Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Yuanzhe Guan"'
Autor:
Christof Fellmann, Thomas Hoffmann, Vaishali Sridhar, Barbara Hopfgartner, Matthias Muhar, Mareike Roth, Dan Yu Lai, Inês A.M. Barbosa, Jung Shick Kwon, Yuanzhe Guan, Nishi Sinha, Johannes Zuber
Publikováno v:
Cell Reports, Vol 5, Iss 6, Pp 1704-1713 (2013)
Short hairpin RNA (shRNA) technology enables stable and regulated gene repression. For establishing experimentally versatile RNAi tools and minimizing toxicities, synthetic shRNAs can be embedded into endogenous microRNA contexts. However, due to our
Externí odkaz:
https://doaj.org/article/989d8540a74d47cb99c674fb1963f415
Autor:
Alexandra M. Amen, Ryan M. Loughran, Chun-Hao Huang, Rachel J. Lew, Archna Ravi, Yuanzhe Guan, Emma M. Schatoff, Lukas E. Dow, Brooke M. Emerling, Christof Fellmann
Publikováno v:
Cell reports methods, vol 2, iss 7
We present Multi-miR, a microRNA-embedded shRNA system modeled after endogenous microRNA clusters that enables simultaneous expression of up to three or four short hairpin RNAs (shRNAs) from a single promoter without loss of activity, enabling robust
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6908663862a8a6e6457494cbe28cb5ea
https://pubmed.ncbi.nlm.nih.gov/35880017
https://pubmed.ncbi.nlm.nih.gov/35880017
Autor:
Raphael Pelossof, Christof Fellmann, Qing Xiang, Darjus F. Tschaharganeh, Thomas Hoffmann, Vishal Thapar, Christina S. Leslie, Johannes Zuber, Ralph Garippa, Scott W. Lowe, Yuanzhe Guan, Chun-Hao Huang, Gunnar Rätsch, Nishi Sinha, Prem K. Premsrirut, Christian Widmer, Lauren Fairchild, Dan-Yu Lai, Vipin T. Sreedharan
Publikováno v:
Nature biotechnology
We present SplashRNA, a sequential classifier to predict potent microRNA-based short hairpin RNAs (shRNAs). Trained on published and novel data sets, SplashRNA outperforms previous algorithms and reliably predicts the most efficient shRNAs for a give
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::882a7982313d98863f3c1a8eae92ab82
https://doi.org/10.1038/nbt.3807
https://doi.org/10.1038/nbt.3807
Autor:
Jung Shick Kwon, Vaishali Sridhar, Mareike Roth, Nishi Sinha, Johannes Zuber, Christof Fellmann, Dan Yu Lai, Yuanzhe Guan, Inês Am Barbosa, Matthias Muhar, Barbara Hopfgartner, Thomas Hoffmann
Publikováno v:
Cell Reports, Vol 5, Iss 6, Pp 1704-1713 (2013)
SummaryShort hairpin RNA (shRNA) technology enables stable and regulated gene repression. For establishing experimentally versatile RNAi tools and minimizing toxicities, synthetic shRNAs can be embedded into endogenous microRNA contexts. However, due
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0369123a2bcaf2d1f7d66a1c590281
http://www.sciencedirect.com/science/article/pii/S2211124713006876
http://www.sciencedirect.com/science/article/pii/S2211124713006876