Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Yubao Shao"'
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background and purpose Interstitial lung disease (ILD) represents a significant complication of rheumatoid arthritis (RA) that lacks effective treatment options. This study aimed to investigate the intrinsic mechanism by which resveratrol at
Externí odkaz:
https://doaj.org/article/55d8e95e01604e6bbe9079b1d5cf0b28
Autor:
Ziqing YAN, Wenjie SHI, Pengtao ZHANG, Yongjun WANG, Yubao SHAO, Xin HUANG, Yu SONG, Jun TAN, Zhihua WANG
Publikováno v:
地质科技通报, Vol 43, Iss 2, Pp 156-174 (2024)
Objective The Dayingezhuang gold deposit in the middle of the Zhaoping metallogenic belt represents a typical altered-rock type deposit with a giant Au reserve of 283 tons on the Jiaodong Peninsula. The genetic type of the deposit is still controvers
Externí odkaz:
https://doaj.org/article/e4d3859e2c2f4b35ae09d1138180eaca
Autor:
Chuanxu Liu, Xinyu Ding, Gaoyang Li, Youping Zhang, Yubao Shao, Linyi Liu, Wenhao Zhang, Yujie Ma, Wenbin Guan, Lifeng Wang, Zhongli Xu, YungTing Chang, Yongqiang Zhang, Biao Jiang, Qianqian Yin, Rong Tao
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107369- (2023)
Summary: Extranodal natural killer/T cell lymphoma, nasal type (ENKTL) is an aggressive lymphoid malignancy with a poor prognosis and lacks standard treatment. Targeted therapies are urgently needed. Here we systematically investigated the druggable
Externí odkaz:
https://doaj.org/article/ccbdfdb490734274a1521bd8d01d1dc2
Autor:
Yubao Shao, Huaihong Wang, Yinghai Guo, Xinglong Huang, Yongjun Wang, Shushan Zhao, Yuzhen Zhu, Lijun Shen, Xin Huang, Yu Song, Ming Wang, Kai Cui, Qidong Yang
Publikováno v:
Frontiers in Earth Science, Vol 11 (2023)
Bystudying the source reservoir geochemical characteristics, reservoir cap physical properties, gas-bearing characteristics and reservoir-forming types of the coal-measure gas (CMG) accumulation system, the potential of CMG resources in the Huanghebe
Externí odkaz:
https://doaj.org/article/29f2275445524e89b3e2f35e74a89bba
Autor:
Shuyan Sheng, Xinyi Wang, Xin Liu, Xinyang Hu, Yubao Shao, Gaoyuan Wang, Deshen Mao, Conghan Li, Bangjie Chen, Xiaoyu Chen
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by symmetrical polyarthritis as its main clinical manifestation. Uncontrolled RA eventually leads to joint deformities and loss of function. Currently, the pathogenesis of RA re
Externí odkaz:
https://doaj.org/article/2216c9b828dc4d81861b2ede4506140e
Autor:
Lanxin Bao, Jing Ye, Nannan Liu, Yubao Shao, Wenhao Li, Xuefei Fan, Dahai Zhao, Hongzhi Wang, Xiaoyu Chen
Publikováno v:
Molecules, Vol 27, Iss 23, p 8475 (2022)
Interstitial lung disease associated with rheumatoid arthritis (RA-ILD) can lead to interstitial fibrosis and even lung failure as a complication of rheumatoid arthritis (RA), and there is currently no effective treatment and related basic research.
Externí odkaz:
https://doaj.org/article/14ff934479754143aefb59a6401a628b
Publikováno v:
Journal of Inflammation Research.
Gaoyuan Wang,1 Xiaoyu Chen,2 Yubao Shao,2 Bin Xu1 1Department of Orthopaedics, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, Peopleâs Republic of China; 2Department of Histology and Embryology, Anhui Medical University
Autor:
Haixia Liu, Xinyu Ding, Linyi Liu, Qianglong Mi, Quanju Zhao, YuBao Shao, Chaowei Ren, Jinju Chen, Ying Kong, Xing Qiu, Nicola Elvassore, Xiaobao Yang, Qianqian Yin, Biao Jiang
Publikováno v:
European Journal of Medicinal Chemistry. 252:115295
Autor:
Xiaobao Yang, Ren Chaowei, Bei Yang, Yubao Shao, Chen Jinju, Xinyu Ding, Kong Ying, Linyi Liu, Youwei Xu, Yin Qianqian, Biao Jiang, Ning Sun, Renhong Sun, Xianfang Zhang, Quanju Zhao
Publikováno v:
Journal of Medicinal Chemistry. 62:9281-9298
The oncogenic fusion protein BCR-ABL is the driving force of leukemogenesis in chronic myeloid leukemia (CML). Despite great progress for CML treatment through application of tyrosine kinase inhibitors (TKIs) against BCR-ABL, long-term drug administr
Autor:
Haixia Liu, Xing Qiu, Linyi Liu, Biao Jiang, Xiaobao Yang, Xinyu Ding, Ren Chaowei, Kong Ying, Yubao Shao, Nicola Elvassore, Quanju Zhao, Qianglong Mi, Chen Jinju, Yin Qianqian
Publikováno v:
European journal of medicinal chemistry. 223
Protein degradation is a promising strategy for drug development. Proteolysis-targeting chimeras (PROTACs) hijacking the E3 ligase cereblon (CRBN) exhibit enormous potential and universal degradation performance due to the small molecular weight of C