Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Yuchang Fu"'
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 7, Pp 1369-1379 (2005)
Adiponectin is secreted from adipocytes, and low circulating levels have been epidemiologically associated with obesity, insulin resistance, type 2 diabetes, and cardiovascular disease. To investigate whether adiponectin could exert autocrine effects
Externí odkaz:
https://doaj.org/article/696401c1ca04405ba6f8bff617b3e72d
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 7, Pp 1315-1321 (2003)
We have previously shown that LDL-containing immune complexes (LDL-ICs) induce up-regulation of LDL receptor (LDLR) expression in human macrophages. The present study further investigated the molecular mechanisms leading to LDLR up-regulation by LDL-
Externí odkaz:
https://doaj.org/article/464d62fc43674ffe98d04f6772485409
Autor:
Weina Gao, Yuchang Fu, Cong Yu, Shunke Wang, Yuchao Zhang, Chen Zong, Tongfu Xu, Yong Liu, Xia Li, Xiangdong Wang
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91462 (2014)
BACKGROUND: NR4A3/NOR-1 is a member of the NR4A orphan nuclear receptor subfamily, which contains early response genes that sense and respond to a variety of stimuli in the cellular environment. The role of NR4A3 in insulin expression in pancreatic b
Externí odkaz:
https://doaj.org/article/ca7d8ce67d0c4a0ebc9f459db4a344a1
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 12, Pp 2017-2023 (2000)
The adipocyte lipid-binding protein (ALBP/aP2) belongs to a multigene family of fatty acid and retinoid transport proteins. This protein is abundantly expressed in the cytoplasm and nuclear region of adipocytes and is postulated to serve as a lipid s
Externí odkaz:
https://doaj.org/article/fd2a7a23c2ca4bee8156bd6e33021f23
Autor:
Guo-Jun Zhao, Shi-Lin Tang, Yun-Cheng Lv, Xin-Ping Ouyang, Ping-Ping He, Feng Yao, Wu-Jun Chen, Qian Lu, Yan-Yan Tang, Min Zhang, Yuchang Fu, Da-Wei Zhang, Kai Yin, Chao-Ke Tang
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74782 (2013)
ATP-binding cassette transporter A1 (ABCA1) is critical in exporting cholesterol from macrophages and plays a protective role in the development of atherosclerosis. The purpose of this study was to investigate the effects of betulinic acid (BA), a pe
Externí odkaz:
https://doaj.org/article/65783c77405b48c1aff7e5965ed1f642
Autor:
Elizabeth B. Heywood, R. Grace Walton, Helliner S. Hill, W. Timothy Garvey, Qinglin Yang, Ling Tian, Xiaolin Zhu, Yuchang Fu, Jiarong Liu, Jian Liu, Dennis Bruemmer
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 311:E69-E81
The NR4A orphan nuclear receptors function as early response genes to numerous stimuli. Our laboratory has previously demonstrated that overexpression of NR4A3 (NOR-1, MINOR) in 3T3-L1 adipocytes enhances insulin-stimulated glucose uptake. To assess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9ed61e455df0f3a2b74981277325ea0
https://doi.org/10.1152/ajpendo.00330.2015
https://doi.org/10.1152/ajpendo.00330.2015
Autor:
Minsung Kang, Teayoun Kim, Qinglin Yang, Dennis Steverson, W. Timothy Garvey, W. John Garvey, Wei Zhang, Ling Tian, Yuchang Fu, Elizabeth Ma, Nanlan Luo, Mengrui Wu, Ravi H. Jariwala
Publikováno v:
Diabetes
In the current study, we used muscle-specific TRIB3 overexpressing (MOE) and knockout (MKO) mice to determine whether TRIB3 mediates glucose-induced insulin resistance in diabetes and whether alterations in TRIB3 expression as a function of nutrient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf700c0d048faa8b67da256349e04bab
https://doi.org/10.2337/db16-0154
https://doi.org/10.2337/db16-0154
Publikováno v:
Metabolic Syndrome and Related Disorders. 14:7-15
Insulin resistance is central in the pathophysiology of cardiometabolic disease; however, common mechanisms that explain the parallel development of both type 2 diabetes and atherosclerosis have not been elucidated. We have previously shown that trib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cda5817bb1960083a63ed566dbc7edc9
https://doi.org/10.1089/met.2015.0037
https://doi.org/10.1089/met.2015.0037
Publikováno v:
Metabolic syndrome and related disorders. 16(2)
Background: Insulin resistance disrupts metabolic processes and leads to various chronic disease states such as diabetes and metabolic syndrome (MetS). However, the mechanism linking insulin resistance with cardiometabolic disease pathophysiology is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772441557d6832772ea8ada934f5df6f
https://pubmed.ncbi.nlm.nih.gov/29360415
https://pubmed.ncbi.nlm.nih.gov/29360415
Autor:
Yuchang Fu, Yuantao Liu, Dandan Qin, Jicui Chen, Tongfu Xu, Cong Yu, Qingbo Guan, Xiangdong Wang, Chen Zong, Xia Li, Peng Gao, Weina Gao, Shang Cui
Publikováno v:
The Journal of Biological Chemistry
Background: It is not known whether NR4A1 plays a role in ER stress-induced β-cell apoptosis. Results: NR4A1 expression in β-cells or islets correlated positively with Survivin expression and negatively with CHOP expression and apoptosis rate upon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b219d4d6d10d1cbb1f378e938d2200e4
http://europepmc.org/articles/PMC4543630
http://europepmc.org/articles/PMC4543630