Zobrazeno 1 - 10
of 308
pro vyhledávání: '"Yuanzhen Zhang"'
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 283, Iss , Pp 116929- (2024)
During pregnancy, the maternal body undergoes a series of adaptative physiological changes, leading to a slight increase in serum bile acid (BA) levels. Although the fetal liver can synthesize BAs since the first trimester through the alternative pat
Externí odkaz:
https://doaj.org/article/d268a612003e494c9026718331f93716
Autor:
Yu Bai, Tao Wu, Jun Lin, Shuwen Xu, Xian Zeng, Xuyao Zhang, Jiajun Fan, Dianwen Ju, Mengyang Li, Yanyang Nan, Xiaozhi Hu, Kaicheng Zhou, An Zhu, Zihan Dou, Zhonglian Cao, Xumeng Zhang, Yuanzhen Zhang, Xuebin Wang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 9 (2024)
Background The main challenge against patients with cancer to derive benefits from immune checkpoint inhibitors targeting PD-1/PD-L1 appears to be the immunosuppressive tumor microenvironment (TME), in which IL-33/ST2 signal fulfills critical functio
Externí odkaz:
https://doaj.org/article/638af0fc590f47d4ba79bf0e0c80b015
Autor:
Xiaozhi Hu, Yanyang Nan, Yuting Zhang, Jiajun Fan, Hanqi Wang, Yu Bai, Yuanzhen Zhang, Xuyao Zhang, Zeguo Zhu, Zhonglian Cao, Xiaomiao Ye, Tao Wu, Shuwen Xu, Zhengyu Wu, Wei Hu, Dianwen Ju
Publikováno v:
Pharmacological Research, Vol 210, Iss , Pp 107486- (2024)
Atherosclerosis (AS) ultimately cause major adverse cardiovascular events (MACEs). While traditional strategies by lipid-reducing have reduced MACEs, many patients continue to face significant risks. It might attribute to the upregulation of CD47 exp
Externí odkaz:
https://doaj.org/article/637d954985274bcfaf351c2a9e188bf5
Autor:
Yu Bai, Yanyang Nan, Tao Wu, An Zhu, Xinlei Xie, Yun Sun, Yong Deng, Zihan Dou, Xiaozhi Hu, Rongrui Zhou, Shuwen Xu, Yuanzhen Zhang, Jiajun Fan, Dianwen Ju
Publikováno v:
Advanced Science, Vol 11, Iss 31, Pp n/a-n/a (2024)
Abstract Non‐alcoholic fatty liver disease (NAFLD) is a prominent cause of various chronic metabolic hepatic diseases with limited therapeutics. Rubicon, an essential regulator in lysosomal degradation, is reported to exacerbate hepatic steatosis i
Externí odkaz:
https://doaj.org/article/7076b9e7f384429c8ad5b42cfcce2c86
Autor:
Yuqi Shao, Saisai Yang, Lin Cheng, Jie Duan, Jin Li, Jiawei Kang, Fang Wang, Juan Liu, Fang Zheng, Jianhong Ma, Yuanzhen Zhang
Publikováno v:
Molecular Cytogenetics, Vol 17, Iss 1, Pp 1-10 (2024)
Abstract Objective The primary object of this study is to analyze chromosomal abnormalities in miscarriages detected by copy number variants sequencing (CNV-Seq), establish potential pathways or genes related to miscarriages, and provide guidance for
Externí odkaz:
https://doaj.org/article/72384a310523490db2d181319683c33a
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Congenital heart defect (CHD) is the most common congenital abnormality, and it has long been a clinical and public health concern. Our previous findings have found Periostin (POSTN) and Pappalysin-1 (PAPPA) as potential biomarker
Externí odkaz:
https://doaj.org/article/2f71e35505304956a8d3a5dc0336082e
Autor:
Yuqi Shao, Saisai Yang, Jiafu Li, Lin Cheng, Jiawei Kang, Juan Liu, Jianhong Ma, Jie Duan, Yuanzhen Zhang
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Objective: The article aims to provide genetic counseling to a family with two children who were experiencing growth and developmental delays.Methods: Clinical information of the proband was collected. Peripheral blood was collected from core family
Externí odkaz:
https://doaj.org/article/eeb6893c99df476f9ebfdf205f056caa
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 172, Iss , Pp 116246- (2024)
Azithromycin, a commonly used macrolide antibiotic for treating chlamydial infections during pregnancy, has sparked investigations into its potential effects on offspring development. Despite these inquiries, there remains uncertainty about the speci
Externí odkaz:
https://doaj.org/article/d8ae8b670c804ee593a89154a89f6972
Autor:
Huanhuan Yang, Jun Huang, Hao Zheng, Yunfan Zhang, Yuanzhen Zhang, Wei Liu, Jinrong Wu, Xiaobin Chen, Jinfeng Lin, Yanna Ni, Xiaojing Nie
Publikováno v:
BMC Medical Genomics, Vol 16, Iss 1, Pp 1-6 (2023)
Abstract Background 1P36 deletion syndrome is recognized as the most common terminal microdeletion syndrome in humans, characterized by early developmental delay and consequent intellectual disability, seizure disorder, and distinctive facial feature
Externí odkaz:
https://doaj.org/article/a1428a035fcb4ac7bffc25753ea03e30
Publikováno v:
Reproductive Biology and Endocrinology, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Background Diminished ovarian reserve (DOR) is a common cause of female infertility, with genetic factors being a significant contributor. However, due to high genetic heterogeneity, the etiology of DOR in many cases remains unknown. In this
Externí odkaz:
https://doaj.org/article/51768fca391f461594795bd040b9eb85