Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Yucel Aydin"'
Autor:
Kelley G. Núñez, Dorota Wyczechowska, Mina Hibino, Tyler Sandow, Juan Gimenez, Ali R. Koksal, Yucel Aydin, Srikanta Dash, Ari J. Cohen, Paul T. Thevenot
Publikováno v:
Livers, Vol 3, Iss 4, Pp 727-738 (2023)
Translational strategies to characterize and monitor extracellular vesicles such as exosome (EX) shedding and the clinical impact of this data within hepatocellular carcinoma (HCC) remains unclear. In this study, EX shedding was assessed in early-sta
Externí odkaz:
https://doaj.org/article/fc31f9d376d44bbe847e34ac33c60eef
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background Chronic hepatitis C virus (HCV) infection causes hepatocellular carcinoma (HCC). The HCC risk, while decreased compared with active HCV infection, persists in HCV-cured patients by direct-acting antiviral agents (DAA). We previous
Externí odkaz:
https://doaj.org/article/4ebdc79139664e46997b83b5df186132
Autor:
Jeffrey Wang, Mohamed A. Ghonim, Salome V. Ibba, Hanh H. Luu, Yucel Aydin, Peter A. Greer, A. Hamid Boulares
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Background We reported that PARP-1 regulates genes whose products are crucial for asthma, in part, by controlling STAT6 integrity speculatively through a calpain-dependent mechanism. We wished to decipher the PARP-1/STAT6 relationship in the
Externí odkaz:
https://doaj.org/article/06e8d087c8bf469fa6f8d3b011c19b21
Autor:
Yucel Aydin, Milad Chedid, Srinivas Chava, Donkita Danielle Williams, Shuanghu Liu, Curt H. Hagedorn, Suchitra Sumitran-Holgersson, Krzysztof Reiss, Krzysztof Moroz, Hua Lu, Luis A. Balart, Srikanta Dash
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/037008dbf48c417497970994ce74207f
Autor:
Yucel Aydin, Milad Chedid, Srinivas Chava, Donkita Danielle Williams, Shuanghu Liu, Curt H. Hagedorn, Suchitra Sumitran-Holgersson, Krzysztof Reiss, Krzysztof Moroz, Hua Lu, Luis A. Balart, Srikanta Dash
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract The mechanism of how chronic hepatitis C virus (HCV) infection leads to such a high rate of hepatocellular carcinoma (HCC) is unknown. We found that the PERK axis of endoplasmic reticulum (ER) stress elicited prominent nuclear translocation
Externí odkaz:
https://doaj.org/article/1c273bda27a2435b98c2b3064a561524
Autor:
Dong Lin, Venu Reddy, Hanadi Osman, Adriana Lopez, Ali Riza Koksal, Sadeq Mutlab Rhadhi, Srikanta Dash, Yucel Aydin
Publikováno v:
Cells, Vol 10, Iss 4, p 790 (2021)
Chronic hepatitis C virus (HCV) infection causes hepatocellular carcinoma (HCC). Although HCV clearance has been improved by the advent of direct-acting antiviral agents (DAA), retrospective studies have shown that the risk of subsequent HCC, while c
Externí odkaz:
https://doaj.org/article/29dc185203bd44eebfe18f2295a2c799
Autor:
Yucel Aydin, Ali Riza Koksal, Venu Reddy, Dong Lin, Hanadi Osman, Zahra Heidari, Sadeq Mutlab Rhadhi, William C Wimley, Mansour A Parsi, Srikanta Dash
Publikováno v:
Cells, Vol 10, Iss 5, p 984 (2021)
Hepatitis C virus (HCV) infection promotes autophagic degradation of viral replicative intermediates for sustaining replication and spread. The excessive activation of autophagy can induce cell death and terminate infection without proper regulation.
Externí odkaz:
https://doaj.org/article/9c128733ad0041a1ad2387344857fbe4
Publikováno v:
Cells, Vol 8, Iss 11, p 1308 (2019)
Hepatitis C virus (HCV) infection triggers autophagy processes, which help clear out the dysfunctional viral and cellular components that would otherwise inhibit the virus replication. Increased cellular autophagy may kill the infected cell and termi
Externí odkaz:
https://doaj.org/article/06db2142bf184fb1bb2091fb501d9c33
Autor:
Ramazan Kurt, Partha K Chandra, Fatma Aboulnasr, Rajesh Panigrahi, Pauline Ferraris, Yucel Aydin, Krzysztof Reiss, Tong Wu, Luis A Balart, Srikanta Dash
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125962 (2015)
Hepatic steatosis is a risk factor for both liver disease progression and an impaired response to interferon alpha (IFN-α)-based combination therapy in chronic hepatitis C virus (HCV) infection. Previously, we reported that free fatty acid (FFA)-tre
Externí odkaz:
https://doaj.org/article/b09bdfa651ce47c298991a25edbf6278
Autor:
Srikanta Dash, Srinivas Chava, Yucel Aydin, Partha K. Chandra, Pauline Ferraris, Weina Chen, Luis A. Balart, Tong Wu, Robert F. Garry
Publikováno v:
Viruses, Vol 8, Iss 5, p 150 (2016)
Hepatitis C virus (HCV) infection frequently leads to chronic liver disease, liver cirrhosis and hepatocellular carcinoma (HCC). The molecular mechanisms by which HCV infection leads to chronic liver disease and HCC are not well understood. The infec
Externí odkaz:
https://doaj.org/article/855a52a7c8bb43a3ba63ed507abe214b