Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Yuben P Moodley"'
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Akademický článek
Transcriptional profiling of circulating mononuclear cells from patients with chronic obstructive pulmonary disease receiving mesenchymal stromal cell infusions
Autor: Jesse D. Armitage, Dino B.A. Tan, Marian Sturm, Yuben P. Moodley
Publikováno v: Stem Cells Translational Medicine, Vol 10, Iss 11, Pp 1470-1481 (2021)
Abstract Chronic obstructive pulmonary disease (COPD) is an inflammatory airways disease with limited therapeutic options. We have previously shown that mesenchymal stromal cell (MSC) infusions are well tolerated in patients with COPD and reduce circ
Externí odkaz: https://doaj.org/article/18f1147aafa74e328ed0b8b1da57680c
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2
Idiopathic pulmonary fibrosis is associated with common genetic variants and limited rare variants
Autor: Anna L. Peljto, Rachel Z. Blumhagen, Avram D. Walts, Jonathan Cardwell, Julia Powers, Tamera J. Corte, Joanne L. Dickinson, Ian Glaspole, Yuben P. Moodley, Martina Koziar Vasakova, Elisabeth Bendstrup, Jesper R. Davidsen, Raphael Borie, Bruno Crestani, Philippe Dieude, Francesco Bonella, Ulrich Costabel, Gunnar Gudmundsson, Seamas C. Donnelly, Jim Egan, Michael T. Henry, Michael P. Keane, Marcus P. Kennedy, Cormac McCarthy, Aoife N. McElroy, Joshua A. Olaniyi, Katherine M. A. O’Reilly, Luca Richeldi, Paolo M. Leone, Venerino Poletti, Francesco Puppo, Sara Tomassetti, Valentina Luzzi, Nurdan Kokturk, Nesrin Mogulkoc, Christine A. Fiddler, Nikhil Hirani, R. Gisli Jenkins, Toby M. Maher, Philip L. Molyneaux, Helen Parfrey, Rebecca Braybrooke, Timothy S. Blackwell, Peter D. Jackson, Steven D. Nathan, Mary K. Porteous, Kevin K. Brown, Jason D. Christie, Harold R. Collard, Oliver Eickelberg, Elena E. Foster, Kevin F. Gibson, Marilyn Glassberg, Daniel J. Kass, Jonathan A. Kropski, David Lederer, Angela L. Linderholm, Jim Loyd, Susan K. Mathai, Sydney B. Montesi, Imre Noth, Justin M. Oldham, Amy J. Palmisciano, Cristina A. Reichner, Mauricio Rojas, Jesse Roman, Neil Schluger, Barry S. Shea, Jeffrey J. Swigris, Paul J. Wolters, Yingze Zhang, Cecilia M. A. Prele, Juan I. Enghelmayer, Maria Otaola, Christopher J. Ryerson, Mauricio Salinas, Martina Sterclova, Tewodros H. Gebremariam, Marjukka Myllärniemi, Roberto G. Carbone, Haruhiko Furusawa, Masaki Hirose, Yoshikazu Inoue, Yasunari Miyazaki, Ken Ohta, Shin Ohta, Tsukasa Okamoto, Dong Soon Kim, Annie Pardo, Moises Selman, Alvaro U. Aranda, Moo Suk Park, Jong Sun Park, Jin Woo Song, Maria Molina-Molina, Lurdes Planas-Cerezales, Gunilla Westergren-Thorsson, Albert V. Smith, Ani W. Manichaikul, John S. Kim, Stephen S. Rich, Elizabeth C. Oelsner, R. Graham Barr, Jerome I. Rotter, Josee Dupuis, George O’Connor, Ramachandran S. Vasan, Michael H. Cho, Edwin K. Silverman, Marvin I. Schwarz, Mark P. Steele, Joyce S. Lee, Ivana V. Yang, Tasha E. Fingerlin, David A. Schwartz
Rationale: Idiopathic pulmonary fibrosis is a rare, irreversible, and progressive disease of the lungs. Common genetic variants, in addition to non-genetic factors, have been consistently associated with IPF. Rare variants identified by candidate gen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0670c24aedc8efa23979477ed15d39b
http://hdl.handle.net/10044/1/101620
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4
Circulating cell-free double-stranded DNA and metabolic derangements in idiopathic pulmonary fibrosis: a new association
Autor: Yuben P, Moodley
Publikováno v: Thorax
Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease with unclear aetiology and poorly understood pathophysiology. Although plasma levels of circulating cell-free DNA (ccf-DNA) and metabolomic changes have been reported in IPF,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcd1c9818efb8607d812c8da468f5a91
https://doi.org/10.1136/thoraxjnl-2021-218192
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Increased CTLA-4
Autor: Dino B A, Tan, Teck-Hui, Teo, Abdul M, Setiawan, Nathanael E, Ong, Maja, Zimmermann, Patricia, Price, Lea-Ann S, Kirkham, Yuben P, Moodley
Publikováno v: Immunology. 151(2)
Impaired T helper type 1 (Th1) function is implicated in the susceptibility of patients with chronic obstructive pulmonary disease (COPD) to respiratory infections, which are common causes of acute exacerbations of COPD (AECOPD). To understand the un
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::84da6b34a8056b4c200d9680dd3a2a2d
https://pubmed.ncbi.nlm.nih.gov/28190271
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6
Health-related quality of life in idiopathic pulmonary fibrosis: Data from the Australian IPF Registry
Autor: Ian N, Glaspole, Sally A, Chapman, Wendy A, Cooper, Samantha J, Ellis, Nicole S, Goh, Peter M, Hopkins, Sacha, Macansh, Annabelle, Mahar, Yuben P, Moodley, Eldho, Paul, Paul N, Reynolds, E Haydn, Walters, Christopher J, Zappala, Tamera J, Corte
Publikováno v: Respirology (Carlton, Vic.). 22(5)
Studies analysing the effect of worsening pulmonary physiological impairment in idiopathic pulmonary fibrosis (IPF) with respect to quality of life have been limited to single centres or highly selected trial populations. The aim of this study was to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::19937875e44999a598ac91bdd87a450a
https://pubmed.ncbi.nlm.nih.gov/28544193
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Oncostatin M stimulates proliferation, induces collagen production and inhibits apoptosis of human lung fibroblasts
Autor: Amelia K, Scaffidi, Steven E, Mutsaers, Yuben P, Moodley, Robin J, McAnulty, Geoffrey J, Laurent, Philip J, Thompson, Darryl A, Knight
Publikováno v: British journal of pharmacology. 136(5)
1. Oncostatin M (OSM), a member of the interleukin-6 (IL-6) cytokine family, acts on a variety of cells and elicits diversified biological responses, suggesting potential roles in the regulation of cell survival, differentiation and proliferation. 2.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dfc1dd33ff61c0574295f567bab8d0da
https://pubmed.ncbi.nlm.nih.gov/12086989
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9
Correlation of CD4:CD8 ratio and tumour necrosis factor (TNF)α levels in induced sputum with bronchoalveolar lavage fluid in pulmonary sarcoidosis
Autor: Umesh G. Lalloo, Salosh Venketasamy, Trevor Dorasamy, Yuben P. Moodley, Vincent Naicker
BACKGROUND—An increased CD4:CD8 lymphocyte ratio and raised cytokine levels in bronchoalveolar lavage (BAL) fluid are characteristic of pulmonary sarcoidosis. Sputum induction has been used as a non-invasive tool for investigating the airways and m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f2d1c2d6923c6044290abfd3ec2dbbc
https://europepmc.org/articles/PMC1745837/
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10
Neutrophils in induced sputum arise from central airways
Autor: Yuben P. Moodley, Umesh G. Lalloo, V Krishnan
Publikováno v: The European respiratory journal. 15(1)
A high neutrophil count is often found in induced sputum compared to bronchoalveolar lavage fluid (BALF). This study investigated whether such a high neutrophil count may be a response to inhaled hypertonic saline or that the airway compartment sampl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9b0b6561bd9bab580caf029a2b130ea
https://pubmed.ncbi.nlm.nih.gov/10678618
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