Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Yucel Erbilgin"'
Autor:
Egzona Qipa, Muradiye Acar, Sureyya Bozkurt, Murat Buyukdogan, Hazal Berivan Sonmez, Muge Sayitoglu, Yucel Erbilgin, Zeynep Karakas, Veysel Sabri Hancer
Publikováno v:
Mediterranean Journal of Hematology and Infectious Diseases, Vol 15, Iss 1 (2023)
Acute lymphoblastic leukemia (ALL) is a malignant disease of hematopoietic stem cells. B cell ALL (B-ALL) is characterized by highly proliferative and poorly differentiated progenitor B cells in the bone marrow. Chromosomal rearrangements, aberrant c
Externí odkaz:
https://doaj.org/article/150a0d3f6259467883af1196f929c0a0
Autor:
Ozden Hatirnaz Ng, Ilayda Sahin, Yucel Erbilgin, Ozkan Ozdemir, Emrah Yucesan, Nazli Erturk, Merve Yemenici, Ozlem Akgun Dogan, Sibel Aylin Ugur Iseri, Ilhan Satman, Yasemin Alanay, Ugur Ozbek
Publikováno v:
Frontiers in Public Health, Vol 10 (2023)
Rare disease patients constitute a significant part of the healthcare system of all countries. However, the information on the experiences during disease processes and daily life of rare disease patients is still limited. So far, there is a small num
Externí odkaz:
https://doaj.org/article/04f3831b7dfa494d8f90a8d3bad42d91
Autor:
Jusuf Imeri, Christophe Desterke, Paul Marcoux, Gladys Telliam, Safa Sanekli, Sylvain Barreau, Yucel Erbilgin, Theodoros Latsis, Patricia Hugues, Nathalie Sorel, Emilie Cayssials, Jean-Claude Chomel, Annelise Bennaceur-Griscelli, Ali G. Turhan
Publikováno v:
Cells, Vol 12, Iss 4, p 598 (2023)
Purpose: To model CML progression in vitro and generate a blast crisis (BC-CML) model in vitro in order to identify new targets. Methods: Three different CML-derived iPSC lines were mutagenized with the alkylating agent ENU on a daily basis for 60 da
Externí odkaz:
https://doaj.org/article/68ca13524a4b4e71bf4f8c1f1278d1db
Autor:
Tugce Sudutan, Yucel Erbilgin, Ozden Hatirnaz Ng, Serap Karaman, Zeynep Karakas, Fulya Kucukcankurt, Tiraje Celkan, Cetin Timur, Gul Nihal Ozdemir, Sadan Hacısalihoglu, Sema Aylan Gelen, Müge Sayitoğlu
Publikováno v:
Leukemia & Lymphoma. 63:2931-2939
B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is a heterogeneous malignancy and consists of several genetic abnormalities. Some of these abnormalities are used in clinics for risk calculation and treatment decisions. Patients with ZNF384 re
Autor:
Sinem Firtina, Yucel Erbilgin, Ozden Hatirnaz Ng, Serap Karaman, Zeynep Karakas, Tulin Tiraje Celkan, Sema Aylan Gelen, Yildiz Yildirmak, Ugur Ozbek, Muge Sayitoglu
The tumor suppressor protein 53 (TP53) gene is one of the most studied genes in cancer. Although TP53 variants are rare events in acute leukemia, recent observations showed that relapse samples might harbor TP53 variants. Here, we aimed to determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae7e388715082e53d1526f628721698a
Autor:
Deniz Tugcu, Khusan Khodzhaev, Tiraje Celkan, Zeynep Karakas, Yıldız Yildirmak, Yucel Erbilgin, Ozden Hatirnaz Ng, Yuk Yin Ng, Gül Nihal Özdemir, Cetin Timur, Muge Sayitoglu
Publikováno v:
International Journal of Laboratory Hematology. 42:581-588
Autor:
Sema Aylan Gelen, Tülin Tiraje Celkan, Ismail Can, Muge Sayitoglu, Emine Zengin, Ozden Hatirnaz Ng, Ozlem Toluk, Khusan Khodzhaev, Zeynep Karakas, Yıldız Yildirmak, Sinem Firtina, Omer Dogru, Fulya Küçükcankurt, Ugur Ozbek, Gül Nihal Özdemir, Yucel Erbilgin, Turkan Tansel, Serap Karaman
Introduction: The lymphoid enhancer factor 1 (LEF1) is a DNA-binding transcription factor that functions in the Wnt signaling pathway. Increased LEF1 activity is associated with progression of several types of cancer including leukemia. Here, we inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f17273034825cb434e8e2a11cf187f7d
https://hdl.handle.net/20.500.12713/1691
https://hdl.handle.net/20.500.12713/1691
Publikováno v:
Istanbul University Institute of Health Sciences Journal of Advanced Research in Health Sciences. 3
Objective: Impaired activation of the PI3K/AKT signaling pathway has been associated with tumor development. The PTEN/AKT pathway plays a critical role in cell growth and survival and has been associated with chemotherapy resistance in leukemia. In t
Autor:
Ozden Hatirnaz, Ugur Ozbek, Muge Sayitoglu, Sinem Firtina, Ayşegül Ünüvar, Yucel Erbilgin, Zeynep Karakas, Fulya Küçükcankurt, Tiraje Celkan
Publikováno v:
Turkish Journal of Hematology
Turkish Journal of Hematology, Vol 37, Iss 2, Pp 98-103 (2020)
Turkish Journal of Hematology, Vol 37, Iss 2, Pp 98-103 (2020)
Objective: PTEN/AKT pathway deregulations have been reported to be associated with treatment response in acute leukemia. This study examined pediatric T-cell acute lymphoblastic leukemia (T-ALL) samples for PTEN and AKT1 gene variations and evaluated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::437738789b68b734f73d7d7299d7ddb4
https://hdl.handle.net/20.500.12939/268
https://hdl.handle.net/20.500.12939/268
Autor:
Rejin Kebudi, Merve Sarıtaş, Muge Sayitoglu, Ceyhun Bozkurt, Khusan Khodzhaev, Yucel Erbilgin
Publikováno v:
Blood. 138:4490-4490
Objective Hodgkin lymphoma (HL) is a lymphoproliferative malignancy of B-cell origin and one of the common tumors in adolescent and young adults. Less than one percent of HL patients have a family history and siblings of the affected individual may h