Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Yuchen Huo"'
Publikováno v:
Cell Death and Disease, Vol 14, Iss 11, Pp 1-18 (2023)
Abstract Expression of the UBE4B ubiquitin ligase is strongly associated with neuroblastoma patient outcomes, but the functional roles of UBE4B in neuroblastoma pathogenesis are not known. We evaluated interactions of UBE4B with the E3 ubiquitin liga
Externí odkaz:
https://doaj.org/article/d135c555616c4164a342e8364a8d27b5
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-23 (2022)
Abstract Background Neuroblastoma is a pediatric malignancy with a high frequency of metastatic disease at initial diagnosis. Neuroblastoma tumors have few recurrent protein-coding mutations but contain extensive somatic copy number alterations (SCNA
Externí odkaz:
https://doaj.org/article/f1c44b1412714c64a04adcfde819c8ab
Autor:
Peter E. Zage, Yuchen Huo, Divya Subramonian, Christophe Le Clorennec, Pradipta Ghosh, Debashis Sahoo
Publikováno v:
Genes, Chromosomes and Cancer. 62:313-331
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56375c3dbcfe020b5ba3299351b05f20
https://doi.org/10.1002/gcc.23124
https://doi.org/10.1002/gcc.23124
Autor:
Yuchen Huo
Publikováno v:
Tobacco Regulatory Science. 7:1087-1096
L1 signaling pathway research in different cancer types. We will also discuss the limitations of antibody-based treatments and mechanisms related to PD-1/PD-L1 blockade resistance. In the end, we will also demonstrate potential solutions to overcome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e8dca6e758f58fde50c002e0cb1c3fa
https://doi.org/10.18001/trs.7.5.26
https://doi.org/10.18001/trs.7.5.26
Publikováno v:
Cancer Research, vol 82, iss 12_Supplement
Expression of the UBE4B ubiquitin ligase is associated with neuroblastoma patient outcomes, but the functional roles of UBE4B in neuroblastoma pathogenesis are not known. We evaluated interactions of UBE4B with the E3 ubiquitin ligase ITCH/AIP4 and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a274cc7c6a8be05b56df9940b1e8f758
https://escholarship.org/uc/item/5sm5190c
https://escholarship.org/uc/item/5sm5190c
Publikováno v:
Energy Economics. 112:106184
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f5355325cc410912cf9768a54756949
https://doi.org/10.1016/j.eneco.2022.106184
https://doi.org/10.1016/j.eneco.2022.106184
Autor:
Jacqueline Lesperance, Hannah Rinehardt, Yuchen Huo, Divya Subramonian, Shixia Huang, Peter E. Zage, Jing Zhang, Qianxing Mo, Nikki Phanhthilath, Karen Messer, Sean Flynn
Publikováno v:
British journal of cancer, vol 123, iss 4
British Journal of Cancer
British Journal of Cancer
Background Regorafenib is an inhibitor of multiple kinases with aberrant expression and activity in neuroblastoma tumours that have potential roles in neuroblastoma pathogenesis. Methods We evaluated neuroblastoma cells treated with regorafenib for c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b0d2e56a1c69964b2d40d2d63fd769e
https://escholarship.org/uc/item/3zn358qs
https://escholarship.org/uc/item/3zn358qs
Autor:
Robert J. Wechsler-Reya, Jacqueline Lesperance, Peter E. Zage, Andrea Liu, Megan Rose Paul, Yuchen Huo, Alexandra Garancher
Publikováno v:
Neuro-oncology advances, vol 2, iss 1
Neuro-oncology Advances
Neuro-oncology Advances
Background Identifying mechanisms of medulloblastoma recurrence is a key to improving patient survival, and targeting treatment-resistant subpopulations within tumors could reduce disease recurrence. Expression of the granulocyte colony-stimulating f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa78cde830ad96961a305b3caaa1c143
https://pubmed.ncbi.nlm.nih.gov/32642714
https://pubmed.ncbi.nlm.nih.gov/32642714
Publikováno v:
Cancer Research. 80:4871-4871
Children with high-risk neuroblastoma have poor survival rates and need novel treatment strategies. UBE4B is an E3/E4 ubiquitin ligase whose gene is found in the chromosome 1p36 region commonly deleted in high-risk neuroblastoma tumors and whose expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67ed18a12668bacae5e0ff16eecba40d
https://doi.org/10.1158/1538-7445.am2020-4871
https://doi.org/10.1158/1538-7445.am2020-4871
Publikováno v:
Cancer Research. 80:5402-5402
Neuroblastoma is the most common extracranial solid tumor of childhood. Despite aggressive treatment, outcomes in patients with high-risk disease remains poor and new therapeutics are needed to address their needs. Rearranged during Transfection (RET
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c012f3796175afe4edd45c7d62e3b1c1
https://doi.org/10.1158/1538-7445.am2020-5402
https://doi.org/10.1158/1538-7445.am2020-5402