for Strategic Planning and Management of Biomedical Health Risks., Gusakova MS; Centre for Strategic Planning and Management of Biomedical Health Risks., Ivanov MV; Centre for Strategic Planning and Management of Biomedical Health Risks., Terekhov MV; Centre for Strategic Planning and Management of Biomedical Health Risks., Kashtanova DA; Centre for Strategic Planning and Management of Biomedical Health Risks., Nekrasova AI; Centre for Strategic Planning and Management of Biomedical Health Risks., Mitrofanov SI; Centre for Strategic Planning and Management of Biomedical Health Risks., Shingaliev AS; Centre for Strategic Planning and Management of Biomedical Health Risks., Yudin VS; Centre for Strategic Planning and Management of Biomedical Health Risks., Keskinov AA; Centre for Strategic Planning and Management of Biomedical Health Risks., Gomyranova NV; Chazov National Medical Research Center of Cardiology., Chubykina UV; Chazov National Medical Research Center of Cardiology., Ezhov MV; Chazov National Medical Research Center of Cardiology., Tereshchenko SN; Chazov National Medical Research Center of Cardiology., Yudin SM; Centre for Strategic Planning and Management of Biomedical Health Risks., Boytsov SA; Chazov National Medical Research Center of Cardiology.

Publikováno v: Terapevticheskii arkhiv [Ter Arkh] 2024 Oct 10; Vol. 96 (9), pp. 901-908. Date of Electronic Publication: 2024 Oct 10.

Benchmarking of Approaches for Gene Copy-Number Variation Analysis and Its Utility for Genetic Aberration Detection in High-Grade Serous Ovarian Carcinomas.

Autor: Grebnev PA; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical Biological Agency (Centre for Strategic Planning of FMBA of Russia), Bld. 1, Pogodinskaya Street, 10, 119121 Moscow, Russia., Meshkov IO; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical Biological Agency (Centre for Strategic Planning of FMBA of Russia), Bld. 1, Pogodinskaya Street, 10, 119121 Moscow, Russia., Ershov PV; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical Biological Agency (Centre for Strategic Planning of FMBA of Russia), Bld. 1, Pogodinskaya Street, 10, 119121 Moscow, Russia., Makhotenko AV; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical Biological Agency (Centre for Strategic Planning of FMBA of Russia), Bld. 1, Pogodinskaya Street, 10, 119121 Moscow, Russia., Azarian VB; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical Biological Agency (Centre for Strategic Planning of FMBA of Russia), Bld. 1, Pogodinskaya Street, 10, 119121 Moscow, Russia., Erokhina MV; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical Biological Agency (Centre for Strategic Planning of FMBA of Russia), Bld. 1, Pogodinskaya Street, 10, 119121 Moscow, Russia., Galeta AA; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical Biological Agency (Centre for Strategic Planning of FMBA of Russia), Bld. 1, Pogodinskaya Street, 10, 119121 Moscow, Russia., Zakubanskiy AV; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical Biological Agency (Centre for Strategic Planning of FMBA of Russia), Bld. 1, Pogodinskaya Street, 10, 119121 Moscow, Russia., Shingalieva OS; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical Biological Agency (Centre for Strategic Planning of FMBA of Russia), Bld. 1, Pogodinskaya Street, 10, 119121 Moscow, Russia., Tregubova AV; Federal State Budgetary Institution 'National Medical Research Center for Obstetrics, Gynecology and Perinatology Named after Academician V.I. Kulakov', Ministry of Healthcare of The Russian Federation, Oparina Street, Bld. 4, 117997 Moscow, Russia., Asaturova AV; Federal State Budgetary Institution 'National Medical Research Center for Obstetrics, Gynecology and Perinatology Named after Academician V.I. Kulakov', Ministry of Healthcare of The Russian Federation, Oparina Street, Bld. 4, 117997 Moscow, Russia., Yudin VS; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical Biological Agency (Centre for Strategic Planning of FMBA of Russia), Bld. 1, Pogodinskaya Street, 10, 119121 Moscow, Russia., Yudin SM; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical Biological Agency (Centre for Strategic Planning of FMBA of Russia), Bld. 1, Pogodinskaya Street, 10, 119121 Moscow, Russia., Makarov VV; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical Biological Agency (Centre for Strategic Planning of FMBA of Russia), Bld. 1, Pogodinskaya Street, 10, 119121 Moscow, Russia., Keskinov AA; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical Biological Agency (Centre for Strategic Planning of FMBA of Russia), Bld. 1, Pogodinskaya Street, 10, 119121 Moscow, Russia., Makarova AS; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical Biological Agency (Centre for Strategic Planning of FMBA of Russia), Bld. 1, Pogodinskaya Street, 10, 119121 Moscow, Russia., Snigir EA; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical Biological Agency (Centre for Strategic Planning of FMBA of Russia), Bld. 1, Pogodinskaya Street, 10, 119121 Moscow, Russia., Skvortsova VI; Federal Medical Biological Agency (FMBA of Russia), Volokolamskoye Shosse, 30, 123182 Moscow, Russia.

Publikováno v: Cancers [Cancers (Basel)] 2024 Sep 24; Vol. 16 (19). Date of Electronic Publication: 2024 Sep 24.

Characteristics of the Gut Microbiota in Regard to Atopic Dermatitis and Food Allergies of Children.

Autor: Nekrasova AI; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical and Biological Agency, Pogodinskaya Str. 10/1, 119121 Moscow, Russia., Kalashnikova IG; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical and Biological Agency, Pogodinskaya Str. 10/1, 119121 Moscow, Russia., Bobrova MM; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical and Biological Agency, Pogodinskaya Str. 10/1, 119121 Moscow, Russia., Korobeinikova AV; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical and Biological Agency, Pogodinskaya Str. 10/1, 119121 Moscow, Russia., Bakoev SY; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical and Biological Agency, Pogodinskaya Str. 10/1, 119121 Moscow, Russia., Ashniev GA; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical and Biological Agency, Pogodinskaya Str. 10/1, 119121 Moscow, Russia., Petryaikina ES; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical and Biological Agency, Pogodinskaya Str. 10/1, 119121 Moscow, Russia., Nekrasov AS; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical and Biological Agency, Pogodinskaya Str. 10/1, 119121 Moscow, Russia., Zagainova AV; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical and Biological Agency, Pogodinskaya Str. 10/1, 119121 Moscow, Russia., Lukashina MV; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical and Biological Agency, Pogodinskaya Str. 10/1, 119121 Moscow, Russia., Tolkacheva LR; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical and Biological Agency, Pogodinskaya Str. 10/1, 119121 Moscow, Russia., Zhdanova AS; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical and Biological Agency, Pogodinskaya Str. 10/1, 119121 Moscow, Russia., Mukhin VE; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical and Biological Agency, Pogodinskaya Str. 10/1, 119121 Moscow, Russia., Yudin VS; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical and Biological Agency, Pogodinskaya Str. 10/1, 119121 Moscow, Russia., Keskinov AA; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical and Biological Agency, Pogodinskaya Str. 10/1, 119121 Moscow, Russia., Makarov VV; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical and Biological Agency, Pogodinskaya Str. 10/1, 119121 Moscow, Russia., Kraevoy SA; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical and Biological Agency, Pogodinskaya Str. 10/1, 119121 Moscow, Russia., Yudin SM; Federal State Budgetary Institution 'Centre for Strategic Planning and Management of Biomedical Health Risks' of the Federal Medical and Biological Agency, Pogodinskaya Str. 10/1, 119121 Moscow, Russia.

Publikováno v: Biomedicines [Biomedicines] 2024 Mar 01; Vol. 12 (3). Date of Electronic Publication: 2024 Mar 01.

Genetics of psycho-emotional well-being: genome-wide association study and polygenic risk score analysis.

Autor: Yakovchik AY; Federal State Budgetary Institution Centre for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, Moscow, Russia., Tolynyova DV; Federal State Budgetary Institution Centre for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, Moscow, Russia., Kashtanova DA; Federal State Budgetary Institution Centre for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, Moscow, Russia., Sutulova ER; Federal State Budgetary Institution Centre for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, Moscow, Russia., Ivanov MV; Federal State Budgetary Institution Centre for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, Moscow, Russia., Mamchur AA; Federal State Budgetary Institution Centre for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, Moscow, Russia., Erema VV; Federal State Budgetary Institution Centre for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, Moscow, Russia., Matkava LR; Federal State Budgetary Institution Centre for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, Moscow, Russia., Terekhov MV; Federal State Budgetary Institution Centre for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, Moscow, Russia., Rumyantseva AM; Federal State Budgetary Institution Centre for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, Moscow, Russia., Blinova OI; Federal State Budgetary Institution Centre for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, Moscow, Russia., Akinshina AI; Federal State Budgetary Institution Centre for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, Moscow, Russia., Mitrofanov SI; Federal State Budgetary Institution Centre for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, Moscow, Russia., Yudin VS; Federal State Budgetary Institution Centre for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, Moscow, Russia., Makarov VV; Federal State Budgetary Institution Centre for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, Moscow, Russia., Keskinov AА; Federal State Budgetary Institution Centre for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, Moscow, Russia., Kraevoy SA; Federal State Budgetary Institution Centre for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, Moscow, Russia., Yudin SM; Federal State Budgetary Institution Centre for Strategic Planning and Management of Biomedical Health Risks of the Federal Medical Biological Agency, Moscow, Russia.

Publikováno v: Frontiers in psychiatry [Front Psychiatry] 2024 Jan 24; Vol. 14, pp. 1188427. Date of Electronic Publication: 2024 Jan 24 (Print Publication: 2023).