Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yuanzhuo, Gao"'
Autor:
Hua Xie, Youhong Hu, Yingqiang Liu, Zhicheng Xie, W.J. Ren, Wei Tang, Wei Aihuan, Limin Zeng, Bing Wu, Caigui Xiang, Linjiang Tong, Yuanzhuo Gao
Publikováno v:
Journal of Medicinal Chemistry. 63:1397-1414
Colony-stimulating factor 1 receptor (CSF-1R) is involved in inflammatory disorders as well as in many types of cancer. Based on high-throughput screening and docking results, we performed a detailed structure-activity-relationship study, leading to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a77132ebc7d60e4a21cc1b9ad77a7c04
https://doi.org/10.1021/acs.jmedchem.9b01912
https://doi.org/10.1021/acs.jmedchem.9b01912
Autor:
Yanwei Wu, Qian Li, Huimin Lu, Bing Wu, Yuanzhuo Gao, Xiaoqian Yang, Qing Qi, Hongwen Zhu, Chunlan Feng, Jianping Zuo, Heng Li, Chen Fan, Zongwang Zhang, Wei Tang, Hu Zhou
Publikováno v:
Pharmacological research. 169
Triptolide has shown a good immunosuppressive effect on autoimmune diseases. However, the toxicity limited its widely clinical practice. In this study, we investigated the effects and underlying mechanisms of (5R)-5-hydroxytriptolide (LLDT-8), a nove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c72bb600f8828f5135d6f40b4d097040
https://pubmed.ncbi.nlm.nih.gov/34015449
https://pubmed.ncbi.nlm.nih.gov/34015449
Autor:
Heng Li, Bing Wu, Chunlan Feng, Huimin Lu, Jianping Zuo, Qing Qi, Chen Fan, Yuanzhuo Gao, Wei Tang, Zongwang Zhang, Yanwei Wu
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 34(6)
Hemoglobin-derived heme was reported to play protective roles in hemorrhagic diseases by modulating the macrophages toward recovery. Mucosal bleeding is one of the pathological features of inflammatory bowel diseases (IBD). However, whether heme prov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d74af43fd67efa53ffa95eaa92ab304
https://pubmed.ncbi.nlm.nih.gov/32301543
https://pubmed.ncbi.nlm.nih.gov/32301543
Autor:
Zhicheng, Xie, Bing, Wu, Yingqiang, Liu, Wenming, Ren, Linjiang, Tong, Caigui, Xiang, Aihuan, Wei, Yuanzhuo, Gao, Limin, Zeng, Hua, Xie, Wei, Tang, Youhong, Hu
Publikováno v:
Journal of medicinal chemistry. 63(3)
Colony-stimulating factor 1 receptor (CSF-1R) is involved in inflammatory disorders as well as in many types of cancer. Based on high-throughput screening and docking results, we performed a detailed structure-activity-relationship study, leading to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b0c9850d9a29e2086e3787f1af93ab7d
https://pubmed.ncbi.nlm.nih.gov/31934767
https://pubmed.ncbi.nlm.nih.gov/31934767
Autor:
Yanwei Wu, Chen Fan, Qing Qi, Chunlan Feng, Huimin Lu, Heng Li, Wei Tang, Yu-xi Yan, Jianping Zuo, Bing Wu, Yuanzhuo Gao
Publikováno v:
SSRN Electronic Journal.
Background The receptor-interacting protein kinase 1 (RIPK1) has emerged as a key upstream regulator that controls the inflammatory response via its kinase-dependent and independent functions, which makes it an attractive target for developing new dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcaa57f63519392a0ee8a892efab384a
https://doi.org/10.2139/ssrn.3452093
https://doi.org/10.2139/ssrn.3452093
Autor:
Qing Qi, Heng Li, Jianping Zuo, Huimin Lu, Wei Tang, Yuanzhuo Gao, Chunlan Feng, Xiaoqian Yang, Yanwei Wu, Chen Fan, Fenghua Zhu, Pei-Lan He
Publikováno v:
Br J Pharmacol
Background and purpose Ulcerative colitis (UC) is an aetiologically refractory inflammatory disease, accompanied by dysfunction of the epithelial barrier and intestinal inflammation. Phosphodiesterase-4 (PDE4) serves as an intracellular proinflammato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::232a0090807c14b1fb20a01b3c1ecb73
https://pubmed.ncbi.nlm.nih.gov/30883697
https://pubmed.ncbi.nlm.nih.gov/30883697