Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Yucen Xia"'
Autor:
Chaofan Wan, Yucen Xia, Jinglan Yan, Weipeng Lin, Lin Yao, Meng Zhang, Inna Gaisler-Salomon, Lin Mei, Dong-Min Yin, Yongjun Chen
Publikováno v:
Cell Death and Disease, Vol 15, Iss 2, Pp 1-15 (2024)
Abstract Neuronal nitric oxide synthase (nNOS, gene name Nos1) orchestrates the synthesis of nitric oxide (NO) within neurons, pivotal for diverse neural processes encompassing synaptic transmission, plasticity, neuronal excitability, learning, memor
Externí odkaz:
https://doaj.org/article/f7e94508b80e42abaa5888bb60e19ca6
Autor:
Yuanjia Zheng, Lingyun Pan, Feixue Wang, Jinglan Yan, Taiyi Wang, Yucen Xia, Lin Yao, Kelin Deng, Yuqi Zheng, Xiaoye Xia, Zhikai Su, Hongjie Chen, Jie Lin, Zhenwei Ding, Kaitong Zhang, Meng Zhang, Yongjun Chen
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract Bmal1 (Brain and muscle arnt-like, or Arntl) is a bHLH/PAS domain transcription factor central to the transcription/translation feedback loop of the biologic clock. Although Bmal1 is well-established as a major regulator of circadian rhythm,
Externí odkaz:
https://doaj.org/article/2609853fe76e4e6fb0c8dee53d61f997
Autor:
Yiwen Chen, Yuanjia Zheng, Jinglan Yan, Chuanan Zhu, Xuan Zeng, Shaoyi Zheng, Wenwen Li, Lin Yao, Yucen Xia, Wei-wei Su, Yongjun Chen
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2022)
Early life stress is thought to be a risk factor for emotional disorders, particularly depression and anxiety. Although the excitation/inhibition (E/I) imbalance has been implicated in neuropsychiatric disorders, whether early life stress affects the
Externí odkaz:
https://doaj.org/article/1d317656294e4df89fb63529d3d0413b
Autor:
Xiumin Jiang, Yongxin Luo, Yiwen Chen, Jinglan Yan, Yucen Xia, Lin Yao, Xiaotong Wang, Su He, Feixue Wang, Taiyi Wang, Yongjun Chen
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 15 (2021)
Background: Subthreshold depression (SD) is considered to be the precursor stage of major depression, which is correlated with functional impairment and increased suicide rate. Although there are multiple therapies for the treatment of SD, the compar
Externí odkaz:
https://doaj.org/article/1747802b030e435c99410cae8c27c7fc
Autor:
Yuanjia Zheng, Xiumin Jiang, Yacen Gao, Lexin Yuan, Xiaotong Wang, Shengwei Wu, Yucen Xia, Lin Yao, Jinglan Yan, Lanying Liu, Yingdong Wei, Zhiqiang Song, Lin Yu, Yongjun Chen
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Antipsychotic-related constipation (APRC) is one of the most common side effects of taking antipsychotic medication. APRC can seriously impact patient quality of life and is potentially fatal, though the efficacy of current APRC treatments is low for
Externí odkaz:
https://doaj.org/article/13e9ead0059040409b423f548446028a
Autor:
Chaofan Wan, Yunlong Xu, Baoyan Cen, Yucen Xia, Lin Yao, Yuanjia Zheng, Jiaying Zhao, Su He, Yongjun Chen
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Chronic inflammatory pain is a severe clinical symptom that aggravates the life quality of patients and places a huge economic burden on individuals and society. As one complementary and alternative therapy, electroacupuncture (EA) is widely used in
Externí odkaz:
https://doaj.org/article/d060825fb9694f719f0d608a399b974a
Autor:
Hong Cheng, Tian Lu, Jingya Wang, Yucen Xia, Xiaoshu Chai, Minyi Zhang, Yutong Yao, Na Zhou, Sisi Zhou, Xinyi Chen, Weiwei Su, Cunzhi Liu, Wei Yi, Yongjun Chen, Lin Yao
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Hyperglycemia induces vascular endothelial dysfunction, which contributes to the development of vascular complication of diabetes. A classic prescription of traditional medicine, HuangqiGuizhiWuwu Decoction (HGWWD) has been used for the treatment of
Externí odkaz:
https://doaj.org/article/c8077c7811184562acee2370c72dfce5
Autor:
Yuanjia Zheng, Jiang He, Lili Guo, Lin Yao, Xiaorong Zheng, Zhihua Yang, Yucen Xia, Xiaoli Wu, Yang Su, Nenggui Xu, Yongjun Chen
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Maternal separation (MS), a stressful event in early life, has been linked to neuropsychiatric disorders later in life, especially depression. In this study we investigated whether treatment with electroacupuncture (EA) could ameliorate depression-re
Externí odkaz:
https://doaj.org/article/8114eff1088b4b24965b73d8ac8a7865
Autor:
Hongzhu Li, Jiaying Zhao, Lanfeng Lai, Yucen Xia, Chaofan Wan, Shen Wei, Jiaming Liang, Yongjun Chen, Nenggui Xu
Publikováno v:
Neurobiology of Aging. 117:165-178
Neuropsychiatric symptoms, such as anxiety and depression often appear early in patients with Alzheimer's disease (AD), and a comorbid, anxiety-like phenotype is also found in rodents with AD. However, the underlying mechanisms behind these condition
Autor:
Yongjun Chen, Ruth B. Caldwell, Guoqi Shi, Hang Lv, Chuan’an Zhu, Robert W. Caldwell, Hui Ni, Zhixing Li, Lin Yao, Jiating Lian, Ruolin Wu, Yucen Xia, Yunlong Xu
Publikováno v:
Journal of Psychiatric Research. 114:55-66
Chronic stress-induced anxiety disorder is a highly-prevalent, modern social disease in which oxidative stress plays an important role. It is necessary to determine the underlying mechanisms governing this disorder to establish an effective treatment