Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Yuchao Hao"'
Autor:
Sisi Li, Yangfan Qi, Jiachuan Yu, Yuchao Hao, Lingzhi Xu, Xudong Ding, Minghui Zhang, Jingshu Geng
Publikováno v:
Heliyon, Vol 9, Iss 7, Pp e17386- (2023)
The contribution of oncogenes to tumor-associated RNA splicing and the relevant molecular mechanisms therein require further elaboration. Here, we show that oncogenic Aurora kinase A (AURKA) promotes breast cancer-related RNA aberrant splicing in a c
Externí odkaz:
https://doaj.org/article/3871445affc4477695edf38f31e431a0
Autor:
Lu Liu, Shuyao Yang, Kefeng Lin, Xiaoman Yu, Jiaqi Meng, Chao Ma, Zheng Wu, Yuchao Hao, Ning Chen, Qi Ge, Wenli Gao, Xiang Wang, Eric W.-F. Lam, Lin Zhang, Fangcheng Li, Bilian Jin, Di Jin
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract Tumor immune microenvironment exerts a profound effect on the population of infiltrating immune cells. Tissue inhibitor of matrix metalloproteinase 1 (TIMP1) is frequently overexpressed in a variety of cells, particularly during inflammation
Externí odkaz:
https://doaj.org/article/3e6c09f24c63412a89b66e4fab5dbc27
Autor:
SiSi Li, YangFan Qi, JiaChuan Yu, YuChao Hao, Bin He, MengJuan Zhang, ZhenWei Dai, TongHui Jiang, SuYi Li, Fang Huang, Ning Chen, Jing Wang, MengYing Yang, DaPeng Liang, Fan An, JinYao Zhao, WenJun Fan, YuJia Pan, ZiQian Deng, YuanYuan Luo, Tao Guo, Fei Peng, ZhiJie Hou, ChunLi Wang, FeiMeng Zheng, LingZhi Xu, Jie Xu, QingPing Wen, BiLian Jin, Yang Wang, Quentin Liu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-15 (2022)
Abstract Aberrant RNA splicing produces alternative isoforms of genes to facilitate tumor progression, yet how this process is regulated by oncogenic signal remains largely unknown. Here, we unveil that non-canonical activation of nuclear AURKA promo
Externí odkaz:
https://doaj.org/article/f51cec2a13fb480aa35e26ccc9c97976
Autor:
Jiacheng Lou, Yuchao Hao, Kefeng Lin, Yizhu Lyu, Meiwei Chen, Han Wang, Deyu Zou, Xuewen Jiang, Renchun Wang, Di Jin, Eric W.-F. Lam, Shujuan Shao, Quentin Liu, Jinsong Yan, Xiang Wang, Puxiang Chen, Bo Zhang, Bilian Jin
Publikováno v:
Molecular Cancer, Vol 19, Iss 1, Pp 1-19 (2020)
Abstract Background Inactivation of the tumor suppressor p53 is critical for pathogenesis of glioma, in particular glioblastoma multiforme (GBM). MDM2, the main negative regulator of p53, binds to and forms a stable complex with p53 to regulate its a
Externí odkaz:
https://doaj.org/article/9a8bd3c14d3f414887b3d070b73c045d
Publikováno v:
Journal of Physics: Conference Series; 2024, Vol. 2764 Issue 1, p1-8, 8p
Autor:
Kefeng Lin, Wenli Gao, Ning Chen, Han Wang, Ran Wang, Shuyao Yang, Fang Xie, Jiaqi Meng, Eric W.-F. Lam, Chao Ma, Suyi Li, Ning Kang, Yuchao Hao, Zheng Wu, Qi Ge, Lili Guo, Wei Cheng, Puxiang Chen, Hongjin Wu, Jinsong Yan, Di Jin, Bilian Jin
Background Without an effective strategy for targeted therapy, glioblastoma multiforme (GBM) is still incurable, with a median survival of only 15 months. Both chronic inflammation and epigenetic reprogramming are hallmarks of cancer. However, the me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::270716b3bc65ad5ce51c05cdd217a272
https://doi.org/10.21203/rs.3.rs-1394307/v1
https://doi.org/10.21203/rs.3.rs-1394307/v1
Autor:
SiSi, Li, YangFan, Qi, JiaChuan, Yu, YuChao, Hao, Bin, He, MengJuan, Zhang, ZhenWei, Dai, TongHui, Jiang, SuYi, Li, Fang, Huang, Ning, Chen, Jing, Wang, MengYing, Yang, DaPeng, Liang, Fan, An, JinYao, Zhao, WenJun, Fan, YuJia, Pan, ZiQian, Deng, YuanYuan, Luo, Tao, Guo, Fei, Peng, ZhiJie, Hou, ChunLi, Wang, FeiMeng, Zheng, LingZhi, Xu, Jie, Xu, QingPing, Wen, BiLian, Jin, Yang, Wang, Quentin, Liu
Publikováno v:
Signal transduction and targeted therapy. 7(1)
Aberrant RNA splicing produces alternative isoforms of genes to facilitate tumor progression, yet how this process is regulated by oncogenic signal remains largely unknown. Here, we unveil that non-canonical activation of nuclear AURKA promotes an on
Publikováno v:
The Journal of Chemical Thermodynamics. 132:423-431
The thermal properties of hydrate-bearing sediments can help to evaluate the stability of hydrate reservoir and improve the safety of natural gas hydrate exploitation. In this work, the thermal conductivities of methane hydrate and methane hydrate-be
Autor:
Jiacheng Lou, Yuchao Hao, Kefeng Lin, Yizhu Lyu, Meiwei Chen, Wang, Han, Deyu Zou, Xuewen Jiang, Renchun Wang, Jin, Di, Lam, Eric W.-F., Shujuan Shao, Liu, Quentin, Jinsong Yan, Wang, Xiang, Puxiang Chen, Zhang, Bo, Jin, Bilian
Additional file 9 Figure S8. CDR1as serves as a protective machinery to preserve p53 function against DNA damage in LN229 cells. A. Western blot analysis of p53 and p21 expression (left), and RT-qPCR analysis of CDR1as expression (right) in LN229 cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::722a68a1f657123a833151c1c4c17874
Autor:
Jiacheng Lou, Yuchao Hao, Kefeng Lin, Yizhu Lyu, Meiwei Chen, Wang, Han, Deyu Zou, Xuewen Jiang, Renchun Wang, Jin, Di, Lam, Eric W.-F., Shujuan Shao, Liu, Quentin, Jinsong Yan, Wang, Xiang, Puxiang Chen, Zhang, Bo, Jin, Bilian
Additional file 10 Figure S9. Ubiquitination of p53 in U87MG cells without MG132 treatment. A. Immunoblot of p53 ubiquitination in U87MG cells co-transfected with the plasmids encoding HA-Ub, Myc-MDM2 and CDR1as without MG132 treatment. B. Immunoblot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26c93b3bdee25966c8420cc9edbc880b